Proliferação e Morte Celular (Apoptose) avaliadas em ratos Lewis após tratamento com mistura de praguicidas em baixas doses

The use of pesticides in Brazil has intensified over the years. And since 2009 it was ranked as the largest market for pesticides worldwide. The consequential diffuse contamination of the environment is therefore due to the increasing number of chemicals of different classes, origins and modes of action. Little is known about the action of pesticides on human health in situations of co-exposure. Possible toxic effects are not restricted to agricultural and industrial workers, but also the general population that may be exposed continuously to its residues in food and water. Although these pesticides are mostly present in the environment at low doses, it must be considered that possible cumulative or synergistic effects may occur when there are concurrent or sustained exposure for two or more of these agents, which can lead to late manifestation of subclinical damages, sometimes irreversible. Thus, the specific objective of this study was to assess the effect of carcinogenesis promotion of a mixture of pesticides at low doses and analyze the phenomena of cell proliferation and apoptosis in rat liver. A total of 50 male Lewis rats was separated into 5 groups for 8 weeks in a medium term hepatocarcinogenesis model. The three different classes of pesticides (dieldrin, dicofol, endosulfan, dichlorvos and permethrin), whose residues were detected by ANVISA during the period from 2001 to 2005 in tomatoes cultures, were added to the feed of rats initiated to hepatocarcinogenesis with diethylnitrosamine (DEN- 200mg/kg ip). We used two different mixtures, one with no toxic effects at doses (MEX1) referring to the NOEL (no-observed-effect level) and another at doses LOEL / LEL / LOAEL (Lowest-observed-effect level / Lowest-effect level / Lowest -observed-adverse-effect level), to the installation of adverse effects (MEX2), derived from chronic studies. All animals ...(Complete abstract click electronic access below)

Contagem automatizada de veículos utilizando segmentação estatística

In this work was developed a program capable of performing automatic counting of vehicles on roads. The problem of counting vehicles is using expensive techniques for its realization, techniques which often involve manual counting or degradation of the pavement. The main motivation for this work was the importance that the vehicle counting represents to the Traffic Engineer, being essential to analyze the performance of the roads, allowing to measure the need for installation of traffic lights, roundabouts, access ways, among other means capable of ensuring a continuous flow and safe for vehicles. The main objective of this work was to apply a statistical segmentation technique recently developed, based on a nonparametric linear regression model, to solve the segmentation problem of the program counter. The development program was based on the creation of three major modules, one for the segmentation, another for the tracking and another for the recognition. For the development of the segmentation module, it was applied a statistical technique combined with the segmentation by background difference, in order to optimize the process. The tracking module was developed based on the use of Kalman filters and application of simple concepts of analytical geometry. To develop the recognition module, it was used Fourier descriptors and a neural network multilayer perceptron, trained by backpropagation. Besides the development of the modules, it was also developed a control logic capable of performing the interconnection among the modules, mainly based on a data structure called state. The analysis of the results was applied to the program counter and its component modules, and the individual analysis served as a means to establish the par ameter values of techniques used. The find result was positive, since the statistical segmentation technique proved to be very useful and the developed program was able to count the vehicles belonging to the three goal..

Avaliação dos danos por fluência da serpentina da caldeira da REVAP

The determination of the remaining life of equipment operating at high temperatures has been a great challenge for their owners. The use of safety factors, often conservative, makes the replacement of equipment or of its components at the end of the life of design gets financially unviable. This study aimed to estimate the remaining life of the serpentine of the secondary superheater of one of REVAP’s boilers (Henrique Lage Refinery), through accelerated creep tests and comparison of the results with the techniques based on microstructure and hardness. When conducting a proper assessment it’s possible to increase the equipment reliability, ensuring operational continuity and physical integrity. The tests showed a minimal residual life of 12.7 years (111,252 hours), longer than the design life (100,000 hours), even after a period of operation of approximately 250,000 hours, confirming the conservatism of the project. The techniques based on microstructure and hardness did not show good correlation with the creep test, decreasing the reliability of these techniques in determining the residual life

Proposta de elaboração de carta de sensibilidade ambiental aplicada a postos de combustíveis em Rio Claro-SP

Leaking of hydrocarbon in fuel underground storage tanks constitute object of concern for urban environmental management, because therefore they provoke damages to the physical, biological and socioeconomic environment. Though laws that regulate this essential activity exist, aiming at to prevent contamination with hydrocarbon, we observe that this still happens. This fact evidences that the selection of places for installation of gas stations has not considered the characteristics of the natural environment, implying in more critical consequences associated to the leaking. The objective of this work is to elaborate a chart applied to the gas stations in Rio Claro/SP. The determination of the Index of Environmental Sensitivity for elaboration of such chart was carried through breaking the selection of factors of Environmental Sensitivity of physical, biological and socioeconomic environment. The balance of these factors was given by means of Ad hoc consultation. The crossing of the information was carried through using the method of overlapping of overlays. The result is a chart that shows us areas with classes of high, middle and low Environmental Sensitivity. One gives credit that this type of material can be used as criterion in the selection of adjusted areas for installations of new gas stations and management of the already installed gas stations. The diagnosis of the current situation of the gas stations in the area and recommendations had also been elaborated.

