The biochemistry of drug metabolism--an introduction: part 5. Metabolism and bioactivity.

This review continues a general presentation of the metabolism of drugs and other xenobiotics begun in five recent issues of Chemistry & Biodiversity. The present Part is dedicated to the pharmacological and toxicological consequences of drug and xenobiotic metabolism. In other words, the key concepts here are activation vs. deactivation, toxification vs. detoxification, and their interplay. These concepts are illustrated with a number of medicinally, toxicologically, and environmentally relevant examples. But, far from being concerned only with individual cases, the review is based on broad classifications, global rationalizations, and synthetic hypotheses.

5-2-19 [i.e. 5-2-20], exposition [internationale] d'aviculture au Grand Palais [pigeon en cage, son diplôme de bague d'honneur et un de ses colombogrammes] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57880

Iowa Community Empowerment Newsletter, February 2004, Vol.5, no.1

Monthly newsletter for the Iowa Department of Public Health

5-2-19 [i.e. 5-2-20], exposition [internationale] d'aviculture au Grand Palais [vue d'ensemble des différentes cages] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57882

5-2-19 [i.e. 5-2-20], réception du maréchal Foch à l'Institut : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57889

5-2-19 [i.e. 5-2-20], réception du maréchal Foch à l'Institut : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57885

Le pont de l'Alma, crue de la Seine, 5/1/20 : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57528

ABD e-News, March 5, 2004

March 5, 2004 e-news newsletter

5/1/20, crue de la Seine, porte d'Ivry : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57522 bis