Graft incorporation and implant osseointegration following the use of autologous and fresh-frozen allogeneic block bone grafts for lateral ridge augmentation

Objectives: To compare autogenous bone (AT) and fresh-frozen allogeneic bone (AL) in terms of histomorphometrical graft incorporation and implant osseointegration after grafting for lateral ridge augmentation in humans. Materials and methods: Thirty-four patients were treated with either AL (20 patients) or AT (14 patients) onlay grafts. During implant installation surgery 6 months after grafting, cylindrical biopsies were harvested perpendicularly to the lateral aspect of the augmented alveolar ridge. Additionally, titanium mini-implants were installed in the grafted regions, also perpendicularly to the ridge; these were biopsied during second-stage surgery. Histological/histomorphometric analysis was performed using decalcified and non-decalcified sections. Results: Histological analysis revealed areas of necrotic bone (NcB) occasionally in contact with or completely engulfed by newly formed vital bone (VB) in both AT and AL groups (55.9 ± 27.6 vs. 43.1 ± 20.3, respectively; P = 0.19). Statistically significant larger amounts of VB (27.6 ± 17.5 vs. 8.4 ± 4.9, respectively; P = 0.0002) and less soft connective tissue (ST) (16.4 ± 15.6 vs. 48.4 ± 18.1, respectively; P ≤ 0.0001) were seen for AT compared with AL. No significant differences were observed between the groups regarding both bone-to-implant contact (BIC) and the bone area between implant threads (BA) on the mini-implant biopsies. Conclusion: Allogeneic bone block grafts may be an option in cases where a limited amount of augmentation is needed, and the future implant can be expected confined within the inner aspect of the bone block. However, the clinical impact of the relatively poor graft incorporation on the long-term performance of oral implants placed in AL grafts remains obscure. © 2013 John Wiley & Sons A/S.

Search for supersymmetry in final states with missing transverse energy and 0, 1, 2, or ≥3 b-quark jets in 7 TeV pp collisions using the variable α T

A search for supersymmetry in final states with jets and missing transverse energy is performed in pp collisions at a centre-of-mass energy of s=7 TeV. The data sample corresponds to an integrated luminosity of 4.98 fb-1 collected by the CMS experiment at the LHC. In this search, a dimensionless kinematic variable, α T, is used as the main discriminator between events with genuine and misreconstructed missing transverse energy. The search is performed in a signal region that is binned in the scalar sum of the transverse energy of jets and the number of jets identified as originating from a bottom quark. No excess of events over the standard model expectation is found. Exclusion limits are set in the parameter space of the constrained minimal supersymmetric extension of the standard model, and also in simplified models, with a special emphasis on compressed spectra and third-generation scenarios.[Figure not available: see fulltext.] © 2013 CERN for the benefit of the CMS Collaboration.

Search for heavy quarks decaying into a top quark and a W or Z boson using lepton + jets events in pp collisions at √s = 7 TeV

Results are presented from a search for the pair-production of heavy quarks, QQ̄, that decay exclusively into a top quark and a W or Z boson. The search is performed using a sample of proton-proton collisions at √s = 7 TeV corresponding to an integrated luminosity of 5.0 fb-1, collected by the Compact Muon Solenoid experiment. The signal region is defined using a sample of events containing one electron or muon, missing transverse momentum, and at least four jets with large transverse momenta, where one jet is likely to originate from the decay of a bottom quark. No significant excess of events is observed with respect to the standard model expectations. Assuming a strong pair-production mechanism, quark masses below 675 (625) GeV decaying into tW (tZ) are excluded at the 95 % confidence level.[Figure not available: see fulltext.] © 2013 CERN for the benefit of the CMS collaboration.

Search for supersymmetry in final states with a single lepton, b-quark jets, and missing transverse energy in proton-proton collisions at √s=7 TeV

A search motivated by supersymmetric models with light top squarks is presented using proton-proton collision data recorded with the CMS detector at a center-of-mass energy of √s=7 TeV during 2011, corresponding to an integrated luminosity of 4.98 fb-1. The analysis is based on final states with a single lepton, b-quark jets, and missing transverse energy. Standard model yields are predicted from data using two different approaches. The observed event numbers are found to be compatible with these predictions. Results are interpreted in the context of the constrained minimal supersymmetric standard model and of a simplified model with four top quarks in the final state. © 2013 CERN.

Search for new physics in events with photons, jets, and missing transverse energy in pp collisions at √s =7 TeV

A search for physics beyond the standard model involving events with one or more photons, jets, and missing transverse energy has been performed by the CMS experiment. The data sample corresponds to an integrated luminosity of 4.93 fb-1 of proton-proton collisions at √s =7 TeV, produced at the Large Hadron Collider. No excess of events with large missing transverse energy is observed beyond expectations from standard model processes, and upper limits on the signal production cross sections for new physics processes are set at the 95% confidence level. The results of this search are interpreted in the context of three models of new physics: a general model of gauge-mediated supersymmetry breaking, Simplified Models, and a theory involving universal extra dimensions. In the absence of evidence for new physics, exclusion regions are derived in the parameter spaces of the respective models.[Figure not available: see fulltext.] © 2013 CERN for the benefit of the CMS collaboration.

