949 resultados para Human Development


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Recibido 15 de marzo de 2012 •  Corregido 21 de octubre de 2012 • Aceptado 07 de noviembre de 2012 El presente documento plantea la necesidad de que la sociedad contemporánea posea mayores y mejores conocimientos sobre sexualidad, con miras a una vivencia efectiva de esta dentro de un marco de respeto a la biografía sexual del ser humano y fundamentados en la ética relacional. Para ello se apuesta por una educación sexual integral, democrática, tolerante y abierta, dentro de los procesos educativos a lo largo de todas las etapas evolutivas del ser humano. Uno de los sectores profesionales llamados a desarrollar este tipo de educación es el colectivo de orientadores y orientadoras. Para dicha acción, requieren conocer cuáles fueron los modelos o formas de abordaje con los que se educaron y que han marcado su hacer en dicha temática. Esto permitirá que la persona profesional en orientación se dé a la tarea de evaluar, fortalecer o aprender nuevas competencias en el campo personal, actitudinal, conceptual y en cuanto a la visión sobre la diversidad de las personas con quienes trabaja; así como en el campo procedimental, las estrategias y técnicas de intervención orientadora en sexualidad, que incidan en su labor profesional.

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This paper provides a complete description of the Commercial Education Professional Competency Profile that resulted from the curricular diagnosis of the Licenciatura en Educación Comercial , at the Universidad Nacional, Costa Rica.  The methodological strategy used relies on the principles of research on education. Upon expert validation, written questionnaires were applied to first-year students, students of the licenciatura, practicing professionals and employers. The objective was to describe a particular education situation. Data was analyzed according to two categories: intentions/principles and scope/development. The findings resulted in the characteristics of the Commercial Education professionals, i.e. characteristics related to the discipline, characteristics related to the administrative management of teaching, specific and general characteristics of education and pedagogy, and characteristics associated to human development. Based on those criteria, on the curricular requirements of the information sources and on the curricular perspectives of the Academic Unit, ideas were put into practice to build the competency profile. The ideas proposed comprise the curricular fundamentals of the educational project on which the profile is set out, which include the subject of the study program, the global competency or training goal, the generic competencies as cross-cutting approaches, as well as the –pedagogical and disciplinary− specific competencies. The specific competencies of the discipline are focused on four competency areas: document production, organizational support, technological resources and information management.(1) Translator’s Note: One-year post-Bachelor study program in Commercial Education.

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Resumen  Los sistemas de indicadores en materia de derechos económicos, sociales y culturales han tenido un vertiginoso avance en los últimos tiempos en el seno de la Organización de las Naciones Unidas. La justiciabilidad de los derechos citados ha presentado sendos problemas debido a que el artículo segundo del Pacto Internacional de Derechos Económicos, Sociales y Culturales establece que depende de aspectos tales como los recursos disponibles del Estado, la progresividad en la implementación de políticas, entre otros. Por lo tanto, no se le han asignado a tales derechos, un carácter exigible y esta situación ha provocado que su vigencia sea limitada. Precisamente, este ensayo pretende demostrar cómo se ha revertido esta concepción y a través de los sistemas de indicadores desarrollados para diferentes derechos humanos se pueden obtener prestaciones mínimas, que deben cumplir los Estados, para satisfacer las demandas de alcance general.Palabras clave: derechos económicos, sociales y culturales, Organización de las Naciones Unidas, justiciabilidad, progresividad, indicadores de resultado, modelo de indicadores, desarrollo humano.AbstractIndicator systems in terms of economic, social and cultural rights have had a rapid development lately within the United Nations Organization. The justiciability of these rights has presented problems, mainly because of the second article of the International Covenant on Economic, Social and Cultural Rights states that it depends on aspects such as available resources of the State, the progressivity in the implementation of policies, etc. Therefore, these rights have not been given a mandatory character, and this has led to their limited effect. Precisely this essay intends to demonstrate how this conception has been reversed, and how, through the systems of indicators developed for different human rights, minimum benefits are available for the States to meet the demands of general application.Keywords: economic, social and cultural rights, Organization of the United Nations, Justice, output indicators, indicators model, human development.

