Avaliação de concentração de citocinas no soro de pacientes portadoras de lesão intraepitelial escamosa de baixo grau, lesão intraepitelial escamosa de alto grau e carcinoma cervical invasor

A infecção genital por Papilomavírus Humano (HPV) é uma das doenças sexualmente transmissíveis (DST), de origem viral, mais prevalente no mundo. As lesões intraepiteliais escamosas de baixo grau (LIEBG) e de alto grau (LIEAG), assim como carcinoma cervical invasor (CCI), estão associadas à presença do HPV. A resposta imune tem papel importante na infecção pelo HPV na cérvice uterina, sendo as citocinas importantes reguladoras da transcrição viral. Avaliar a concentração de IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IFN-γ e TNF-α no soro de mulheres portadoras de LIEBG, LIEAG e CCI. Foram incluídas no estudo 40 mulheres com diagnóstico histopatológico de LIEBG (n=11), LIEAG (n=10), CCI (n=10) e 9 mulheres com suspeita de doença HPV induzida, mas sem alterações histopatológicas na biópsia do colo do útero (controle), atendidas no Ambulatório de Colposcopia da Faculdade de Medicina de Botucatu (UNESP) e no Ambulatório de Ginecologia Preventiva do Hospital Amaral Carvalho, Jaú, SP. O sangue periférico foi colhido por punção venosa e o soro armazenado até o processamento. A dosagem das citocinas no soro foi avaliada por ensaio imunoenzimático (ELISA). A pesquisa de HPV foi realizada empregando-se a técnica da reação em cadeia da polimerase (PCR). Os dados sócio-demográficos foram obtidos por entrevista no momento da consulta ginecológica. A mediana de idade das pacientes do grupo controle, LIEBG, LIEAG, e CCI foi de 38 (21-69), 32,5 (17-51), 39 (23-65) e 51,5 (29-72), respectivamente. Houve diferença estatisticamente significante de mediana de idade das pacientes do grupo CCI quando esta foi comparada com os demais grupos. Em relação às características das pacientes, 76% eram brancas, 68% relataram união estável, 31% concluíram o 2º grau, 42% eram fumantes, 37% das mulheres relataram 3 ou mais parceiros sexuais durante... (Resumo completo, clicar acesso eletrônico abaixo)

Distribuição de renda e pobreza no Brasil rural

Since the 60's, the population censuses have revealed a high degree of social inequality in Brazil. The concentration of income, as measured by the Gini index, showed persistently high since then. After the year 2001, we note that the trajectory stability is disrupted and the Gini index begins to show a downward trend. In relation to poverty, there has been two periods in recent history in which there was consistent decrease in the proportion of poor in the years immediately after the Real Plan in 2003 and in the year 2003 onwards. This research aimed to analyze poverty and income distribution in rural Brazil. In this crop sector, it is noted that the average perceived by the rural population is below the Brazilian income and, therefore, there is an increase in the number of poor. In addition, income in rural areas is less concentrated compared to the urban environment. Finally, as occurred in Brazil, there is a rural improvement in indicators of poverty and inequality in the last 10 years. Finally, this paper analyzes the changes that may have contributed to the fall in inequality and rural poverty, including the policy of rural settlement, the credit program to the family farmer (PRONAF) and rural retirement

Impacto da saúde bucal na qualidade de vida de adolescentes grávidas

Pós-graduação em Odontologia Preventiva e Social - FOA

Vivendo nos interstícios do Cerrado: encurralados entre o agronegócio e Unidades de Conservação

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Condição periodontal, perda dentária e diferenças socioeconômicas em adultos e idosos brasileiros

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Sobrecarga w sofrimento psíquico em familiares de portadores de transtorno de pânico com agorafobia

Pós-graduação em Saúde Coletiva - FMB

Fundo Nacional do Idoso e as políticas de gestão do envelhecimento da população brasileira

Demographic census from the last decades of the twentieth century began to reveal a tendency concerning the increasing average age of the population. The Brazilian government began introducing ways to manage the effects and consequences of this trend, the most recent being the creation of the "Fundos do Idoso" (Funds for seniors) in the Federal, state and municipal spheres. That law allows transferring federal taxes from common citizens and companies to the funds. This article is specifically written as a critical examination of this governmental initiative towards the problem of an ageing population from the point of view as to how the law has been implemented. With the creation of the funds there will be the enlargement and improvement of services destined for seniors. However, the law mentioned above does not predict an active participation of the seniors in the management of this funds and policies that will come as result.

Hipomineralização molar-incisivo em escolares da rede municipalde ensino da área urbana e rural de Manaus-AM

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Factors associated with sarcopenia in subjects aged 80 years and over

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Association between sleep quality and quality of life in nursing professionals working rotating shifts

Objective: To analyze the association between sleep quality and quality of life of nursing professionals according to their work schedules. Methods: A prospective, cross-sectional, observational study was conducted between January and December 2010, with 264 nursing professionals, drawn from 989 subjects at Botucatu General Hospital and stratified by professional category. The Pittsburg Sleep Quality Index and the WHOQOL-bref were administered to evaluate sleep quality and quality of life, respectively. Self-reported demographic data were collected with a standard form. Continuous variables were reported as means and standard deviations, and categorical variables were expressed as proportions. Associations were evaluated using Spearman's correlation coefficient. The association of night-shift work and gender with sleep disturbance was evaluated by logistic regression analysis using a model adjusted for age and considering sleep disturbance the dependent variable. The level of significance was p < 0.05. Results: Night-shift work was associated with severe worsening of at least one component of sleep quality in the model adjusted for age (OR = 1.91; 95% CI 1.04; 3.50; p = 0.036). Female gender was associated with sleep disturbance (OR = 3.40; 95% CI 1.37; 8.40; p = 0.008). Quality of life and quality of sleep were closely correlated (R = -0.56; p < 0.001). Conclusions: Characteristics of the nursing profession affect sleep quality and quality of life, and these two variables are associated.

Avaliação comparativa da ancestralidade em mulheres com melasma facial: um estudo transversal

Pós-graduação em Patologia - FMB

Condições de trabalho e transtornos mentais comuns em professores da rede básica municipal de encino de Bauru-SP

Pós-graduação em Saúde Coletiva - FMB

Influência dos polimorfismos Taql e Bsml do gene do receptor de vitamina D no surgimento de infecção, tempo de internação e mortalidade em pacientes queimados

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Onde a luta se travar: a expansão das Assembleias de Deus no Brasil urbano (1946-1980)

Pós-graduação em História - FCLAS

O papel da Universidade Aberta à Terceira Idade na educação ambiental

Population aging and environmental protection have gained special importance after the economic, demographic and social recent changes. The objective of this paper was to promote theoretical and reflective review with emphasis on convergence between sustainable development and educational activities promoted by the University of the Third Age. We conducted a literature review to give full articles from the descriptors: aged, sustainable development indicators and environmental protection, published in English, Spanish and Portuguese, between January 1994 and June 2014, in national and international journals on the basis LiIlacs, Bireme and Medline. We used systematic data collection for sample analysis. The results indicate that the University of the Third Age develops teaching, research and extension, through actions based on aging and educational assumptions. In this context, environmental education is presented as a pedagogical process capable of awakening the critical capacity of the elderly, making it active social worker and leading him to a cultural design which ensures establishment of sustainable harmonious relationship with nature. It was concluded that the University of the Third Age contributes to initiatives that emphasize the relationships between systems and economic processes or social and natural processes, generating the construction of social values, knowledge, skills, attitudes and skills aimed at the conservation of the environment.