984 resultados para MIÑO, REINALDO


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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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PURPOSE:To investigate the effects of occupational exposure to waste anesthetic gases on genetic material and antioxidant status in professionals during their medical residency. METHODS:The study group consisted of 15 medical residents from Anesthesiology and Surgery areas, of both genders, mainly exposed to isoflurane and to a lesser degree to sevoflurane and nitrous oxide; the control group consisted of 15 young adults not exposed to anesthetics. Blood samples were drawn from professionals during medical residency (eight, 16 and 22 months of exposure to waste anesthetic gases). DNA damage was evaluated by comet assay, and antioxidant defense was assessed by total thiols and the enzymes glutathione peroxidase (GPX), superoxide dismutase (SOD) and catalase (CAT). RESULTS:When comparing the two groups, DNA damage was significantly increased at all time points evaluated in the exposed group; plasma thiols increased at 22 months of exposure and GPX was higher at 16 and 22 months of exposure. CONCLUSION:Young professionals exposed to waste anesthetic gases in operating rooms without adequate scavenging system have increased DNA damage and changes in redox status during medical residency. There is a need to minimize exposure to inhalation anesthetics and to provide better work conditions.

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The objective of this work was to study the floristic composition and structure of the Cerrado (Brazilian savannah), focusing on the tree and shrub strata. A total of 30 plots (10x10m) were set up, distributed in 10 contiguous blocks where individuals with a minimum PBH of 10 cm were sampled. A total of 1,107 individuals were sampled. Such individuals belonged to 33 families and 88 species, showing high values of richness. Total basal area and total density were respectively 6,651m² and 3690 individuals per hectare. The values of diversity (3.868 nats/individual) and evenness (0.86) show high heterogeneity and low ecological dominance. The most important species were Qualea grandiflora Mart., Lafoensia pacari St. Hil., Magonia pubescens St. Hil. and Qualea parviflora Mart., which together represented 57.7% of VI.

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Uberaba municipality, Western Minas Gerais State, has a great geotouristic potential, regarding its geological heritage. The igneous rocks from Serra Geral Formation are found in 12 points, highlighting Ponte Alta (40 meters) and Peirópolis III (7 meters) waterfalls. The sedimentary rocks from Uberaba Formation were described in 11 points, especially Giovane Cave and Waterfall (12 meters). In Marilia Formation sedimentary rocks, the Caieira outcrop (three-meter cave with stalactites and stalagmites) and Vale Encantado Waterfall (8 meters) can be pointed out, among other 8 spots. After the geodiversity assessment, an environmental diagnosis was conducted throughout the potential geotourism attractions, by using the Visitor Impact Management Method. The results indicate that only Vale Encantado Waterfall presents a moderate impact, the least when compared to 22 other sites, exhibiting high or worrisome impact, and 7 with very high impact. In addition to setting the management strategies, and monitoring the environmental impact indicators, this work provides the basis so that activities in the potential Geopark of Uberaba (MG) can be conducted with environmental responsibility and / or geoconservation.

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Os conceitos e aplicações da ergonomia estão em constante discussão no âmbito acadêmico, caracterizando um corpus de conhecimento de grande expressividade para a própria ciência ergonômica e demais áreas tecnológicas correlatas, a saber: engenharias, design, arquitetura, e outras. Entre as demandas para ampliar as análises em torno dessa disciplina apresenta-se sua evolução histórica, a qual está completa de controvérsias e discussões. De fato, há ainda uma grande dificuldade em relatar suas etapas históricas dentro do âmbito geográfico e a participação de seus precursores nessas fases. Assim, o propósito dessa coletânea foi o de reunir os estudos realizados pelos alunos da linha de pesquisa ergonomia, associados ao Laboratório de Ergonomia e Interfaces - LEI, no Programa de Pós-graduação em Design - PPGDesign, da Faculdade de Arquitetura, Artes e Comunicação da Universidade Estadual Paulista, e apresentar subsídios para ampliação da discussão e reflexão evolutiva da ergonomia. Os primeiros capítulos relatam os precursores da ergonomia, com destaque para Leonardo da Vinci e seus estudos na área da anatomia; Bélidor, Patissier e suas contribuições para a organização do trabalho; o Taylorismo e os aspectos da organização científica do trabalho, bem como a contribuição de Jules Amar nesse âmbito. Os demais capítulos abordam a origem e evolução da ergonomia na Europa, na Rússia (ex URSS), Estados Unidos da América, América Latina e Brasil, com ênfase a criação de laboratórios e associações não governamentais. De modo geral, os estudos ora apresentados preenchem lacunas ainda existentes dentro da ergonomia e procuram estabelecer um elo de ligação para a continuidade futura das pesquisas na área

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Background: Little information on the factors influencing intraoperative cardiac arrest and its outcomes in trauma patients is available. This survey evaluated the associated factors and outcomes of intraoperative cardiac arrest in trauma patients in a Brazilian teaching hospital between 1996 and 2009.Methods: Cardiac arrest during anesthesia in trauma patients was identified from an anesthesia database. The data collected included patient demographics, ASA physical status classification, anesthesia provider information, type of surgery, surgical areas and outcome. All intraoperative cardiac arrests and deaths in trauma patients were reviewed and grouped by associated factors and also analyzed as totally anesthesia-related, partially anesthesia-related, totally surgery-related or totally trauma patient condition-related.Findings: Fifty-one cardiac arrests and 42 deaths occurred during anesthesia in trauma patients. They were associated with male patients (P<0.001) and young adults (18-35 years) (P = 0.04) with ASA physical status IV or V (P<0.001) undergoing gastroenterological or multiclinical surgeries (P<0.001). Motor vehicle crashes and violence were the main causes of trauma (P<0.001). Uncontrolled hemorrhage or head injury were the most significant associated factors of intraoperative cardiac arrest and mortality (P<0.001). All cardiac arrests and deaths reported were totally related to trauma patient condition.Conclusions: Intraoperative cardiac arrest and mortality incidence was highest in male trauma patients at a younger age with poor clinical condition, mainly related to uncontrolled hemorrhage and head injury, resulted from motor vehicle accidents and violence.

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Forty-five non-lactating, pregnant Holstein animals (18 heifers and 27 multiparous cows; BW = 561 +/- 114 kg; BCS = 2.9 +/- 0.3; days pregnant = 110 +/- 56 d) were stratified by initial BW and BCS, and randomly assigned to receive daily (as-fed basis) 0.50 kg of ground corn plus 0.22 kg of kaolin (CON), calcium salts of saturated fatty acids (SFA) or polyunsaturated fatty acids (PF) for 14 d. Blood samples were collected on days 0, 7 and 14, immediately prior to (0 h) and 3, 6, 9 and 12 h after feeding, to determine the serum concentrations of P 4 and insulin. No treatment effects were detected for serum concentrations of P 4 (5.52, 6.13 and 5.63 +/- 0.41 ng/mL for CON, SFA and PF, respectively). No treatment effects were detected for serum concentrations of insulin (11.5, 10.5 and 10.1 +/- 1.43 mu IU/mL for CON, SFA and PF, respectively). Heifers had greater serum concentrations of P 4 than multiparous cows (6.35 vs. 5.16 +/- 0.42 ng/mL), but lower serum concentrations of insulin (7.0 vs. 14.4 +/- 1.49 mu IU/mL). Feeding 0.22 kg of calcium salts of polyunsaturated fatty acids is not sufficient to increase the serum concentrations of P 4 and insulin of non-lactating, pregnant dairy cows.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)