A history of the Jews in England : with portraits and maps

by Albert M. Hyamson

Natural history of surgically treated high-risk prostate cancer

BACKGROUND No data exist on the patterns of biochemical recurrence (BCR) and their effect on survival in patients with high-risk prostate cancer (PCa) treated with surgery. The aim of our investigation was to evaluate the natural history of PCa in patients treated with radical prostatectomy (RP) alone. MATERIALS AND METHODS Overall, 2,065 patients with high-risk PCa treated with RP at 7 tertiary referral centers between 1991 and 2011 were identified. First, we calculated the probability of experiencing BCR after surgery. Particularly, we relied on conditional survival estimates for BCR after RP. Competing-risks regression analyses were then used to evaluate the effect of time to BCR on the risk of cancer-specific mortality (CSM). RESULTS Median follow-up was 70 months. Overall, the 5-year BCR-free survival rate was 55.2%. Given the BCR-free survivorship at 1, 2, 3, 4, and 5 years, the BCR-free survival rates improved by+7.6%,+4.1%,+4.8%,+3.2%, and+3.7%, respectively. Overall, the 10-year CSM rate was 14.8%. When patients were stratified according to time to BCR, patients experiencing BCR within 36 months from surgery had higher 10-year CSM rates compared with those experiencing late BCR (19.1% vs. 4.4%; P<0.001). At multivariate analyses, time to BCR represented an independent predictor of CSM (P<0.001). CONCLUSIONS Increasing time from surgery is associated with a reduction of the risk of subsequent BCR. Additionally, time to BCR represents a predictor of CSM in these patients. These results might help provide clinicians with better follow-up strategies and more aggressive treatments for early BCR.

An inquiry into the sources of the history of the Jews in Spain

by Joseph Jacobs

The return of the Jews to England : being a chapter in the history of English law

by H.S.Q. Henriques

A short history of the Jews in England

by H. P. Stoke

A history of the Jews in England

by Albert M. Hyamson

The history of the Jews of Spain and Portugal : from the earliest times to their final expulsion ... ; with complete translations of all the laws ...

E. H. Lindo

Sephardim : or the history of the Jews in Spain and Portugal

by James Finn

The history of the Jews in China

by S.M. Perlmann

History of the Jews in America : from the period of the discovery of the new world to the present time

by Peter Wiernik

History of amulets, charms and talismans : a historical investigation into their nature and origin

by Michael L. Rodkinson

The history of the Jews in Great Britain : in 3 vol.

by Moses Margoliouth

Prospectus of the Library of Ephraim Deinard at New Orleans, Louisiana : also a list of Jewish antiquities, depicting the "history of religion", on exhibition at the Smithsonian Institution at Washington, D. C., and at New Orleans, Louisiana

Devir Efrayim