Hung Out to Dry: Choice of Priority Ecoregions for Conserving Threatened Neotropical Anurans Depends on Life-History Traits

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Casearin X exhibits cytotoxic effects in leukemia cells triggered by apoptosis

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Projeções e expectativas de ingressantes no curso de formação docente em educação profissional técnica na saúde

O presente estudo propõe analisar as projeções e expectativas dos ingressantes em um curso de formação docente, que visa superar a fragmentação disciplinar e criar maior aproximação com o mundo do trabalho. Trata-se de estudo qualitativo realizado a partir de entrevistas com 33 ingressantes do curso. Para a análise dos dados, pautou-se na técnica de análise de conteúdo, modalidade temática. Os resultados do estudo permitiram elencar as seguintes categorias temáticas: possibilidade de ensinar-aprender; necessidade de capacitação pedagógica e de constante busca de aprendizagem; possibilidade de mudança da realidade. Conclui-se que os ingressantes vislumbram a transformação da realidade social na qual estão inseridos, considerando a necessidade de aquisição de novas habilidades e competências profissionais, com intuito de exercer eficazmente o trabalho e ocupar um espaço competitivo no mercado.

Lanosidade em cultivares de pêssego (Prunus persica (L.) Batsch): estudos anatômicos e ultra-estruturais

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Moonlets wandering on a leash-ring

Since the Voyager flybys, embedded moonlets have been proposed to explain some of the surprising structures observed in Saturn's narrow F ring. Experiments conducted with the Cassini spacecraft support this suggestion. Images of the F ring show bright compact spots, and seven occultations of stars by the F ring, monitored by ultraviolet and infrared experiments, revealed nine events of high optical depth. These results point to a large number of such objects, but it is not clear whether they are solid moonlets or rather loose particle aggregates. Subsequent images suggested an irregular motion of these objects so that a determination of their orbits consistent with the F ring failed. Some of these features seem to cross the whole ring. Here we show that these observations are explained by chaos in the F ring driven mainly by the 'shepherd' moons Prometheus and Pandora. It is characterized by a rather short Lyapunov time of about a few hundred orbital periods. Despite this chaotic diffusion, more than 93 per cent of the F-ring bodies remain confined within the F ring because of the shepherding, but also because of a weak radial mobility contrasted by an effective longitudinal diffusion. This chaotic stirring of all bodies involved prevents the formation of 'propellers' typical of moonlets, but their frequent ring crossings explain the multiple radial 'streaks' seen in the F ring. The related 'thermal' motion causes more frequent collisions between all bodies which steadily replenish F-ring dust and allow for ongoing fragmentation and re-accretion processes (ring recycling).

Persistência e liberação de macronutrientes e silício da fitomassa de crotalária em função da fragmentação

The persistence of straw, as well as the dynamics of nutrients release of it, are important aspects to consider in the choice of plants for composition of crop rotations in a no tillage system. Thus, the objective of this work was to evaluate the decomposition rate and macronutrients and silicon (Si) release from sunn hemp (Crotalaria juncea L.) phytomass, as a function of management, with and without fragmentation. A randomized blocks design, with four replications, in a factorial 2x6, constituted by two aboveground phytomass management after 75 days after emergence (with and without mechanical fragmentation) and six sampling times (0, 18, 32, 46, 74 and 91 days after management (DAM)), were evaluated the decomposition rate and nutrient release from sunn hemp biomass. The mechanical fragmentation of sunn hemp straw did not change the decomposition and macronutrients release. The maximum release rates occurred 0-18 DAM. Potassium is the most rapidly available nutrient, while the silicon is more slowly released to the ground. Over time there has been increasing Si content in the straw.

Exciton formation in dye doped OLEDs using electrically detected magnetic resonance

Electrically Detected Magnetic Resonance (EDMR) was used to investigate the influence of dye doping molecules on spin-dependent exciton formation in Aluminum (III) 8-hydroxyquinoline (Alq(3)) based OLEDs with different device structures and temperature ranges. 4-(dicyanomethylene)-2-methyl-6-{2-[(4-diphenylamino-phenyl]ethyl}-4H-pyran (DCM-TPA) and 5,6,11,12-tetraphenylnaphthacene (Rubrene) were used as dopants. A strong temperature dependence have been observed for doped OLEDs, with a decrease of two orders of magnitude in EDMR signal for temperatures above similar to 200 K. The signal temperature dependence were fitted supposing different spin-lattice relaxation processes. The results suggest that thermally activated vibrations of dopants molecules induce spin pair dissociation, reducing the signal.

Strong interaction effects in scalar top production

We discuss effects of fragmentation and hard gluon radiation on the signal for the pair production of the lighter scalar top eigenstate t̃1 at e+e- colliders. The main emphasis is on scenarios with small stop-LSP mass splitting, where strong interaction effects can considerably modify kinematical properties of the final state.

Diálogos intertextuais no feminino: Margaret Drabble

In The Middle Ground (1980), Margaret Drabble uses an intertextual web to depict the feminine search for identity and psychological integrity in middle age. This paper attempts to identify and analyze the absorption and integration of other texts in The Middle Ground. The dialogue, both in theme and style, with Virginia Woolf's Mrs Dalloway is initially considered, mostly from the perspective of parody. Other confluences are also studied: with Russian fairy tales, with paintings by Hans Holbein, J. B.Vanmour, Van Dyck, Claude Lorrain and Peter de Hooch, and also its references to the whole of Drabble's literary work.

Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery

In order to assess a new strategy of DNA vaccine for a more complete understanding of its action in immune response, it is important to determine the in vivo biodistribution fate and antigen expression. In previous studies, our group focused on the prophylactic and therapeutic use of a plasmid DNA encoding the Mycobacterium leprae 65-kDa heat shock protein (Hsp65) and achieved an efficient immune response induction as well as protection against virulent M. tuberculosis challenge. In the present study, we examined in vivo tissue distribution of naked DNA-Hsp65 vaccine, the Hsp65 message, genome integration and methylation status of plasmid DNA. The DNA-Hsp65 was detectable in several tissue types, indicating that DNA-Hsp65 disseminates widely throughout the body. The biodistribution was dose-dependent. In contrast, RT-PCR detected the Hsp65 message for at least 15 days in muscle or liver tissue from immunized mice. We also analyzed the methylation status and integration of the injected plasmid DNA into the host cellular genome. The bacterial methylation pattern persisted for at least 6 months, indicating that the plasmid DNA-Hsp65 does not replicate in mammalian tissue, and Southern blot analysis showed that plasmid DNA was not integrated. These results have important implications for the use of DNA-Hsp65 vaccine in a clinical setting and open new perspectives for DNA vaccines and new considerations about the inoculation site and delivery system. © 2006 Coelho-Castelo et al; licensee BioMed Central Ltd.

A família do paciente em situação crônica de vida: a visão de enfermeiros de um hospital de ensino

This exploratory descriptive study, of qualitative nature had the purpose to study how the nurses from a hospital school see the family as care participants. Six nurses from clinics of chronically ill patients were interviewed. The data analysis allowed to infer that the nurses had only little knowledge of the family's thematic during graduation, making the relationship with the accompanying families very difficult. Daily care during hospitalization period is marked by easy moments when members are willing to participate in the process, and by difficulties when they attempt to break institutional rules. It was suggested that new nurses have theoretical foundation to attend the family in several scenarios of care. It was considered the need of investments in professional training, and that the advance of humanization of services implies in exchange and integration of knowledge among patients, family members, health professionals, support staff and managers beyond the science field.

An investigation into the loss of the Brazilian space programme's launch vehicle VLS-1 V03

There has been a rapid increase in the complexity and integration of many safety-critical systems. In consequence, it is becoming increasingly difficult to identify the causes of incidents and accidents back through the complex interactions that lead to an adverse event. At the same time, there is a growing appreciation of the need to consider a broad range of contextual factors in the aftermath of any mishap. A number of regulators, operators and research teams have responded to these developments by proposing novel techniques to support the analysis of complex, safety-critical incidents. It is important to illustrate these different approaches by applying them to a number of common case studies. The following pages, therefore, show how STAMP and AcciMap might support the Serviço Público Federal investigation into the explosion and fire of the Brazilian launch vehicle VLS-1 VO3. © 2006 Elsevier Ltd. All rights reserved.

What's the signification of nuclear vacuoles in human sperm?

The aim of this study was to determine the extent of DNA fragmentation and the presence of single/denatured or double stranded of DNA in sperm with large nuclear vacuoles (LNV) selected by high-magnification. A total of 30 patients had fresh semen samples prepared by discontinuous concentration gradient. Sperm with normal nucleus (NN) and LNV were selected at 8400x magnification and placed in different slides. DNA fragmentation was determined by TUNEL assay. Denatured and double stranded DNA was identified by acridine orange fluorescence method. The percentage of DNA fragmentation in LNV sperm (29%) was significantly higher (P<0.001) than NN sperm (15.8%). Therefore, cleavage of genomic DNA in low molecular weight DNA fragments (mono and oligonucleosomes), and single strand breaks (nicks) in high molecular weight DNA occur more frequently in LNV. Identically, the percentage denatured stranded DNA in sperm with LNV (67.9%) was significantly higher (P <0.0001) than NN sperm (33%). The high level of denatured DNA in sperm with LNV suggests precocious decondensation and disaggregation of sperm chromatin fibers. Our results support an association between LNV sperm and DNA damage, and the routine selection and injection of morphological motile sperm at high magnification for ICSI. The adverse effect (DNA fragmentation or denaturation) leads to concern particularly about the possibility of iatrogenic transmission of genetic abnormalities. Copyright - SBRA - Sociedade Brasileira de Reprodução Assistida.

Geometric modeling from the medical images in the CAD system to support prosthesis design

This paper presents an individual designing prosthesis for surgical use and proposes a methodology for such design through mathematical extrapolation of data from digital images obtained via tomography of individual patient's bones. Individually tailored prosthesis designed to fit particular patient requirements as accurately as possible should result in more successful reconstruction, enable better planning before surgery and consequently fewer complications during surgery. Fast and accurate design and manufacture of personalized prosthesis for surgical use in bone replacement or reconstruction is potentially feasible through the application and integration of several different existing technologies, which are each at different stages of maturity. Initial case study experiments have been undertaken to validate the research concepts by making dimensional comparisons between a bone and a virtual model produced using the proposed methodology and a future research directions are discussed.

Integración regional e integración con Estados Unidos. El rumbo de las exportaciones centroamericanas y de República Dominicana

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