Desenvolvimento e estabilidade de formulações semi-solidas contendo extratos de soja (Glycine max (L) Merr.)

Alguns vegetais, como a soja (Glycine max L. Merr), despertam interesse, pois fornecem, entre outras substâncias, as isoflavonas, que apresentam importantes propriedades estrogênicas e, também, atuam como antioxidantes, antifúngicos e anticancerígenos. A menopausa, causada pela deficiência hormonal, é acompanhada de vários transtornos metabólicos, como perda de massa óssea, fenômenos vasomotores, dislipidemia, resistência insulínica, ganho de peso, depressão e aceleração do envelhecimento cutâneo. A terapia de reposição hormonal (TRH) é eficaz, embora possa causar efeitos secundários, como câncer de mama. Nestes casos, a fitoterapia com fitormônios por via cutânea é uma alternativa importante. Dentre as preparações de uso tópico, sistemas emulsionados e géis são muito utilizados, pois favorecem a solubilidade e a estabilidade de fármacos. Para avaliar a estabilidade das formulações, foram consideradas as características organolépticas (aspecto, cor, odor) e as características físico-químicas (valor de pH, viscosidade e densidade, etc.), separação de fases e/ou coalescência. Algumas formulações apresentam-se com características desejáveis e adequadas para a veiculação de isoflavonas presentes em extrato de soja, podendo-se sugeri-las como sistemas adequados e estáveis para sua veiculação pela via dérmica

Algoritmo de resolução de EDO de primeira ordem com implementação em HTML

This work presents a theoretical study of ordinary differential equations of first order directed so as to provide basis for the development of an educational software that helps students and researchers confronted with this issue. The algorithm was developed in HTML language in to that the results provide a website that allows the audience to access the software anywhere which has internet connection

Implementação do algoritmo de Newman para identificação de comunidades em placas gráficas

Communities are present on physical, chemical and biological systems and their identification is fundamental for the comprehension of the behavior of these systems. Recently, available data related to complex networks have grown exponentially, demanding more computational power. The Graphical Processing Unit (GPU) is a cost effective alternative suitable for this purpose. We investigate the convenience of this for network science by proposing a GPU based implementation of Newman community detection algorithm. We showed that the processing time of matrix multiplications of GPUs grow slower than CPUs in relation to the matrix size. It was proven, thus, that GPU processing power is a viable solution for community dentification simulation that demand high computational power. Our implementation was tested on an integrated biological network for the bacterium Escherichia coli

Comparação das técnicas semi-quantitativa e quantitativa nas infecções relacionadas a cateter em neonatos e determinação da resistência à oxacilina nos Staphylococcus spp

Study the semi-quantitative and quantitative technique in the diagnosis of catheter-related infections in newborns and to determine oxacillin resistance in Staphylococcus isolated. It was analyzed 353 catheter tips from 273 newborns in the Neonatal Unit of Hospital FMB. To confirm the diagnosis of infection, were analyzed the clinical data of newborns, the presence of at least one positive blood culture and growth of ≥ 1000 CFU/mL on quantitative culture and/or ³15 UFC on semiquantitative culture, with the same microorganism isolation (species and drug sensitivity) in blood culture and no other focus of infection except the catheter. The disk diffusion technique was used to check similarity of strains and resistance to oxacillin. Of the 353 tips analyzed, 39 were included in this study as the inclusion criteria. The semiquantitative culture was positive in 26 (66.7%) catheters and quantitative culture was positive in 24 (61.5%). Of 273 patients, 19 (6.9%) had a diagnosis of catheter-related bloodstream Infection (CR-BSI). Of the 19 episodes of CR-BSI, S. epidermidis was the predominant etiological agent (84.2%). The resistance to the antibiotic methicillin was found in 14 (73.7%) strains of Staphylococcus. The semiquantitative method was more sensitive (79%) compared with the quantitative method (63%). The use of antibiotics may have influenced the sensitivity of the quantitative method as the microorganisms present in the lumen are exposed to higher concentrations of antibiotics administered via the catheter

Aplicação do algoritmo Rough Sets em um Data Warehouse

This Project aims to develop methods for data classification in a Data Warehouse for decision-making purposes. We also have as another goal the reduction of an attribute set in a Data Warehouse, in which a given reduced set is capable of keeping the same properties of the original one. Once we achieve a reduced set, we have a smaller computational cost of processing, we are able to identify non-relevant attributes to certain kinds of situations, and finally we are also able to recognize patterns in the database that will help us to take decisions. In order to achieve these main objectives, it will be implemented the Rough Sets algorithm. We chose PostgreSQL as our data base management system due to its efficiency, consolidation and finally, it’s an open-source system (free distribution)

Avaliação das alterações celulares nos ovócitos de fêmeas semi-ingurgitadas de carrapatos Rhipicephalus sanguineus (Acari: Ixodidae) decorrentes da exposição ao óleo de andiroba

