General and oral health-related quality of life among caregivers of Parkinson's disease patients

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Role of the lateral parabrachial nucleus in the control of sodium appetite

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Identification and association of polymorphisms in CAPN1 and CAPN3 candidate genes related to performance and meat quality traits in chickens

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Nutrient enrichment is related to two facets of beta diversity for stream invertebrates across the united states

Beta diversity, the spatial or temporal variability of species composition, is a key concept in community ecology. However, our ability to predict the relative importance of the main drivers of beta diversity (e. g., environmental heterogeneity, dispersal limitation, and environmental productivity) remains limited. Using a comprehensive data set on stream invertebrate assemblages across the continental United States, we found a hump-shaped relationship between beta diversity and within-ecoregion nutrient concentrations. Within-ecoregion compositional dissimilarity matrices were mainly related to environmental distances in most of the 30 ecoregions analyzed, suggesting a stronger role for species-sorting than for spatial processes. The strength of these relationships varied considerably among ecoregions, but they were unrelated to within-ecoregion environmental heterogeneity or spatial extent. Instead, we detected a negative correlation between the strength of species sorting and nutrient concentrations. We suggest that eutrophication is a major mechanism disassembling invertebrate assemblages in streams at a continental scale.

Inverse relaxation effect of azo-dye molecules: The role of the film anisotropy

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Usual interstitial pneumonia and smoking-related interstitial fibrosis display epithelial to mesenchymal transition in fibroblastic foci

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Blood pressure and lipid profile in young women: the role of anthropometric measurement

Body composition has fundamental importance in the quality of life and is a powerful predictor of mortality and morbidity in humans. The identification and monitoring of the amount of body fat have been receiving special attention in aspects related to health promotion, not just for its actions in the prevention and in the control of cardiovascular diseases but also for their induction and association with risk factors, especially in the plasmatic lipid levels and arterial pressure. It was investigated the relationship between body mass index (BMI) and body fat percentage (%BF) by bioelectrical impedance analysis (BIA) with the blood pressure levels (systolic and diastolic) and serum lipids (TC, HDL-c, LDL-c, VLDL-c, TG). In a group of fifty seven women (aged 18 to 26 years old ), obesity was detected in 5 and 19 women by BMI (≥ 30 kg/m2) and %BF (≥ 30%), respectively. BMI and % BF were positively correlated with blood pressure (systolic and diastolic), and highly significant in the obese group by %BF. Moreover, BMI and % BF were significantly correlated with all lipids and lipoprotein fractions VLDL-c and triglyceride, respectively. These results suggest that %BF is a good indicator of “occult obesity” in subjects with normal body mass index. The associated use of BMI and %BF to better evaluate obesity may improve the study of blood pressure levels and serum lipid changes that are commonly associated with obesity.

Infância, família e escola: análise dos significados da Infância e dos Direitos da Criança

This study aimed at analyzing the meanings of Children and Child Rights awarded by the kindergarten children and their educators, parents and teacher. Interest in the subject arose from the participation of the University Extension Project, conducted at the Department of Education, UNESP, Bauru, called The Rights of the Child: ECA in school. Since then, the question arose: to what extent we have visibility of meanings that educators and the child has on the Rights of the Child relating to the specifics of childhood? The research followed the tenets of qualitative research, methodological procedures and adopting the observation in a classroom from kindergarten (K II), semi-structured interview through leisure moments, with the class of aged five years and a questionnaire for family and teacher. The research adopted as reference material, studies of the area of Sociology of Childhood, History of Childhood, Public Policy, Legislation Related to the theme, and an overview of psychogenic to talk about the morality of children. The results showed that parents and caregivers understand childhood as a stage of child development, marked by jokes and fancies, in which the family and the school has an important role in this process. In what concerns the children's rights, there are contradictions in the legal aspects and the situation of children today. The results showed that children's childhood is characterized by recreational activities, and adults are responsible for caring for them. And it comes on the Rights of the Child noted that there is a confusion between rights and duties because they are in a phase of moral heteronomy. The findings indicate the need for wide dissemination on the Statute of Children and Adolescents, especially in preschools in line with families to practice it a new look at childhood, conceiving children as subjects... (Complete abstract click electronic access below)

A concepção do aluno sobre o papel da educação física na escola após a experiência de acampante

