Iowa Lottery Action, April 18-29, 2007, vol. 14, no. 7.

Iowa Lottery newsletter for lottery retailers.

Los Angeles avajaispäivänä 30/7 1932

Kirje 30.7.1932

Iowa Lottery VIP Club Connection, Aug. 2007, vol. 7, no. 3

Iowa Lottery newsletter for VIP Club members.

Iowa Lottery VIP Club Connection, Nov. 2007, vol. 7, no. 4

Iowa Lottery newsletter for VIP Club members.

Professor Nils Meinander 7.11.1958

Kirje

Rouva Saima Jauhiainen 7/1 1960

Kirje

Hki 3/7 1940.

Kirje 3.7.1940

EPI Update, December 7, 2007

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Rouva Onerva Puurula 2/7 1975

Kirje 2.7.1975

Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects.

PURPOSE: To compare the renal hemodynamic and tubular effects of celecoxib, a selective inhibitor of cyclooxygenase-2 (COX-2) to those of naproxen, a nonselective inhibitor of cyclooxygenases in salt-depleted subjects. METHODS AND SUBJECTS: Forty subjects were randomized into four parallel groups to receive 200 mg celecoxib twice a day, 400 mg celecoxib twice a day, 500 mg naproxen twice a day, or a placebo for 7 days according to a double-blind study design. Blood pressure, renal hemodynamics, and urinary water and electrolyte excretion were measured before and for 3 hours after drug intake on days 1 and 7. RESULTS: Celecoxib had no effect on systemic blood pressure, but short-term transient decreases in renal blood flow and glomerular filtration rate were found with the highest dose of 400 mg on day 1. On the first day, both celecoxib and naproxen decreased urine output (P < .05) and sodium, lithium, and potassium excretion (P < .01). On day 7, similar effects on water and sodium excretion were observed. During repeated administration, a significant sodium retention occurred during the first 3 days. CONCLUSION: In salt-depleted subjects, selective inhibition of COX-2 causes sodium and potassium retention. This suggests that an increased selectivity for COX-2 does not spare the kidney, at least during salt depletion.

Puheenjohtaja Niilo Hämäläinen 6/7 1972

Kirje 6.7.1972