Análise da influência da iluminação de rodovias federais com a redução do número de acidentes

The increasing rate of traffic accidents, followed by the high rate of mortality due to these occurrences, favored to the classification of traffic accidents as a public health problem in Brazil. These accidents consume a significant portion of Gross Domestic Product (GDP), especially related to the victims. Considering this scenery with many tragedies and resources being spent only in the end, this paper seeks to examine the influence of federal highways lighting by reducing the number of accidents. Federal Highways sections that received lighting were taken up for study, therefore a survey of statistical data has been raised considering the accidents before and after the route had been illuminated. Taking advantage of the results obtained, an economic analysis has been made considering the amounts consumed by traffic accidents versus the values required for the installation of lighting on highways

Avaliação da influência do substrato utilizado na qualidade e quantidade das parcelas de água escoada, percolada e armazenada em três estruturas experimentais de telhado verde extensino

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estabelecimento de rotinas de operação e orientações de manutenção para a planta termelétrica do DEN/FEG/UNESP

Steam generation plants have several industrial applications, being important for the national and global energetic matrix. Operational knowledge of steam plants is extremely important to forming a Mechanical Engineer. The facilities from Faculty of Engineering of Guaratingueta have a no operated steam pilot plant, named Thermal Machine Lab. Nowadays, the Energy Department from the faculty cannot explore this lab for its classes, even being essential to consolidate the theoretical concepts with tests simulating industrial applications. The goal of this project was to restore the operational condition of equipment of steam laboratory by fixing the equipment, and creating operational scripts for them. In a close future this lab could be used for classes, research and other applications

Subsídios para implantação de trincheiras de infiltração na área urbana de Rio Claro/SP

The purpose of this work is to study the theme “infiltration trenches” in some of its main aspects, such as sizing methods and parameters related to this, in order to subsidize the installation of these structures in the urban area of Rio Claro/SP. For purposes of sizing, the “rain-envelope method” was used for its simplicity and direct application from the local characterization data and the IDF (intensity-duration-frequency) curve data. The method bases on the determination of the tributary volume of input and output device. The curve of values accumulated over time of the volumes tributaries to the device, which is built on the flow rates obtained from the local IDF curve, is compared with the value curve of his effluent volumes determined from the flow characteristics obtained from the infiltration soil. The maximum difference between the curves is the volume sizing. Five locations were chosen in the urban area of Rio Claro for implementation of these devices, considering the soil type, hydraulic conductivity of each area and lot size according to the Master Plan of Rio Claro. This work also presented an estimated reduction of the runoff in urban lots by using infiltration trenches.

Gama Câmara CZT: alteração de paradigmas em aquisição de imagens de medicina nuclear

Nuclear medicine is a medical specialty related to imagery that deals with imaging techniques, diagnosis and therapy, allowing observing the physiological state of tissues noninvasively by marking the molecules participating of these physiological processes with radioactive isotopes, thus creating the called radionuclides. The image of a radionuclide is one of the most important applications of radioactivity in nuclear medicine. The equipment’s of nuclear medicine imaging use the principle of radiation detection, turning it into an electrical signal which, through specific algorithms, allows forming tomographic images that provide information about the functional status of organs. New detection systems have been developed for tomographic acquisitions using solid state detectors. These devices use crystals of cadmium zinc telluride (CdZnTe). Some of the advantages of this detector are a significant improvement of signal to noise ratio, the increased spectral and spatial resolution, which in sum, result in greater clarity of the images obtained, opening new perspectives for imaging protocols previously unattainable. In contrast, all other gamma-cameras equipped with vacuum tubes have remained relatively unchanged for nearly fifty years. In these gamma-cameras, the images are obtained using two steps significantly less efficient: the gamma rays are converted to light through a first device, and then the light is converted into an electrical signal through a second device. One of functions the Medical Physicist is related to the quality control of equipment. This control ensures that the information and images provided are true and thus credible to be used in medical reports. To perform this type of analysis the physicist must understand the performance characteristics and operation of all equipment of the department concerned; besides, in the absence of specific legislation, proposing...(Complete abstract click electronic access below)

Cor do solo na caracterização de áreas específicas de manejo para cultura do café

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Proposta de metodologia para aplicação de eficiência energética em uma usina hidrelétrica

Pós-graduação em Engenharia Mecânica - FEG

Os desdobramentos e conflitos da criação do Parque Estadual Ilha do Cardoso sob a ótica do modelo GTP (Geossistema – Território- Paisagem)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Memórias docentes sobre o início da UNESP em Presidente Prudente: busca por meio de imagens (1975-1980)

Pós-graduação em Educação - FCT

Gestão da Manutenção Centrada na Confiabilidade em Pontes Rolantes

The objective of this work is to perform a study applying the methodology of Reliability Centered Maintenance - MCC to a group of cranes belonging to Amsted -Maxion in Cruzeiro - SP. The work consists of a presentation of maintenance, the reasons why more and more people worry about maintenance, making a presentation on the types of maintenance, its peculiar characteristics and then do a study where you identified the functionality required by the equipment under study, identified failure modes and their probable causes, and then detail the effects and consequences of these failures. With that evaluate the criticality of these failures and identify the most significant consequences that affect safety, availability or cost of equipment operation and allow a selection of the most appropriate tasks for the identified failure modes. We will also present best crane equipment, its main components, verify that there was or not improvement in the machine after the application of MCC and make a current analysis of maintenance in Amsted -Maxion

Controle de Acesso utilizando Arduino, banco de dados MySQL e LabVIEW

The search for more reliable security systems and information management of these systems is leading to a growing progress in new technologies investments that allow the implementation of equipment with a high level of reliability, but also have an agile and practical operation. This led people to turn increasingly looking for home automation systems, enterprise and industry for the automation and integration of their systems. The identification by radio frequency is very widespread today for ensuring both agility in handling records data, the reliability of their identification systems, which are increasingly advanced and less susceptible to fraud. Attached to this technology, the use of the database is always very important for the storage of information collected, the area where the MySQL platform is widely used. Using the open source Arduino platform for programming and manipulation of RFID module and LabVIEW software for the union of all these technologies and to develop a user-friendly interface, you can create a highly reliable access control and agility places a high turnover of people. This project aims to prove the advantages of using all these technologies working together, thus improving a flawed system effectively safety, cheaper and quicker