989 resultados para testicular format


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En el present treball es definirà el cicle de vida i la metodologia que s'ha de seguir, segons el disseny centrat en l'usuari, per a un projecte web orientat a continguts específics per a persones de la tercera edat, per a això, es determinarà i justificarà quins mètodes i tècniques d'avaluació de la usabilitat són els més adequats per poder dissenyar un lloc web d'aquest tipus.

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El PEscola és un programa de gestió d'alumnes, professors i assignatures d'un centre d'adults. Permet introduir l'avaluació dels alumnes, i gestionar els pagaments i l'entrega de documentació. Envia sms a grups d'alumnes i genera documentació (certificats i llistes) en format odt o ods.

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SUMMARY: MetaNetX.org is a website for accessing, analysing and manipulating genome-scale metabolic networks (GSMs) as well as biochemical pathways. It consistently integrates data from various public resources and makes the data accessible in a standardized format using a common namespace. Currently, it provides access to hundreds of GSMs and pathways that can be interactively compared (two or more), analysed (e.g. detection of dead-end metabolites and reactions, flux balance analysis or simulation of reaction and gene knockouts), manipulated and exported. Users can also upload their own metabolic models, choose to automatically map them into the common namespace and subsequently make use of the website's functionality. Availability and implementation: MetaNetX.org is available at http://metanetx.org. CONTACT: help@metanetx.org.

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Este documento es la memoria de un proyecto de Fin de Máster en Software Libre cursado en la Universitat Oberta de Catalunya.El nombre del proyecto es "libmsvg" y se enmarca en la especialidad de desarrollo de aplicaciones de software libre."libmsvg" es una pequeña librería software, escrita en C, para leer y grabar ficheros en un subconjunto del formato SVG.SVG son las iniciales de Scalable Vector Graphics, un formato de gráficos vectoriales definido por el World Wide Web Consortium.En esta memoria se describe la concepción, diseño y desarrollo de la librería y los trabajos realizados para su publicación y puesta a disposición de la comunidad, como software libre.

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During the past twenty years, various instruments have been developed for the assessment of substance use in adolescents, mainly in the United States. However, few of them have been adapted to, and validated in, French-speaking populations. Consequently, although increasing alcohol and drug use among teenagers has become a major concern, the various health and social programs developed in response to this specific problem have received little attention with regard to follow-up and outcome assessment. A standardized multidimensional assessment instrument adapted for adolescents is needed to assess the individual needs of adolescents and assign them to the most appropriate treatment setting, to provide a single measurement within and across health and social systems, and to conduct treatment outcome evaluations. Moreover, having an available instrument makes it possible to develop longitudinal and trans-cultural research studies. For this reason, a French version of the Adolescent Drug Abuse Diagnosis (ADAD) was developed and validated at the University Child and Adolescent Psychiatric Clinic in Lausanne, Switzerland. This paper aims to discuss the methodological issues that we faced when using the ADAD instrument in a 4-year longitudinal study including adolescent substance users. Methodological aspects relating to the content and format of the instrument, the assessment administration and the statistical analyses are discussed.

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La responsabilidad del ERIE Psicosocial a la hora de realizar su labor en el marco de la intervención en emergencias debe ir necesariamente acompañada de una correcta identificación de las necesidades que el equipo tiene en lo que respecta a su formación e instrucción, de cara a mantener el nivel de respuesta en su labor. El desarrollo de herramientas y métodos capaces de definir estas variables es, pues el primer paso de este proceso. El formato de desarrollo posterior de esas acciones formativas, teniendo en cuenta el carácter grupal y cooperativo del grupo, debe ser estudiado y validado para obtener la máxima eficacia durante su materialización.

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Reaching and educating the masses to the benefit of all of mankind is the ultimate goal and through the use of this technology facility/tool many can be reached in their own language, in their own community, in their own time and at their own pace. Making this content available to those who will benefit from the information, is vital. These people who want to consume the content are not necessarily that interested in the qualification, they need the information. Making the content available in an auditory format may also help those who may not be as literate as others. The uses of audio/ recorded lessons have a number of uses and should not just be seen as a medium for content distribution to distant communities. Recording lectures makes it possible for a lecturer to present lectures to a vast number of students, while just presenting the lecture once.

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Smarthistory.org is a proven, sustainable model for open educational resources in the Humanities. We discuss lessons learned during its agile development. Smarthistory.org is a free, creative-commons licensed, multi-media web-book designed as a dynamic enhancement or substitute for the traditional art history textbook. It uses conversation instead of the impersonal voice of the typical textbook in-order to reveal disagreement, emotion, and the experience of looking. The listener remains engaged with both the content and the interaction of the speakers. These conversations model close looking and a willingness to encounter and engage the unfamiliar. Smarthistory takes the inherent dialogic and multimedia nature of the web and uses it as a pedagogical method. This extendable Humanities framework uses an open-source content management system making Smarthistory inexpensive to create, and easy to manage and update. Its chronological timeline/chapter-based format integrates new contributions into a single historical framework, a structure applicable across the Humanities.

