An Xian (Sichuan) zhi : 30 juan, juan shou : 1 juan /

Double leaves, oriental style, in case.

Huang'an xian (Hubei) zhi : 10 juan, juan shou : 1 juan /

Double leaves, oriental style, in case.

Tong'an xian (Fujian) zhi : 30 juan, juan shou : 1 juan /

Double leaves, oriental style, in case.

Yong'an xian (Guangdong) san zhi : 5 juan, juan shou : 1 juan, juan mo : 1 juan, tu : 45 fu /

Qing Daoguang yuan nian [1821] xiu.

Tai'an xian zhi : [12 juan, juan shou 1 juan, juan mo 1 juan] /

On double leaves, oriental style, in 2 cases.

An address delivered at Deerfield before the Society of Adelphi on the evening of Jan. 1, 1837.

Mode of access: Internet.

Twelve precisely! or, A night at Dover: an interlude, in one act. As performed at the Olympic Theatre, Strand, Monday, Jan 1, 1821.

Mode of access: Internet.

Surplus property sale, Lockland, Ohio : hearings before a subcommittee ... Eightieth Congress, first session, on S. Res. 75, a resolution authorizing an investigation of surplus property and its disposal. April 1, 24, 29, May 6 and 7, 1947.

Mode of access: Internet.

An alternative to annualizing the cost-of-living adjustments on federal retirement : hearing before the Subcommittee on Civil Service, Post Office, and General Services of the Committee on Governmental Affairs, United States Senate, Ninety-seventh Congress, first session, on S. 677 ... April 1, 1981.

Mode of access: Internet.

Revenue act of 1943 : Hearings before the Committee on Finance, United States Senate, Seventy-eighth Congress, first session, on H.R. 3687, an act to provide revenue, and for other purposes. November 29, 30, December 1, 2, 3, 4, 6, and 15, 1943.

Mode of access: Internet.

Trade agreements extension : hearings before the Committee on Finance, United States Senate, Eighty-fourth Congress, first session, on H.R. 1, an act to extend the authority of the President to enter into trade agreements under section 350 of the Tariff Act of 1930, as amended, and for other purposes.

"Index by general categories, pts. 1-4" issued seperately.

Cataloging as an asset; an address to the New York State Library School, May 1, 1915.

On cover: From G. K. Hall & Co. with all good wishes at Christmas MCMLXVIII.

Cardiotrophin-like cytokine/cytokine-like factor 1 is an essential trophic factor for lumbar and facial motoneurons in vivo

The ciliary neurotrophic factor alpha-receptor(CNTFRalpha) is required for motoneuron survival during development, but the relevant ligand(s) has not been determined. One candidate is the heterodimer formed by cardiotrophin-like cytokine (CLC) and cytokine-like factor 1 (CLF). CLC/CLF binds to CNTFRalpha and enhances the survival of developing motoneurons in vitro; whether this novel trophic factor plays a role in neural development in vivo has not been tested. We examined motor and sensory neurons in embryonic chicks treated with CLC and in mice with a targeted deletion of the clf gene. Treatment with CLC increased the number of lumbar spinal cord motoneurons that survived the cell death period in chicks. However, this effect was regionally specific, because brachial and thoracic motoneurons were unaffected. Similarly, newborn clf -/- mice exhibited a significant reduction in lumbar motoneurons, with no change in the brachial or thoracic cord. Clf deletion also affected brainstem motor nuclei in a regionally specific manner; the number of motoneurons in the facial but not hypoglossal nucleus was significantly reduced. Sensory neurons of the dorsal root ganglia were not affected by either CLC treatment or clf gene deletion. Finally, mRNA for both clc and clf was found in skeletal muscle fibers of embryonic mice during the motoneuron cell death period. These findings support the view that CLC/CLF is a target-derived factor required for the survival of specific pools of motoneurons. The in vivo actions of CLC and CLF can account for many of the effects of CNTFRalpha on developing motoneurons.

Enzymatic cyclization of a potent Bowman-Birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide

The most potent known naturally occurring Bowman-Birk inhibitor, sunflower trypsin inhibitor-1 (SFTI-1), is a bicyclic 14-amino acid peptide from sunflower seeds comprising one disulfide bond and a cyclic backbone. At present, little is known about the cyclization mechanism of SFTI-1. We show here that an acyclic permutant of SFTI-1 open at its scissile bond, SFTI-1[ 6,5], also functions as an inhibitor of trypsin and that it can be enzymatically backbone-cyclized by incubation with bovine beta-trypsin. The resulting ratio of cyclic SFTI-1 to SFTI1[6,5] is similar to9:1 regardless of whether trypsin is incubated with SFTI-1[ 6,5] or SFTI-1. Enzymatic resynthesis of the scissile bond to form cyclic SFTI-1 is a novel mechanism of cyclization of SFTI-1[ 6,5]. Such a reaction could potentially occur on a trypsin affinity column as used in the original isolation procedure of SFTI-1. We therefore extracted SFTI-1 from sunflower seeds without a trypsin purification step and confirmed that the backbone of SFTI-1 is indeed naturally cyclic. Structural studies on SFTI-1[ 6,5] revealed high heterogeneity, and multiple species of SFTI-1[ 6,5] were identified. The main species closely resembles the structure of cyclic SFTI-1 with the broken binding loop able to rotate between a cis/trans geometry of the I7-P8 bond with the cis conformer being similar to the canonical binding loop conformation. The non-reactive loop adopts a beta-hairpin structure as in cyclic wild-type SFTI-1. Another species exhibits an isoaspartate residue at position 14 and provides implications for possible in vivo cyclization mechanisms.