Epidemiological Report on the Treatment of Patients with Gestational Trophoblastic Disease in 10 Brazilian Referral Centers Results After 12 Years Since International FIGO 2000 Consensus

OBJECTIVE: To evaluate treatment of Brazilian patients with gestational trophoblastic disease (GTD).STUDY DESIGN: A retrospective cohort study with analysis of medical reports performed in 10 Brazilian referral centers from January 2000 to December 2011.RESULTS: Of 5,250 patients 3 died (0.06%) at the time of uterine evacuation. Spontaneous remission of GTD (group G1) was observed in 4,103 cases, and 1,144 (21.8%) progressed to gestational trophoblastic neoplasia (GTN) (G2). In G1 2,716 (66.2%) had complete hydatidiform mole (HM) and 1,210, partial HM (29.5%); 3,772 patients (92.7%) recovered as noted in December 2012. In G2, of 1,118 patients treated, initial histopathological results of previous gestation were complete HM (77.5% [n = 886]), partial HM (8.8% [n = 100]), and choriocarcinoma (8.0% [n = 92]); 930 (81.3%) were low-risk, 200 (17.5%) were high-risk GTN, and 14 had placental site trophoblastic tumor (PSTT) (1.2%); cure was achieved in 1,078 cases (96.4%), but 26 patients (2.3%) died (4 low-risk [0.4%], 19 high-risk [9.5%], and 3 PSTT [21.4%]).CONCLUSION: The highest death rates were due to high-risk GTN and PSTT. Patients with molar pregnancy should be referred to a referral center for an early diagnosis and prompt treatment of GTN in order to reduce the morbidity and mortality found in advanced stages.

Forward-backward asymmetry of Drell-Yan lepton pairs in pp collisions at root s=7 TeV

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Measurement of the inelastic proton-proton cross section at root s=7 TeV

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Search for anomalous production of highly boosted Z bosons decaying to mu(+)mu(-) in proton-proton collisions at root s=7 TeV

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Search for a non-standard-model Higgs boson decaying to a pair of new light bosons in four-muon final states

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Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at root s=0.9 and 2.36 TeV

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Search for supersymmetry in events with b jets and missing transverse momentum at the LHC

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Measurement of the inclusive Z cross section via decays to tau pairs in pp collisions at root s=7 TeV

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Search for massive resonances in dijet systems containing jets tagged as W or Z boson decays in pp collisions at root s=8 TeV

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Search for massive resonances decaying into pairs of boosted bosons in semi-leptonic final states at root s=8 TeV

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Search for the associated production of the Higgs boson with a top-quark pair

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Measurement of prompt J/psi pair production in pp collisions at root s = 7 Tev

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Study of hadronic event-shape variables in multijet final states in pp collisions at root s=7 TeV

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Search for neutral MSSM Higgs bosons decaying to a pair of tau leptons in pp collisions

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Measurement of the t(t)over-bar production cross section in the dilepton channel in pp collisions at root s=7 TeV

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