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Se desarrolla un marco teórico de la seguridad comunitaria al definirla a partir de la evolución que ha tenido el tema de la seguridad comunitaria a partir de la adopción del enfoque más amplio de la seguridad humana de los habitantes como base y eje de las políticas públicas, de donde nace un nuevo conjunto de prioridades para la erradicación de los factores de riesgo social asociados o que son proclives a la violencia y la comisión de delitos, tales como la deserción escolar, el desempleo, la violencia en todas sus formas, la inequidad de género y diversidad social, la falta de cohesión social, las migraciones, internas o externas, forzadas por las condiciones de vida. El enfoque se basa en un nuevo modelo criminológico que está sustentado en el marco de los derechos humanos, la seguridad humana y el modelo de control social democrático para formar un modelo de desarrollo humano sostenible, por tanto la prevención sustentada en políticas públicas para la seguridad humana, la participación comunitaria y el nuevo rol de la policía comunitaria.It develops a theoretical framework for defining the community from the developments that have taken the issue of community safety from the adoption of the broader approach to human security of people as the basis and focus of public policy, arises where a new set of priorities for the eradication of social risk factors that are associated with or prone to violence and committing crimes, such as school dropouts, unemployment, violence in all its forms, gender inequity and social diversity, lack of social cohesion, migration, internal or external, forced by the conditions of life. The approach is based on a new criminological model that is based on the framework of human rights, human security and control model to form a social democratic model of sustainable human development, thus preventing sustained public policies for security human, community involvement and the new role of community police.

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ResumenLos derechos humanos y el desarrollo humano comparten la misma visión y objetivo: garantizar la libertad, el bienestar y la dignidad de todas las personas del mundo. Para alcanzar un desarrollohumano alto es necesario el respeto y el ejercicio eficiente de los derechos humanos, como el acceso a la educación, a los servicios de salud, a la alimentación, a un trabajo dignoy bien remunerado, a la participación activa de las decisiones económicas, entre otros. Al mismo tiempo, es importante tener un nivel de desarrollo suficiente para proporcionar y garantizarlos derechos humanos más fundamentales. En este artículo se presenta un análisis de la situación de los derechos humanos y el desarrollo humano en México. Se utilizan informes e índices de diferentes instituciones, examinando la situación específica de algunos estados. Los resultados indican que aunque México es considerado como un país de desarrollo humano “alto”, no necesariamente ha implicado que el nivel de vida de toda su población sea mejor ytampoco ha garantizado el respeto y ejercicio eficiente de los derechos humanos.Palabras clave: derechos humanos, desarrollo humano, derecho al desarrollo, México. AbstractHuman rights and human development share common visions and goals: to ensure the freedom, well-being and dignity of all the people. The achievement of a high level of human development requires both respect for and the effective exercise of fundamental human rights, including the right to: education, healthcare services, adequate food, dignified and justly remunerated work, and meaningful participation in economic decision-making, among other fundamental rights. The provision for and protection of the most basic human rights and the achievement of an acceptable level of human development are interdependent. This paper presents an analysis of human rights and the human development situation in Mexico. Reports and indices sourced from various institutions are cited and the specific conditions that exist in some Mexican states are evaluated. The results show that although Mexico has a high level of human development, it does not implies that the standard of living of all of its citizens has improved or that respect for and the effective exercise of human rights has accompaniedthis development in Mexico.Keywords: human rights, human development, right to the development, Mexico.

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This thesis is an interdisciplinary piece of academic research, situated within Critical Theory but engaging with other disciplines, mainly Political Economy and Politics, to tackle the topic at hand; sovereign debt crises. The thesis deals with the Problem of Debt and, more specifically, the Problem of Prolonged Sovereign Debt Crises, which is described in this thesis as the phenomenon of the “Debt Trap”. The specific question that will occupy us in this thesis is why countries appear unable to exit these prolonged debt crises. By exiting a debt crisis, we mean here a state of affairs in which a country has managed to render its debt sustainable, regain its democratic sovereignty, achieve economic recovery and, what is more, mitigate adverse effects of the crisis, especially in what human development, social inequality and poverty rates are concerned. This question is tackled through the use of an interdisciplinary approach that combines critical theory perspectives -which are grouped in two paradigms, the Subjectivity paradigm and the genealogies of Capitalism paradigm- with financialisation literature. The purpose is to form an interdisciplinary intellectual framework that will allow us to analyse with a critical perspective the two case studies of the Greek crisis from 2009 to 2015 and the Argentinean crisis from 1983 to 2005. The aim of the thesis is to develop a theoretical framework that allows us to deconstruct the various ideological approaches to these two particular cases of Debt traps, including neoclassical and neoliberal approaches, Conservative and Keynesian approaches and uncover the political, economic and class relation that underpin the prolonged crises that the two countries have experienced.

