Easily handling penicillin G acylase magnetic cross-linked enzymes aggregates: Catalytic and morphological studies

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Numerical and experimental investigations of three-dimensional container filling with Newtonian viscous fluids

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Concepção morfológica de fórceps, para intervenção no paciente em posição supina e o operador sentado

Ergonomics, the science of working rationalization, seeks the best relationship between man and his working tools. In Dentistry, ergonomics is present as for the professional working correctly seated, in functional comfort, intervening of supine position patient, by means of suitable equipment and instrument. Nowadays, dental equipment is justly rationalized; however, some instruments should take shape, in order to adapt those requirements. The hand tool design should permit a comfortable, non-slip and safe handling. Thus, anatomical details, the correct position of the operator for its use and specific characteristics of application should be taken into account. The instrument under analysis - forceps - was conceived according to these requirements along with a new alveolar tooth extraction technique, based on electromyographic and biomechanical studies. The morphology of the instrument, which makes possible a simple and natural kinetics of the operator, was obtained by changing the paradigm of the conventional cross-action instruments (whose grip is always on the arms of the tool), divesting the handle from the tool arm. This induced on anatomical conceiving of perpendicular handles to the extremity of the tool arm, resulting an efficient and effective instrument, according to indicated on its experimental phase

Opinião de profissionais da educação e da saúde sobre o uso da prancha ortostática para o aluno com paralisia cerebral

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The effects of the C-terminal amidation of mastoparans on their biological actions and interactions with membrane-mimetic systems

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Long-term obesity promotes alterations in diastolic function induced by reduction of phospholamban phosphorylation at serine-16 without affecting calcium handling

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

BILL E. KUNKLE INTERDISCIPLINARY BEEF SYMPOSIUM: Temperament and acclimation to human handling influence growth, health, and reproductive responses in Bos taurus and Bos indicus cattle

Temperament in cattle is defined as the fear-related behavioral responses when exposed to human handling. Our group evaluates cattle temperament using 1) chute score on a 1 to 5 scale that increases according to excitable behavior during restraint in a squeeze chute, 2) exit velocity (speed of an animal exiting the squeeze chute), 3) exit score (dividing cattle according to exit velocity into quintiles using a 1 to 5 scale where 1 = cattle in the slowest quintile and 5 = cattle in the fastest quintile), and 4) temperament score (average of chute and exit scores). Subsequently, cattle are assigned a temperament type of adequate temperament (ADQ; temperament score <= 3) or excitable temperament (EXC; temperament score > 3). To assess the impacts of temperament on various beef production systems, our group associated these evaluation criteria with productive, reproductive, and health characteristics of Bos taurus and Bos indicus-influenced cattle. As expected, EXC cattle had greater plasma cortisol vs. ADQ cattle during handling, independent of breed type (B. indicus x B. taurus, P < 0.01; B. taurus, P < 0.01; B. indicus, P = 0.04) or age (cows, P < 0.01; heifers or steers, P < 0.01). In regards to reproduction, EXC females had reduced annual pregnancy rates vs. ADQ cohorts across breed types (B. taurus, P = 0.03; B. indicus, P = 0.05). Moreover, B. taurus EXC cows also had decreased calving rate (P = 0.04), weaning rate (P = 0.09), and kilograms of calf weaned/cow exposed to breeding (P = 0.08) vs. ADQ cohorts. In regards to feedlot cattle, B. indicus EXC steers had reduced ADG (P = 0.02) and G:F (P = 0.03) during a 109-d finishing period compared with ADQ cohorts. Bos taurus EXC cattle had reduced weaning BW (P = 0.04), greater acute-phase protein response on feedlot entry (P <= 0.05), impaired feedlot receiving ADG (P = 0.05), and reduced carcass weight (P = 0.07) vs. ADQ cohorts. Acclimating B. indicus x B. taurus or B. taurus heifers to human handling improved temperament (P <= 0.02), reduced plasma cortisol (P < 0.01), and hastened puberty attainment (P <= 0.02). However, no benefits were observed when mature cows or feeder cattle were acclimated to human handling. In conclusion, temperament impacts productive, reproductive, and health characteristics of beef cattle independent of breed type. Hence, strategies to improve herd temperament are imperative for optimal production efficiency of beef operations based on B. taurus and B. indicus-influenced cattle.

Diagnóstico geoambiental e avaliação de risco à saúde humana em terminal de abastecimento no município de Sumaré - SP

The present work deals with the study on the evaluation of the human health risks caused by the leaching of hydrocarbon products from a gas station in Sumaré-SP. First, a geoenvironmental diagnosis had to be done, where information such as: history of the area, chemicals involved, geological characteristics, transport, chemical analysis, were used to make it. The geoenvironmental diagnosis was used in the software RBCA tier 2 which established the risks by all possible pathways. The results indicated that there are risks for groundwater ingestion for commercial (on site and off site) and residential receptors and 10 that there´s risk for inhalation of vapors in enclosed space for the commercial receptor on site. The evaluation also calculated the specific target levels that the area needs to show, in order not to harm human beings and the environment. That makes RBCA a great tool that can helps the remediation actions needed to be done so that the human being and the environment remain secure.

Parametrização de modelo para simulação de distribuição de combustíveis em um terminal

A great competition between companies happens nowadays, due to, among other factors, the globalized economic system, the growing consumer demand and the technological advances. This fact implies the need for fast and efficient tools in decision making. A validated simulation model is able to perform this task. Thus, it was parameterized a simulation model of a fuel distribution terminal. It is a complex system because of its great variability. The model´s data input were collected, however the model was not statistically validated, in other word, does not adequately represent the real system. A search was made for the possible causes of this fact: dividing the compartments of tanker trucks, data collection may have been insufficient, inefficient model for unloading of biofuels