Ocorrência de microrganismos periodontopatogênicos em pacientes com dependência química

Drug addiction won dramatic aspects in terms of its dimensions and the effects that it imposes. These chemical agents are able to reduce the immune reactivity and tissue repair, and enhance microbial aggression, aggravating the destruction of the periodontium and other side effects. This study aimed to evaluate the presence of key periodontal pathogens in the mouth of drug addiction patients, comparing it with individuals who do not exhibit this dependence, as well as assess the influence of oral conditions on the occurrence of such microorganisms. For this purpose, data on systemic health conditions, socioeconomic, patterns of licit or illicit drug consumption of 100 patients with chemical dependency kept in rehabilitation clinics and an equal number of non-dependent patients, who formed the control group were obtained. Intra and extraoral clinical examinations were performed and samples of supragingival and subgingival biofilm, saliva and mucous membranes were collected. The presence of the targeted microorganism was assessed by polymerase chain reaction (PCR). It was found that Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola showed close correlation with bone loss and gingival bleeding in drug addiction dependents and control group, but the oral mucous membranes and saliva of addicts showed higher occurrence of these pathogens.

Characteristics, complexation and analytical methods of darunavir

What is it? Darunavir is a protease inhibitor used in the treatment of HIV infection. It is an important drug of therapy cocktail for patients infected with the virus. On the market there are darunavir ethanolate tablets of 75, 150, 300, 400, 600 and 800mg, because this is the most stable form. It is commercialized by Janssen-Cilag with the name PrezistaTM. Why we started? This drug has low water solubility and poor bioavailability, therefore requires administration in doses relatively high to the success of the therapeutic effect. The complexation of drugs by using cyclodextrin is welcome in this respect to improve the solubility and hence increase the dissolution rate of poorly soluble drugs. A monograph about this compound has not been described, thus it is an extremely important quality control of darunavir to demonstrate its effectiveness and safety. What we did? Some existing analytical techniques have been discussed in this manuscript, focusing on bioanalytical and pharmaceutical quality control applications. What we found? This review showed the published analytical methods reported for the determination of darunavir and discuss about its characteristics and complexation with cyclodextrin.

Development and validation of a rapid turbidimetric assay to determine the potency of ampicillin sodium in powder for solution for injection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influence of Darunavir: β-cyclodextrin complex on the solubility of Darunavir

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Insights into the swelling process and drug release mechanisms from cross-linked pectin/high amylose starch matrices

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A stability-indicating LC method for difloxacin in the presence of degradation products

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Development and validation of infrared spectroscopy method for the determination of darunavir in tabets

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A segunda tela na tv digital brasileira: um estudo dos processos midiáticos interativos

Pós-graduação em Comunicação - FAAC

Social TV Unesp: proposta de aplicativo em segunda tela com ênfase em modelo de negócios para TV Universitária UNESP

The audiovisual market carefully observes a tendency in television consumption habit: viewers are increasingly watching television content while surfing the internet through mobile devices like tablets, smartphones and laptops. Known as second screen, viewers interact simultaneously across these devices, sharing information about the programming on social networks, seeking additional information about the contents well aired, in addition to being likely to purchase products and services on platforms of mobile-commerce persuaded by the scheduling of programming through commercials. Given this, the aim of this article is to propose and prototyping an application visually in second screen with emphasis on business model with possible application on TV Unesp, where the viewer to interact with the programming through the application is exposed to previously scheduled ads, links to mobile-commerce and posts indicating purchase suggestions.

A TV no ecossistema dos onívoros digitais

A quick setup of the digital environment that occurs in these first decades of the twentyfirst century has involved the use of electronic devices for consume content both at home, at work and on the go (ComScore, 2011). The emergence of this vast multiplatform digital landscape impels to know of individual and complementary use of these devices with ubiquitous nature or not. The widespread adoption of smartphones, tablets and other connected devices via internet makes users / consumers of these devices to feed a diet based on a constant flow of digital content across different platforms. The objective of this paper is to describe the role of television in the context of the Media Ecology which is established by the "digital omnivores" a new group of consumers whose name, according Canavilhas (2013, p.03), "is related with the platforms that consumers use to access the Internet, but also to the type of individual and multiplatform consumption they do.”

O confisco sem condenação penal como medida de recuperação dos bens e valores instrumentos ou produtos da lavagem de ativos

Pós-graduação em Direito - FCHS

Gênero, masculinidades e alcoolismo na modernidade: a Revista Illustração Brasileira, as comemorações do Centenário da Independência e a as elites urbanas cariocas no início do Século XX

Pós-graduação em Ciências Sociais - FFC

Aritmética por apps

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Uma análise do ensino de língua inglesa por meio do uso das Tecnologias Digitais da Informação e Comunicação

Pós-graduação em Educação - FFC

Tecnologias de Informação e Comunicação (TICs) e literatura, uma aposta notável

The aim of this study was to develop a qualitative research of bibliographic nature, in order to verify how has been the use of new Information and Communication Technologies (ICTs) and literary reading in early childhood education.. It is believed to be necessary for children, since their early childhood, to, be in contact with various literary works of aesthetic value, which will enable them to understand this particular literary language - and the imagery that comes with it - what can instigate appreciate literature and get the reading habit. The use of ICTs by children beyond the use of games and watching stories on computers, tablets and smartphones, for example, for the production of videos and slides or creating stories, enable new experiences of redesigning and construction of knowledge and culture. The idea for this research came from reading the numerous texts that deal with the need to understand the child as an active subject in the construction of culture and society, rather than as receiving reproductive and cultural orders (CRIANÇAS, 2012). In this sense, in addition to the newsletters Equity For Children: Latin America (CRIANÇAS, 2012), the understanding of childhood and child in the works of Walter O. Kohan (2005; 2006) supports this study. This research proposal was also based on authors and documents that point to the need to promote, since the first stages of Basic Education, the literary reading as a means of enjoyment and emancipation (LAJOLO 2001a; Barthes, 2007; FILIPOUSKY, 2009; BRAZIL, 2010; MACHADO, 2011; VASQUES, 2013), and an education connected to the technological advances of the twenty-first century (BRAZIL, 1997, CHAVES, 1998; DEMO, 2008)