968 resultados para Holstein-friesian Cows
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Wentzke: 1. Rede, in der ersten preußischen Kammer in der Adreßdebatte am 8. Januar 1851 nicht gehalten: Scharfe Kritik der Politik des Novemberministeriums in der deutschen Frage; Aufzählung seiner Niederlagen. - 2. Rede, ebenda in der Schleswig-Holsteinischen Frage am 15. Februar gehalten: Angriff auf die Politik des Ministeriums
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Boberach: Die Statistiken und ihre Kommentierung sollen den Abgeordneten bei ihrer Entscheidung über Zolleinheit und -tarife helfen
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Boberach: Für den Verfassungsstreit wird darauf hingewiesen, daß unter Beteiligung der Landstände gültige Reformen durchgeführt wurden wie Ablösung bäuerlicher Lasten, Gewerbesteuerermäßigung, Koalitionsfreiheit, Öffentlich- und Mündlichkeit der Strafrechtspflege mit Schwurgerichten, Aufhebung der Polizeigerichtsbarkeit, Mitwirkung der Landstände bei Ernennung von Oberrichtern
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Boberach: Ein Artillerieoffizier erhebt den Vorwurf, daß es in den Elbherzogtümern für die Soldaten und besonders die Offiziere der Karriere dienlich war, Preuße zu sein, und warnt die Schleswig-Holsteiner vor ihren preußischen "Freunden"; sie sollen den preußischen Einfluß in Schleswig-Holstein beseitigen
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Boberach: Auf eine ausführliche historische Schilderung der Rechtsverhältnisse von Schleswig und Holstein folgt die Darstellung der Ereignisse in den Elbherzogtümern bis zum 12. April 1848
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Boberach: Die Ereignisse werden unter dem Gesichtspunkt dargestellt, daß der Grundsatz der Volkssouveränität die Deutschen in Schleswig-Holstein berechtigt, die dänische Herrschaft abzulehnen und die Versuche der Dänisierung Ursache des Krieges waren
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Cholesterol deficiency, a new autosomal recessive inherited genetic defect in Holstein cattle, has been recently reported to have an influence on the rearing success of calves. The affected animals show unresponsive diarrhea accompanied by hypocholesterolemia and usually die within the first weeks or months of life. Here, we show that whole genome sequencing combined with the knowledge about the pedigree and inbreeding status of a livestock population facilitates the identification of the causative mutation. We resequenced the entire genomes of an affected calf and a healthy partially inbred male carrying one copy of the critical 2.24-Mb chromosome 11 segment in its ancestral state and one copy of the same segment with the cholesterol deficiency mutation. We detected a single structural variant, homozygous in the affected case and heterozygous in the non-affected carrier male. The genetic makeup of this key animal provides extremely strong support for the causality of this mutation. The mutation represents a 1.3kb insertion of a transposable LTR element (ERV2-1) in the coding sequence of the APOB gene, which leads to truncated transcripts and aberrant splicing. This finding was further supported by RNA sequencing of the liver transcriptome of an affected calf. The encoded apolipoprotein B is an essential apolipoprotein on chylomicrons and low-density lipoproteins, and therefore, the mutation represents a loss of function mutation similar to autosomal recessive inherited familial hypobetalipoproteinemia-1 (FHBL1) in humans. Our findings provide a direct gene test to improve selection against this deleterious mutation in Holstein cattle.
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The goal of this study was to investigate the transmissibility of border disease (BD) virus to seronegative cows via artificial insemination with cryopreserved semen from a bull persistently infected with BD virus. Five pestivirus naive cows were inseminated with BD virus-infected semen. Blood was collected for detection of pestivirus antibody by means of an ELISA on day 0 (day of insemination) and then every 7 days until day 56, at which time a serum neutralisation test (SNT) for differentiation of BD and BVD virus was carried out. Seroconversion was first noticed in two cows on day 14, in two cows on day 21 and in one cow on day 28. In the SNT, all cows had distinctly positive titres against BD virus. Therefore, BD virus is readily transmitted by infected semen, but none of the cows conceived, most likely because of poor semen quality.
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Eringer cows are often slaughtered due to fertility problems which result from inflammatory and degenerative changes of the uterus or hormonal imbalances. Twenty-one genital tracts from Eringer cows suffering from fertility problems were collected in the abattoir. The purpose of the study was the macroscopic evaluation of the ovaries and the uterus followed by a histological and microbiological analysis of the uterus. Data from inseminations and calvings were provided by the Eringer breeding association and through the internet portal www.agate.ch. Median age of the cows was 6.9 years, number of calves per cow was 2.5 and median period between last calving and slaughter was 1.5 years. In 13 from 21 of the urogenital tracts examined, macroscopic abnormalities of the ovaries and/or histologic or microbiologic findings in the uterus could explain fertility-associated slaughter.
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The response of cholesterol metabolism to a negative energy balance (NEB) induced by feed restriction for 3 weeks starting at 100 days in milk (DIM) compared to the physiologically occurring NEB in week 1 postpartum (p.p.) was investigated in 50 dairy cows (25 control (CON) and 25 feed-restricted (RES)). Blood samples, liver biopsies and milk samples were taken in week 1 p.p., and in weeks 0 and 3 of feed restriction. Plasma concentrations of total cholesterol (C), phospholipids (PL), triglycerides (TAG), very low density lipoprotein-cholesterol (VLDL-C) and low density lipoprotein-cholesterol (LDL-C) increased in RES cows from week 0 to 3 during feed restriction and were higher in week 3 compared to CON cows. In contrast, during the physiologically occurring NEB in week 1 p.p., C, PL, TAG and lipoprotein concentrations were at a minimum. Plasma phospholipid transfer protein (PLTP) and lecithin:cholesterol acyltransferase (LCAT) activities did not differ between week 0 and 3 for both groups, whereas during NEB in week 1 p.p. PLTP activity was increased and LCAT activity was decreased. Milk C concentration was not affected by feed restriction in both groups, whereas milk C mass was decreased in week 3 for RES cows. In comparison, C concentration and mass in milk were elevated in week 1 p.p. Hepatic mRNA abundance of sterol regulatory element-binding factor-2 (SREBF-2), 3-hydroxy-3-methylglutaryl-coenzyme A synthase 1 (HMGCS1), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), and ATP-binding cassette transporter (ABCA1) were similar in CON and RES cows during feed restriction, but were upregulated during NEB in week 1 p.p. compared to the non-lactating stage without a NEB. In conclusion, cholesterol metabolism in dairy cows is affected by nutrient and energy deficiency depending on the stage of lactation.
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Welsch (Projektbearbeiter): Frisch-fröhliches Gedicht anläßlich der Niederschlagung der badischen revolutionären Aufstände vom April und September 1848 mit Hilfe von Bundestruppen des VIII. Armeekorps (württembergisches, hessisches und nassauisches Militär)
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Welsch (Projektbearbeiter): Siegesgedicht anläßlich der Beschießung des am 5. April 1849 in der Bucht von Eckernförde erschienenen dänischen Geschwaders durch deutsche Strandbatterien, wobei das Linienschiff 'Christian VIII.' in Brand geriet und aufgegeben werden mußte und die Fregatte 'Gefion' zur Übergabe gezwungen wurde
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Welsch (Projektbearbeiter): Darlegung des deutschen Standpunkts in der Schleswig-Holstein-Frage. Hintergrund: Konstituierung einer provisorischen Regierung für Schleswig-Holstein in Rendsburg (24. März 1848)
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In Fraktur