1000 resultados para 110199 Medical Biochemistry and Metabolomics not elsewhere classified
Resumo:
One of the challenges for software engineering is collecting meaningful data from industrial projects. Software process improvement depends on measurement to provide baseline status and confirming evidence of the effect of process changes. Without data, any conclusions rely on intuition and guessing. The Team Software ProcessSM (TSPSM) provides a powerful framework for data collection and analysis, in addition to its primary goal as a basis for highly effective software development. In this paper, we describe the experiences of, and benefits realized by, a team using the TSP for the first time. By reviewing how this particular team collected and used data, we show features of the TSP that make it a powerful foundation for software process improvement.
Resumo:
The inherent neurotoxic potential ofthe endogenous excitatory amino acid glutamate, may be causally related to the pathogenesis ofAD neurodegeneration disorders. Neuronal excitotoxicity is conceivably mediated by the N-methyl-D-aspartate-(NMDA)-Ca2+- ionotropic receptor. NMDA receptors exist as multimeric complexes comprising proteins from two families – NR1 and NR2(A-D). The polyamines, spermine and spermidine bind to, and modulate NMDA receptor efficacy via interaction with exon 5, an alternatively-spliced, 21 amino acid, N-terminal cassette. AD associated cognitive impairment may therefore occur via subunitspecific NMDA receptor dysfunction effecting regional selectivity of neuronal degradation.
Resumo:
We discuss how integrity consistency constraints between different UML models can be precisely defined at a language level. In doing so, we introduce a formal object-oriented metamodeling approach. In the approach, integrity consistency constraints between UML models are defined in terms of invariants of the UML model elements used to define the models at the language-level. Adopting a formal approach, constraints are formally defined using Object-Z. We demonstrate how integrity consistency constraints for UML models can be precisely defined at the language-level and once completed, the formal description of the consistency constraints will be a precise reference of checking consistency of UML models as well as for tool development.
Resumo:
The texture segmentation techniques are diversified by the existence of several approaches. In this paper, we propose fuzzy features for the segmentation of texture image. For this purpose, a membership function is constructed to represent the effect of the neighboring pixels on the current pixel in a window. Using these membership function values, we find a feature by weighted average method for the current pixel. This is repeated for all pixels in the window treating each time one pixel as the current pixel. Using these fuzzy based features, we derive three descriptors such as maximum, entropy, and energy for each window. To segment the texture image, the modified mountain clustering that is unsupervised and fuzzy c-means clustering have been used. The performance of the proposed features is compared with that of fractal features.
Resumo:
A framework is a reusable design that requires software components to function. To instantiate a framework, a software engineer must provide the software components required by the framework. To do this effectively, the framework-component interfaces must be specified so the software engineer knows what assumptions the framework makes about the components, and so the components can be verified against these assumptions. This paper presents an approach to specifying software frameworks. The approach involves the specification of the framework’s syntax, semantics, and the interfaces between the framework and its components. The approach is demonstrated with a simple case study.