Notes of proceedings and cases determined in the high court of errors and appeals, the court of chancery, and the orphans court of the state of Delaware, 1792-1832

Contains summaries of cases heard by the Delaware Supreme Court and the Delaware Appeals Court in the counties of Sussex, Kent, and Newcastle covering a variety of legal topics. Supposedly based on Wilson's Red Book.

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Naïve FoxP3-expressing regulatory T-cells (Tregs) are essential to control immune responses via continuous replenishment of the activated-Treg pool with thymus-committed suppressor cells. The mechanisms underlying naïve-Treg maintenance throughout life in face of the age-associated thymic involution remain unclear. We found that in adults thymectomized early in infancy the naïve-Treg pool is remarkably well preserved, in contrast to conventional naïve CD4 T-cells. Naïve-Tregs featured high levels of cycling and pro-survival markers, even in healthy individuals, and contrasted with other circulating naïve/memory CD4 T-cell subsets in terms of their strong γc-cytokine-dependent signaling, particularly in response to IL-7. Accordingly, ex-vivo stimulation of naïve-Tregs with IL-7 induced robust cytokine-dependent signaling, Bcl-2 expression, and phosphatidylinositol 3-kinase (PI3K)-dependent proliferation, whilst preserving naïve phenotype and suppressive capacity. Altogether, our data strongly implicate IL-7 in the thymus-independent long-term survival of functional naïve-Tregs, and highlight the potential of targeting the IL-7 pathway to modulate Tregs in different clinical settings.

High daily rate trickling filter performance : under the direction of the Board of State Health Commissioners, Upper Mississippi River Basin Sanitaton Agreement /

Includes bibliographical references.

Preferred list of books for township and high school libraries in the state of Michigan.

Mode of access: Internet.

Annual report of the American High Commissioner at Port au Prince, Haiti, to the Secretary of State.

1929 issued as U. S. Dept. of State Publication no. 76, Latin American series, no. 3.

Family values for democratic living : a home economics course designed for high school seniors by the University of the State of New York, the State Education Department, Bureau of Home Economics, Albany.

Mode of access: Internet.

Annual report of the American High Commissioner at Port au Prince, Haiti, to the Secretary of State.

Vol. for 1922 has title: Report of the American High Commissioner at Port au Prince, Haiti.

Ireland in the seventeenth century; or, The Irish massacres of 1641-2, their causes and results. Illustrated by extracts from the unpublished state papers, the unpublished mss. in the Bodleian library, Lambeth library, and the library of the Royal Dublin society, relating to the plantations of 1610-39; a selection from the unpublished depositions relating to the massacres ... and the reports of the trials in the High court of justice in 1652-4, from the unpublished mss. in Trinity college, Dublin.

Mode of access: Internet.

Report of the Tennessee State high school testing program,

References: p. 92.

Air fluorescence excited by high-altitude nuclear explosions /

"United States Atomic Energy Commission Contract W-7405-Eng. 36"--Cover.

The perpetual care of high-level radioactive liquid wastes in New York State; a Technological and cost study,

This work performed under contract C-16348 for the New York State Office of Atomic Development.