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Background. During the last few years, PCR-based methods have been developed to simplify and reduce the time required for genotyping Mycobacterium tuberculosis (MTB) by standard approaches based on IS6110-Restriction Fragment Length Polymorphism (RFLP). Of these, MIRU-12-VNTR (Mycobacterial interspersed repetitive units- variable number of tandem repeats) (MIRU-12) has been considered a good alternative. Nevertheless, some limitations and discrepancies with RFLP, which are minimized if the technique is complemented with spoligotyping, have been found. Recently, a new version of MIRU-VNTR targeting 15 loci (MIRU-15) has been proposed to improve the MIRU-12 format. Results. We evaluated the new MIRU-15 tool in two different samples. First, we analyzed the same convenience sample that had been used to evaluate MIRU-12 in a previous study, and the new 15-loci version offered higher discriminatory power (Hunter-Gaston discriminatory index [HGDI]: 0.995 vs 0.978; 34.4% of clustered cases vs 57.5%) and better correlation (full or high correlation with RFLP for 82% of the clusters vs 47%). Second, we evaluated MIRU-15 on a population-based sample and, once again, good correlation with the RFLP clustering data was observed (for 83% of the RFLP clusters). To understand the meaning of the discrepancies still found between MIRU-15 and RFLP, we analyzed the epidemiological data for the clustered patients. In most cases, splitting of RFLP-clustered patients by MIRU-15 occurred for those without epidemiological links, and RFLP-clustered patients with epidemiological links were also clustered by MIRU-15, suggesting a good epidemiological background for clustering defined by MIRU-15. Conclusion. The data obtained by MIRU-15 suggest that the new design is very efficient at assigning clusters confirmed by epidemiological data. If we add this to the speed with which it provides results, MIRU-15 could be considered a suitable tool for real-time genotyping.

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Fins a la darreria del segle VIII, el complex episcopal gironí se situava fora murs, al voltant de l'esglésiamartirial de Sant Feliu; a principis del segle IX, el complex es desdoblà amb la consagració d'una segona església episcopal, Santa Maria, dins murs, raó per la qual la seu fou coneguda, al llarg d'aquella centúria, amb la doble advocació de Santa Maria i Sant Feliu. Al llarg del segle X, s'afermà la preeminència de Santa Maria fins al punt que, en l'últim terç del segle. Sant Feliu ja no és esmentada com a seu episcopal, encara que hi continuà vinculada com a una església dependent, sense personalitat ni administració pròpia. Des de final del segle, el procés s'accelerà amb la construcció d'una nova església catedral a Santa Maria, que complementà l'aixecament d'un nou complex episcopal dins murs, en gran part culminat a mitjan segle XI i format per xenodoquium, catedral, palau episcopal i conjunt canonical, a banda de noves residències de canonges i altres clergues en el seu entorn. Aquests fets significaren la consolidació de Santa Maria com a seu única, però també la profunda remodelació urbanística d'un sector significatiu de la ciutat, prop d'un 20% del total, expressió del nou domini del bisbe i dels clergues sobre la 'seva ciutat'

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La present comunicació pretén ressenyar l’aportació dels Atles comarcals de Catalunya al coneixement del nostre territori com una obra no només de caire acadèmic sinó també divulgatiu i aplicat. En primer lloc, es constata la filiació de l’obra al llegat de la geografia clàssica catalana i a les aportacions tradicionals —monografies i les obres generals― que han disseccionat el país des de l’òptica comarcal. En segon lloc, es detalla el seu procés de concepció i elaboració. Finalment, es destaquen les innovacions que el nou format CD-Rom i les possibilitats d’interacció cartogràfica amb servidors externs suposen en el sentit d’innovació respecte de les aportacions anteriors

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A new multiplex assay platform was evaluated to detect Trypanosoma cruzi infection using the recombinant antigens CRA, FRA, CRAFRA fusion and parasite lysate. The antigens presented different sensitivity and specificity in a singleplex test when compared to a serial dilution of two pools comprising 10 positive serum samples and one pool of 10 negative samples. The recombinant protein CRA presented lower sensitivity (55%) in contrast to the 100% specificity and sensitivity of FRA, CRAFRA and T. cruzi lysate. These antigens also showed good results in a duplex test and the duplex test with CRAFRA/T. cruzi lysate showed better performance with 100% specificity and sensitivity, as well as a lower cut-off value in comparison to the other duplex test, FRA/T. cruzi lysate. Hence, when the antigens were used in duplex format, both tests showed decreased cut-off values and no interference between different bead sets, resulting in increasing sensitivity and specificity. The results of these multiplex tests show that they could be an alternative to singleplex detection for Chagas disease, and also indicate the necessity of using multiplex diagnostic tools to increase the sensitivity and specificity for diagnostic tests. Emerging data from the T. cruzi genome and from its ORFeome project will also allow the identification of new antigens for this disease detection application.