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In the light of Gary Becker's economic theory of the family, considers how economic cost and benefit factors can influence the size of families that parents decide to have. Some support for the importance of such factors is found from results of structured interviews with wives in Kondh-dominated villages in western Orissa. These results are at variance with the hypothesis of Malthus about population growth. Factors that may alter the optimal family size as development proceeds are discussed. It is found in our sampling that, on the whole, there is a preference for daughters rather than sons although this is not as strong in the Kondh-dominated villages as in poor villages in the Santal tribal belt of West Bengal. While in the Kondh-dominated villages some discrimination in access to education in favour of boys compared to girls is present, little such or no such discrimination occurs in relation to access to food and medical attention. In the villages surveyed in the West Bengal Santal tribal belt, discrimination in favour of boys is more pronounced than in the Kondh-dominated area in Orissa. While economic considerations help to explain gender discrimination between boys and girls, we find that social and cultural factors also play a major role. Parents in a similar economic situation seem to display substantially different patterns of gender discrimination between children depending on their social and cultural content. It seems that the extent to which economic theories of the family explain family preferences and behaviour depend significantly on the social and cultural context in which they are to be applied.

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The formation of salivary glands entails the proliferation of epithelial cells from the stomatodeum into the underlying ectomesenchyme, culminating in a complex network of ducts and acinar bulbs. The extent to which mucins regulate this process is unknown, but they appear to mediate luminal space formation and maturation. Our aim was to examine mucin expression patterns during the morphogenesis of human salivary glands. Mucin expression - MUC1, 2, 3, 4, 5AC, 5B, 6, and 16 - was analyzed in specimens of developing human salivary glands, obtained from fetuses at 4-24 weeks` gestation, and fully developed salivary glands by immunohistochemistry. Expression patterns were analyzed qualitatively according to the development stage of the salivary glands. Mucins 1, 3, 4, 5B, and 16 were expressed during salivary gland development - being stronger in all ductal segments by the final phases of branching morphogenesis and in mature glands. Acinar cells were negative for most mucins, including MUC1 in mature salivary glands. Mucins 2, 5AC, and 6 were not expressed. Mucins MUC1, 3, 4, 5B, and 16 are expressed in developing human salivary glands and in mature glands, suggesting important roles in the maturation and maintenance of the ductal network.

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The aim of this study was to evaluate the development of the osteoblastic phenotype in human alveolar bone-derived cells grown on collagen type I-coated titanium (Ti) surface (Col-Ti) obtained by plasma deposition acrylic acid grafting compared with machined Ti (M-Ti). Osteoblastic cells were cultured until subconfluence and subcultured on Col-Ti and M-Ti for periods of up to 21 days. Cultures grown on Col-Ti and M-Ti exhibited similar cell morphology. Cell adhesion, total protein content, and alkaline phosphatase (ALP) activity were not affected by Ti surface modification in all evaluated periods. Growth analyses indicated that there were significantly more cells in cultures grown on Col-Ti at day 3. Runt-related transcription factor 2 (Runx2), osteopontin (OPN), and osteoprotegerin (OPG) mRNA expression of cells subcultured on Col-Ti was higher, whereas collagen type I (COL) was lower compared with M-Ti. Ti surface modification neither affected the osteocalcin (OC), ALP and receptor activator of NF-kappa B ligand (RANKL) mRNA expression nor the calcium content extracted from mineralized matrix. These results demonstrated that Col-Ti favours cell growth during the proliferative phase (day 3) and osteoblastic differentiation, as demonstrated by changes in mRNA expression profile during the matrix mineralization phase (day 14), suggesting that this Ti surface modification may affect the processes of bone healing and remodelling. To cite this article:Assis AF, Beloti MM, Crippa GE, de Oliveira PT, Morra M, Rosa AL. Development of the osteoblastic phenotype in human alveolar bone-derived cells grown on a collagen type I-coated titanium surface.Clin. Oral Impl. Res. 20, 2009; 240-246.doi: 10.1111/j.1600-0501.2008.01641.x.

