Can a targeted psychological intervention be effective for young people following a first manic episode? Results from an 18-month pilot study.

Aim: There is a scarce literature describing psychological interventions for a young, first-episode cohort who have experienced psychotic mania. This study aimed to assess whether a manualized psychological intervention could be effective in reducing symptomatology and relapse, and improve functional outcome in this population. Methods: The study was an open-label design, drawn from a larger pharmacotherapy trial. All participants in the pharmacotherapy trial were offered a manualized psychological intervention in addition to case management. Inclusion in the psychotherapy group was based on participant's choice, and on completion of four or more of the eight modules offered. All clinical files were audited to ensure accuracy of group allocation. Forty young people aged 15 to 25 years old who had experienced a manic episode with psychotic features were recruited into the study, with 20 people in the combined treatment as usual plus psychotherapy group (P+TAU), and an equal number of matched control participants who received treatment as usual (TAU) within the same service. All participants were prescribed antipsychotic and mood-stabilizing medication. Symptomatic, functional and relapse measures were taken both at baseline and at 18-month follow-up. Results: Manic symptoms improved significantly for both groups, with no differences between groups. Depression scores and overall symptom severity were significantly lower in the P + TAU group. No differences were evident between groups with regard to numbers or type of relapse. The P + TAU group had significantly better social and occupational functioning after 18 months. Conclusion: This study suggests that a manualized psychological intervention targeted to a first-episode population can be effective in reducing depression and overall symptom severity, and can improve functional outcome following a first episode of psychotic mania.

Informe preliminar del Crucero Unuane 6711. 18 noviembre - 20 diciembre. Primavera 1967

Informe del crucero de primavera 6711 a bordo del Unanue, que formó parte del programa de cruceros del Instituto del Mar del Perú para 1967. El mar fue explorado de Cabo Blanco a Ilo, mediante 19 perfiles perpendiculares a la costa que incluyeron 137 estaciones de observación, con un recorrido de 4870 millas.

Situación del recurso merluza y sus características biológicas en la primavera de 1978 crucero 7811-II TAREQ II (18 de octubre - 8 de noviembre 1978)

Evalúa el stock de la merluza y de otros recursos dermesales, determina la intensidad del desove y la distribución del stock reproductivo, así como las condiciones ambientales que están influyendo en la distribución y concentración del recurso.

18/4/20, [football] association, Stade Bergeyre, équipe Olympique : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58919

18/4/20, [football] association, Stade Bergeyre, équipe Olympique : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58920

[Avenue du Palais à] St Cloud, concours de patinettes à moteur, 18/4/20 : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58921

[Avenue du Palais à] St Cloud, 18/4/20, concours de patinettes à moteur : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58922

18/6/20, train chauffé au mazout [i. e. locomotive roulant au mazout et circulant entre la gare d'Austerlitz et Tours pour une démonstration] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59734

18/6/20, train chauffé au mazout [i. e. locomotive roulant au mazout et circulant entre la gare d'Austerlitz et Tours pour une démonstration], M. Le Trocquer [ministre des travaux publics] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59737

18/6/20, train chauffé au mazout [i. e. locomotive roulant au mazout et circulant entre la gare d'Austerlitz et Tours pour une démonstration] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59739