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This paper explores the plurality of institutional environments in which standards for the service sector are expected to support the rise of a global knowledge-based economy. Despite the careful wording of the World Trade Organization (WTO), a whole range of international bodies still have the capacity to define technical specifications affecting how services are expected to be traded on worldwide basis. The analysis relies on global political economy approaches to extend to the area of service standards the assumption that the process of globalization is not opposing states and markets, but a joint expression of both of them including new patterns and agents of structural change through formal and informal power and regulatory practices. It analyses on a cross-institutional basis patterns of authority in the institutional setting of service standards in the context of the International Organisation for Standardisation (ISO), the European Union, and the United States. In contrast to conventional views opposing the American system to the ISO/European framework, the paper questions the robustness of this opposition by showing that institutional developments of service standards are likely to face trade-offs and compromises across those systems and between two opposing models of standardisation.

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Objectif : l'objectif de cette étude est de déterminer le nombre d'enfant de 0 à 6 mois de la population vaudoise ayant eu recours à l'ostéopathie, de caractériser les motivations des parents à consulter un ostéopathe pour leur enfant, d'évaluer le niveau de satisfaction d'une telle prise en charge et d'établir un profil de parents type s'il en existe un. Méthode : La méthodologie utilisée dans cette recherche prospective s'est faite au moyen d'un questionnaire accessible aux parents des sujets d'étude en format papier ou en format numérique disponible en ligne sur internet. La distribution des questionnaires s'est faite par l'intermédiaire de pédiatres installés, de sages-femmes à domicile, de mamans de jour et s'est déroulée sur une période de 3 mois à la fin de l'année 2011. Résultats : 73.3% des sujets sondés disent avoir consulté au moins une fois un ostéopathe pour leur enfant. Dans une grande majorité des cas les causes du recours à l'ostéopathie sont, d'un point de vue strictement médical, des événements fréquents et relativement banaux dans les premiers mois de vie des enfants. Beaucoup de parents consultent un ostéopathe pour effectuer un contrôle « général » de leur enfant, souvent avant même le premier rendez-vous chez leur pédiatre. Ils sont en majorité satisfaits de la manipulation et envisagent de se rendre à nouveau chez ce praticien en cas de besoin ou pour un simple contrôle du développement de leur enfant. Il ressort de cette analyse trois profils de parents : les parents n'ayant pas recours à l'ostéopathe pour leur enfant, les parents ayant recours à cette thérapie occasionnellement et les parents y ayant recours fréquemment. Ces trois profils de parents se définissent uniquement sur l'usage ou non de l'ostéopathie pour l'enfant et de sa fréquence mais ils ne sont pas influencés par les ressources financières des parents et leur propre recours à l'ostéopathie. Conclusion : Cette étude a permis de constater que le nombre de parents ayant recours à l'ostéopathie pour leur nouveau-né est important, en effet 73,3% des sujets ont été manipulé par un ostéopathe au cours de leurs six premiers mois de vie. Le contrôle précoce du nourrisson chez un ostéopathe semble rassurer les parents sur la santé de leur enfant. L'ostéopathe s'impose ainsi comme un référent supplémentaire aux soins du nourrisson, au même titre que le pédiatre.

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The main instrument used in psychological measurement is the self-report questionnaire. One of its majordrawbacks however is its susceptibility to response biases. A known strategy to control these biases hasbeen the use of so-called ipsative items. Ipsative items are items that require the respondent to makebetween-scale comparisons within each item. The selected option determines to which scale the weight ofthe answer is attributed. Consequently in questionnaires only consisting of ipsative items everyrespondent is allotted an equal amount, i.e. the total score, that each can distribute differently over thescales. Therefore this type of response format yields data that can be considered compositional from itsinception.Methodological oriented psychologists have heavily criticized this type of item format, since the resultingdata is also marked by the associated unfavourable statistical properties. Nevertheless, clinicians havekept using these questionnaires to their satisfaction. This investigation therefore aims to evaluate bothpositions and addresses the similarities and differences between the two data collection methods. Theultimate objective is to formulate a guideline when to use which type of item format.The comparison is based on data obtained with both an ipsative and normative version of threepsychological questionnaires, which were administered to 502 first-year students in psychology accordingto a balanced within-subjects design. Previous research only compared the direct ipsative scale scoreswith the derived ipsative scale scores. The use of compositional data analysis techniques also enables oneto compare derived normative score ratios with direct normative score ratios. The addition of the secondcomparison not only offers the advantage of a better-balanced research strategy. In principle it also allowsfor parametric testing in the evaluation