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Strategies to promote bone repair have included exposure of cells to growth factor (GF) preparations from blood that generally include proteins as part of a complex mixture. This study aimed to evaluate the effects of such a mixture on different parameters of the development of the osteogenic phenotype in vitro. Osteoblastic cells were obtained by enzymatic digestion of human alveolar bone and cultured under standard osteogenic conditions until subconfluence. They were subcultured on Thermanox coverslips up to 14 days. Treated cultures were exposed during the first 7 days to osteogenic medium supplemented with a GFs + proteins mixture containing the major components found in platelet extracts [plate I et-derived growth factor-BB, transforming growth factor (TGF)-beta 1, TGF-beta 2, albumin, fibronectin, and thrombospondin] and to osteogenic medium alone thereafter. Control cultures were exposed only to the osteogenic medium. Treated cultures exhibited a significantly higher number of adherent cells from day 4 onward and of cycling cells at days 1 and 4, weak alkaline phosphatase (ALP) labeling, and significantly decreased levels of ALP activity and mRNA expression. At day 14, no Alizarin red-stained nodular areas were detected in cultures treated with GFs + proteins. Results were confirmed in the rat calvaria-derived osteogenic cell culture model. The addition of bone morphogenetic protein 7 or growth and differentiation factor 5 to treated cultures upregulated Runx2 and ALP mRNA expression, but surprisingly, ALP activity was not restored. These results showed that a mixture of GFs + proteins affects the development of the osteogenic phenotype both in human and rat cultures, leading to an increase in the number of cells, but expressed a less differentiated state.

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Frizzled genes encode a family of Wnt ligand receptors, which have a conserved cysteine-rich Wnt binding domain and include both transmembrane and secreted forms. Work by others has shown that experimental perturbation of Wnt signaling results in aberrant hair formation, hair growth, and hair structure. To date, however, there is no information on the contribution of individual Frizzled proteins to hair development. We now report that Frizzled-3 expression in skin is restricted to the epidermis and to the developing hair follicle. Northern analysis on total mouse skin mRNA revealed a single Frizzled-3 transcript of 3.7 kb. Reverse transcription-polymerase chain reaction and in situ hybridization analysis revealed Frizzled-3 expression in epidermal and hair follicle keratinocytes. Frizzled-3 transcripts are first detected in discrete foci in the developing epidermis of 13 d embryos and later in the hair follicle placodes of 15 d embryos, suggesting a role for this Frizzled isoform in follicle development. In 17 d embryos and id old newborn mice Frizzled-3 expression is limited to suprabasal keratinocytes and is not seen in pelage follicles until 3 d postpartum. In 7 d old neonatal skin, Frizzled-3 is expressed throughout the epidermis and in the outer cell layers of hair follicles. We have also identified the mRNA encoding human Frizzled-3 in epidermal keratinocytes and in the HaCaT keratinocyte cell line. Human Frizzled-3 mRNA encodes a 666 amino acid protein with 97.8% identity to the mouse protein. The human Frizzled-3 gene was mapped using a radiation-hybrid cell line panel to the short arm of chromosome 8 between the markers WI-1172 and WI-8496 near the loci for the Hypotrichosis of Marie Unna and Hairless genes.

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The plasma membrane Ca2+ pump is a key regulator of cytosolic free Ca2+. Recent studies have demonstrated the dynamic expression of the plasma membrane Ca2+ pump in a variety of cell types. Furthermore, alterations in plasma membrane calcium pump activity have now been implicated in human disease. In this study, the development of a technique to quantitatively assess mRNA expression of the human plasma membrane Ca2+ ATPase (PMCA1) isoform of the plasma membrane Ca2+ pump, using a real-time reverse transcriptase-polymerase chain reaction (real-time RT-PCR) assay in a human breast epithelial cell line (MCF-7) is described. The sequences of the PMCA1 primers and probe for real-time RT-PCR are presented. The results also indicate that PMCA1 mRNA can be normalized to both 18S ribosomal RNA (18S rRNA) and human glyceraldehyde-3-phosphate dehydrogenase (hGAPDH) in MCF-7 cells. Real-time RT-PCR will be most useful in assessing PMCA1 mRNA expression in cases where only low amounts of RNA are available and/or when numerous samples must be assessed simultaneously. (C) 2001 Elsevier Science Inc. All rights reserved.