Camping alloys the implementation of a broad variety of activities that involves many aspects of the corporal culture of movement. There is much more than fun in games and plays and that’s what we seek to include in the children’s daily routine. The Physical Education professional has as one of its duties to teach these elements, such as the knowledge related to the citizenship formation to its students. Therefore, the participation in camping can contribute to this formation, since the students have the chance to realize the amplitude of Physical Education and change their view on it, even at school. The aim of this research is to investigate after the camping experience, if the students change their conception on the Physical Education role at school. This study has used qualitative methodology consisting on interviews done prior and post the students camping experience at the school . Ten students of both gender, aged between 13 and 15 years old, were interviewed. It was used a script with semi-structured questions. As the main result it has found an unanimity among the students towards the importance of Physical Education: the responsibility for the health and it’s also arisen discussions on cooperation and respect. Although they recognize that the teacher does not discuss these values and attitudes; two students believe that to have changed their view towards school Physical Education after experiencing the activities proposed in the camping. Despite most of the students haven’t changed their concept on school Physical Education, they had the opportunity to see new activities and to think more carefully about the importance of Physical Education classes at school, an opportunity on building a more critical view on the discipline.

Identification and characterization of ISXax2, a TN3-like transposable element potentially related with the virulence and pathogenicity of Xanthomonas citri subsp. citri

Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

Morphological changes of mammalian nucleoli during spermatogenesis and their possible role in the chromatoid body assembling

Chromatoid body (CB) is a typical cytoplasmic organelle of germ cells, and it seems to be involved in RNA/protein accumulation for later germ-cell differentiation. Despite most of the events in mammals spermatogenesis had been widely described in the past decades and the increase in the studies related to the CB molecular composition and physiology, the origins and functions of this important structure of male germ cells are still unclear. The aims of this study were to describe the nucleolar cycle and also to find some relationship between the nucleolar organization and the CB assembling during the spermatogenesis in mammals. Cytochemical and cytogenetics analysis showed nucleolar fragmentation in post-pachytene spermatocytes and nucleolar reorganization in post-meiotic spermatids. Significant difference in the number and in the size of nucleoli between spermatogonia and round spermatids, as well as differences in the nucleolar position within the nucleus were also observed. Ultrastructural analysis showed the CB assembling in the cytoplasm of primary spermatocytes and the nucleolar fragmentation occurring at the same time. In conclusion our results suggest that the CB may play important roles during the spermatogenesis process in mammals and that its origin may be related to the nucleolar cycle during the meiotic cell cycle.

The essential role of annexin A1 mimetic peptide in the skin allograft survival

Immunosuppressive drugs have a critical role in inhibiting tissue damage and allograft rejection.Studies have demonstrated the anti-infl ammatory effects of the annexin A1 (AnxA1) in the regulationof transmigration and apoptosis of leucocytes. In the present study, an experimental skin allograftmodel was used to evaluate a potential protective effect of AnxA1 in transplantation survival. Micewere used for the skin allograft model and pharmacological treatments were carried out using eitherthe AnxA1 mimetic peptide Ac2-26, with or without cyclosporine A (CsA), starting 3 days beforesurgery until rejection. Graft survival, skin histopathology, leucocyte transmigration and expressionof AnxA1 and AnxA5 post-transplantation were analysed. Pharmacological treatment with Ac2-26increased skin allograft survival related with inhibition of neutrophil transmigration and inductionof apoptos is, thereby reducing the tissue damage compared with control animals. Moreover, AnxA1and AnxA5 expression increased after Ac2-26 treatment in neutrophils. Interestingly, thecombination of Ac2-26 and cyclosporine A showed similar survival of transplants when compared withthe cyclosporine A group, which could be attributed to a synergistic effect of both drugs. Investigationsin vitro revealed that cyclosporine A inhibited extracellular-signal-regulated kinase (ERK) phosphory-lation induced by Ac2-26 in neutrophils. Overall, the results suggest that AnxA1 has an essential role inaugmenting the survival of skin allograft, mainly owing to inhibition of neutrophil transmigration andenhancement of apoptosis. This effect may lead to the development of new therapeutic approachesrelevant to transplant rejection.

Supervisão de ensino: estudo descritivo de atos normativos e discussão de termos de visita/acompanhamento

Pós-graduação em Educação Escolar - FCLAR

New ligands of the cellular retinoic acid-binding protein 2 (CRABP2) suggest a role for this protein in chromatin remodeling

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O tutor virtual na formação continuada em educação especial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)