Search for supersymmetry in pp collisions at √s = 7 TeV in events with a single lepton, jets, and missing transverse momentum

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Periodontal disease reduces water and sodium intake induced by injection of muscimol into the lateral parabrachial nucleus

Objective: Gamma-aminobutyric acid A (GABAA) receptor activation with muscimol in the lateral parabrachial nucleus (LPBN) induces water and 0.3 M NaCl intake. The purpose of this study was to investigate whether a local inflammatory event, such as periodontal disease (PD), is able to alter the effects of muscimol on water and 0.3 M NaCl intake in fluid-replete rats and in rats treated with furosemide (FURO) combined with captopril (CAP) injected subcutaneously. Design: Male Wistar rats were divided into two groups: with PD and those without PD (control condition). Fifteen days after PD, both groups had cannulas implanted bilaterally into the LPBN. Results: In fluid-replete rats without PD, injections of muscimol (0.5 nmol/0.2 μl) into the LPBN induced 0.3 M NaCl and water intake and a pressor response. In fluid-replete rats with PD, a decrease was observed in water intake and pressor response but not in 0.3 M NaCl intake. In control rats with FURO + CAP treatment, injections of muscimol into the LPBN increased 0.3 M NaCl and water intake. In PD rats with FURO + CAP treatment, a decrease was observed in 0.3 M NaCl and water intake after muscimol in the LPBN. Alveolar bone loss and interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) plasmatic concentration were higher in PD rats in comparison with controls. Conclusion: These results suggest that PD is able to reduce the pressor response and the dipsogenic and natriorexigenic effects induced by the activation of GABAA receptors in the LPBN, probably due to the elevation of the plasmatic concentration of pro-inflammatory cytokines IL-6 and TNF-α. © 2013 Elsevier Ltd. All rights reserved.

Search for physics beyond the standard model in events with τ leptons, jets, and large transverse momentum imbalance in pp collisions at √s = 7 TeV

A search for physics beyond the standard model is performed with events having one or more hadronically decaying τ leptons, highly energetic jets, and large transverse momentum imbalance. The data sample corresponds to an integrated luminosity of 4.98 fb-1 of proton-proton collisions at √ = 7 TeV collected with the CMS detector at the LHC in 2011. The number of observed events is consistent with predictions for standard model processes. Lower limits on the mass of the gluino in supersymmetric models are determined. © 2013 CERN for the benefit of the CMS collaboration.

Episode of Low Level Jets in the north and northeast coast of state of Para: a case study of 2002 april 21st to 22nd

Neste estudo descreve-se as características da estrutura vertical de um episódio de Jatos de Baixos Níveis (JBN) ocorrido no litoral do Pará, utilizando-se para tal, dados das radiossondagens de Ajuruteua, Município de Bragança coletados durante o experimento DESMATA (Impacto do Desmatamento Junto ao Litoral Atlântico da Amazônia) realizado no período de 08 a 22 de abril de 2002. Dentre os casos detectados no período chuvoso, selecionou-se um que se manteve por 12 horas com velocidade média de 15m/s e que estava direcionado de Nordeste para Leste, no ponto de máxima velocidade. Os resultados observacionais indicaram que, este JBN localizado no litoral Paraense foi resultado da ação combinada de dois fatores: (1) oscilação inercial e (2) baroclinia superficial. Estes dois fatores combinados sustentaram este JBN com intensidades entre 10 e 13m/s durante o dia e entre 14 e 16m/s durante a noite, localizado a uma altitude média de 800m acima da superfície.

Cortical representation of the horizon in V1 and peripheral scaling in mammals with lateral eyes

In the present investigation we mapped the primary visual area of the South American diurnal rodent, Dasyprocta aguti, by standardized electrophysiological mapping techniques. In particular, we performed a series of mapping experiments of the visual streak in the primary visual cortex. We found that the representation of the visual streak in V1 is greatly expanded, the nasal 10 degrees of the visual streak representation occupies ten times more cortical area than equivalent areas in the central or temporal representation. Comparison of these data with those on the density of ganglion cells in the retina at corresponding locations in the visual field reveal a significant mismatch between these two variables. The nasal representation is greatly expanded along the horizontal meridian in V1 as compared to the central and temporal regions whereas the density of ganglion cells decreases with progression along the visual streak from central region towards the nasal or temporal visual field. A review of the available data reveals that all lateral-eyed mammals exhibit a similar mismatch between the retinal and cortical representation of the visual field, and this mismatches is greater in those species with well defined visual streaks such as rabbit and agouti.

Lateral interactions in visual perception of temporal signals: cortical and subcortical components

The aim of this work was to isolate and investigate subcortical and cortical lateral interactions involved in flicker perception. We quantified the perceived flicker strength (PFS) in the center of a test stimulus which was simultaneously modulated with a surround stimulus (50% Michelson contrast in both stimuli). Subjects were requested to adjust the modulation depth of a separate matching stimulus that was physically identical to the center of the test stimulus but without the surround. Using LCD goggles, synchronized to the frame rate of a CRT screen, the center and surround could be presented monoptically or dichoptically. In the monoptic condition, center-surround interactions can have both subcortical and cortical origins. In the dichoptic condition, center-surround interactions cannot occur in the retina and the LGN, therefore isolating a cortical mechanism. Results revealed both a strong monoptic (subcortical plus cortical) lateral interaction and a weaker dichoptic (cortical) lateral interaction. Subtraction of the dichoptic from the monoptic data revealed a subcortical mechanism of the lateral interaction. While the modulation of the cortical PFS component showed a low-pass temporal-frequency tuning, the modulation of the subcortical PFS component was maximal at 6 Hz. These findings are consistent with two separate temporal channels influencing the monoptic PFS, each with distinct lateral interactions strength and frequency tuning characteristics. We conclude that both subcortical and cortical lateral interactions modulate flicker perception.

Event shapes and azimuthal correlations in Z plus jets events in pp collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for Top Squarks in R-Parity-Violating Supersymmetry Using Three or More Leptons and b-Tagged Jets

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for new physics in events with same-sign dileptons and jets in pp collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Measurement of the production cross sections for a Z boson and one or more b jets in pp collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)