Influence of energy and polymer-escapsulated methionine supplements on mohair growth and fibre diameter of Angora goats fed at maintenance

We studied the fleece production of Angora wether goats provided with energy, to maintain liveweight, and polymer-encapsulated methionine while they were fed on poor quality roughage rations in early summer. Forty goats (mean fleece-free liveweight 28.5 kg) were randomly allotted to 5 treatments and housed individually for 12 weeks. The treatments were: control, fed to lose 5 kg liveweight; M, fed to maintain liveweight; and 3 maintenance rations with either 0.5, 1 or 2 g day-1 of polymer-encapsulated methionine. The basal ration was oaten chaff (56.8% digestible dry matter) and all maintenance- fed goats received a supplement of 150 g day- 1 gristed barley. Goats required an estimated 267 kJ ME kg-0.75 day-1 to maintain liveweight. Goats fed the control diet grew less mohair (P<0.05) with reduced mean fibre diameter (P< 0.05) than maintenance-fed goats (4.9 g day-1, 30.0 pm compared with 5.8 g day-1, 31.9 pm). For maintenance-fed animals, the addition of 1 g day- methionine (0.15% of dry matter intake) increased mohair growth by 0.8g day-1 (P<0.075). Feeding barley to prevent liveweight loss and feeding polymer-encapsulated methionine at maintenance is unlikely to result in economic responses in mohair production of goats grazing low quality summer pastures

Retinal nerve fibre layer thinning associated with diabetic peripheral neuropathy

Aims
To investigate the relationship between retinal nerve fibre layer thickness and peripheral neuropathy in patients with Type 2 diabetes, particularly in those who are at higher risk of foot ulceration.

Methods
Global and sectoral retinal nerve fibre layer thicknesses were measured at 3.45 mm diameter around the optic nerve head using optical coherence tomography (OCT). The level of neuropathy was assessed in 106 participants (82 with Type 2 diabetes and 24 healthy controls) using the 0–10 neuropathy disability score. Participants were stratified into four neuropathy groups: none (0–2), mild (3–5), moderate (6–8), and severe (9–10). A neuropathy disability score ‡ 6 was used to define those at higher risk of foot ulceration. Multivariable regression analysis was performed to assess the effect of neuropathy disability scores, age, disease duration and retinopathy on RNFL thickness.

Results
Inferior (but not global or other sectoral) retinal nerve fibre layer thinning was associated with higher neuropathy disability scores (P = 0.03). The retinal nerve fibre layer was significantly thinner for the group with neuropathy disability scores ‡ 6 in the inferior quadrant (P < 0.005). Age, duration of disease and retinopathy levels did not significantly influence retinal nerve fibre layer thickness. Control participants did not show any significant differences in thickness measurements from the group with diabetes and no neuropathy (P > 0.24 for global and all sectors).

Conclusions
Inferior quadrant retinal nerve fibre layer thinning is associated with peripheral neuropathy in patients with Type 2 diabetes, and is more pronounced in those at higher risk of foot ulceration.

What happens during natural protein fibre dissolution in ionic liquids

Here, we monitor the dissolution of several natural protein fibres such as wool, human hair and silk, in various ionic liquids (ILs). The dissolution of protein-based materials using ILs is an emerging area exploring the production of new materials from waste products. Wool is a keratin fibre, which is extensively used in the textiles industry and as a result has considerable amounts of waste produced each year. Wool, along with human hair, has a unique morphology whereby the outer layer, the cuticle, is heavily cross linked with disulphide bonds, whereas silk does not have this outer layer. Here we show how ILs dissolve natural protein fibres and how the mechanism of dissolution is directly related to the structure and morphology of the wool fibre. © 2014 by the authors; licensee MDPI, Basel, Switzerland.