Os carrapatos são considerados um dos mais importantes grupos dentre os artrópodes, por serem vetores de agentes patogênicos, que podem atacar animais, bem como o próprio homem. Dentre as diversas espécies de carrapato destaca-se a do Rhipicephalus sanguineus, pertencente à família Ixodidae e com ampla distribuição em todos os continentes. Atualmente esta espécie é considerada uma praga urbana, de grande importância médico-veterinária, que parasita principalmente o cão doméstico. Os ovários de carrapatos são considerados órgãos vitais para o sucesso biológico deste grupo de animais. Neste sentido, desenvolver pesquisas para se conhecer a ação de produtos naturais com reconhecida ação repelente ou acaricida, sobre o sistema reprodutor feminino de carrapatos, traria importantes informações para um melhor entendimento dos efeitos da ação destes produtos nos ovócitos desses ectoparasitas, contribuindo principalmente para o desenvolvimento de métodos de controle alternativos menos tóxicos para os organismos não-alvo e menos poluentes para o meio ambiente. Dessa forma, o presente estudo analisou as alterações morfofisiológicas causadas por diferentes concentrações do óleo de andiroba no ovário de fêmeas semiingurgitadas de carrapatos R. sanguineus

Uma proposta de resolução para problemas de roteirização de veículos baseada no algoritmo genético

The vehicle routing problem is to nd a better route to meet a set of customers who are geographically dispersed using vehicles that are a central repository to which they return after serving customers. These customers have a demand that must be met. Such problems have a wide practical application among them we can mention: school transport, distribution of newspapers, garbage collection, among others. Because it is a classic problem as NP-hard, these problems have aroused interest in the search for viable methods of resolution. In this paper we use the Genetic Algorithm as a resolution

Busca quântica de dados XML usando algoritmo de Grover

This paper presents a quantum search algorithm implementation with small modifications. The algorithm idea is to be hybrid, capable to run on classical systems and quantum systems. We present the concepts of quantum search and introduced a pseudo-framework able to generate code for classical computers (C++) and quantum computers (QCL). The algorithms were submitted to simulations, which resulted in a comparative study of the operation of Grover’s algorithm on both systems, carrying out searches in a mass of data in XML format files. As a result, we see very similar numbers between classical and quantum systems, this creates an expectation that the search in real quantum computers is much more efficient.

C^l-contact and C^l-right equivalences of real semi-quasihomogeneous C^l-function germs

In this paper we investigate the C ` versions of contact and right equivalences of real semi-quasihomogeneous C ` function germs, 1 ≤ ` ≤ ∞. The C ` -right equivalence implies C ` -contact equivalence for any 1 ≤ ` ≤ ∞ and in this work we show, up to certain conditions, that for semi-quasihomogeneous C ` function germs the converse is also true. As a consequence, we recover some known results about C∞-right and C∞-contact equivalences of C∞ function germs. We note that we are considering semi-quasihomogeneous function germs with no additional hypothesis of isolated singularity at zero.

Algoritmo híbrido neural-imuno aplicado ao diagnóstico de distúrbios de tensão em sistemas de distribuição de energia elétrica

Pós-graduação em Engenharia Elétrica - FEIS

Algoritmo tabu search especializado para o problema de planejamento da expansao de sistemas de transmissão

Pós-graduação em Engenharia Elétrica - FEIS

Restauración onlay usando técnica semi-directa con resina compuesta: reporte de un caso

Posterior teeth restorations have changed the contemporary treatment philosophy influenced by the aesthetic demand of patients, progress of adhesive material science and techniques for preservation and rehabilitation of affected teeth by dental caries and trauma. The development of Onlay restorations with semi-direct technique in endodontically teeth treated aims to preserve the remaining surfaces, to reduce the possibility of fracture and polymerization shrinkage. In addition, better restoration adaptation and marginal seal, resistance to wear and dimensional stability are achieved. This case reports the rehabilitation of an endodontically treated permanent maxillary first molar in a 13 years old- patient who attended the Araraquara School of Dentistry, Brazil, using Miris 2 Composite resin with semi-direct technique and obtaining an aesthetic and functional restoration in a single appointment. The fundaments and clinical guidelines of the procedure are detailed, based on the review of the literature that supports this conservative treatment.

Estudo comparativo da inclinação do plano oclusal de modelos para cirurgia ortognática montados em dois tipos de articuladores semi-ajustáveis

Purpose: The aim of this study was to compare occlusal plane angulation measured in two different types of semi-adjustable articulators with that obtained on the lateral cephalometric radiograph. Materials and Methods: 20 patients due to undergo orthognathic surgery had dental casts mounted in two different types of semi-adjustable articulators through face bow transfer from the position of the maxilla and occlusal recording to the mandible. After mounting, the inclination of the occlusal plane in the articulators was measured and compared with the inclination measured at on both articulators and compared with the inclination measured on the lateral cephalometric radiographs and between the articulators themselves. The results obtained werestatistically analyzed. Results: Mean angulation values for the Bio Art (7.55º) and Kavo (-5.70º) articulators differ by 13.25º, which is statistically significant (p=0.00). When individually compared to the lateral cephalometric radiograph (5.075º), the Bio Art articulator showed more similar angulation values, with a difference of 2.475º, while the Kavo articulator presented a difference of 10.775º. Conclusion: Neither of the models of semi-adjustable articulators accurately reproduced the inclination of the maxillary occlusal plane of patients with dentofacial deformities; the difference between the two articulators tested and the lateral cephalometric radiograph was lower for the Bio Art than for the Kavo articulator.

Orientação semi-automática de uma sequência de pares de imagens frontais por fototriangulação a partir de fotocoordenadas extraídas pelo SIFT

Pós-graduação em Ciências Cartográficas - FCT