884 resultados para Järvelä, Elina


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This report discusses how the current EU credit reporting systems meet the demands of the different stakeholders in the credit granting and management process, and what is needed to improve these systems. As credit reporting is a tool for responsible lending and for ensuring financial inclusion of consumers, it argues that the needs of EU credit markets and consumers should be the basis for assessing the current regulation and its functionality. How a creditor assesses the risk and the creditworthiness of a customer is at the core of successful and safe crediting. Facilitating this assessment process, within the boundaries of data protection laws, is a key building block for making well-informed credit decisions.

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Despite the emergence of a critical debate against the EU-imposed austerity measures both at the level of the political elites and on the street, this EPIN Commentary by two Spanish political scientists based in Barcelona finds no sign that the upcoming European elections will have a more European focus than any of the previous ones. While there is no anti-European discourse among the Spanish mainstream political parties, they report that public trust in the European institutions is plummeting and Spanish turnout in European elections has been dropping in the last few years. In the authors’ view, the main reason for this is the low level of awareness of the functioning of the European Parliament but some responsibility also lies with the Spanish political parties and the way they deal with the electoral campaign to mobilise the discontented voters, who consider unemployment and the economic situation as the two most important issues that the country is facing at the moment.

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One to two percent of all children are born with a developmental disorder requiring pediatric hospital admissions. For many such syndromes, the molecular pathogenesis remains poorly characterized. Parallel developmental disorders in other species could provide complementary models for human rare diseases by uncovering new candidate genes, improving the understanding of the molecular mechanisms and opening possibilities for therapeutic trials. We performed various experiments, e.g. combined genome-wide association and next generation sequencing, to investigate the clinico-pathological features and genetic causes of three developmental syndromes in dogs, including craniomandibular osteopathy (CMO), a previously undescribed skeletal syndrome, and dental hypomineralization, for which we identified pathogenic variants in the canine SLC37A2 (truncating splicing enhancer variant), SCARF2 (truncating 2-bp deletion) and FAM20C (missense variant) genes, respectively. CMO is a clinical equivalent to an infantile cortical hyperostosis (Caffey disease), for which SLC37A2 is a new candidate gene. SLC37A2 is a poorly characterized member of a glucose-phosphate transporter family without previous disease associations. It is expressed in many tissues, including cells of the macrophage lineage, e.g. osteoclasts, and suggests a disease mechanism, in which an impaired glucose homeostasis in osteoclasts compromises their function in the developing bone, leading to hyperostosis. Mutations in SCARF2 and FAM20C have been associated with the human van den Ende-Gupta and Raine syndromes that include numerous features similar to the affected dogs. Given the growing interest in the molecular characterization and treatment of human rare diseases, our study presents three novel physiologically relevant models for further research and therapy approaches, while providing the molecular identity for the canine conditions.

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Fil: Tranchini, Elina. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

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En el presente trabajo se pretende comparar y distinguir, por medio análisis de audiovisuales diferentes y épocas de producción también distintas, como dos obras documentales plantearon su mirada y visión acerca de la localidad de Iruya. Con la representación de dos realizadores por un lado, Jorge Prelorán con su film etnográfico Iruya del año 1968 y por otro lado, Ulises de la Orden en la subjetividad del documental: Rio Arriba, Una Historia de terrazas, ingenios y volcanes, encontraron en Iruya, un paisaje transcultural como estrategia de resistencia más allá del audiovisual, que incorpora lo local y lo global, que busca solidaridades trasnacionales a través de su hibridismo, fruto de la ruptura de las fronteras culturales y la exaltan una vez más como una tierra de contrastes. Buscando con la comparación y contextualización del cine documental, entenderlos a ambos films como portavoces de la memoria a la vez que el discurso cinematográfico se convierte en narrador de la identidad e historia cultural de la comunidad de Iruya

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Fil: Tranchini, Elina. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

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Fil: Turkenich, Magalí. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.