993 resultados para Endotoxin-induced uveitis


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Experiments were conducted to investigate the ultrafine-grained (UFG) microstructures in the surface layer of an aluminum alloy 7075 heavily worked by ultrasonic shot peening. Conventional and high-resolution electron microscopy was performed at various depths of the deformed layer. Results showed that UFG structures were introdued into the surface layer of 62 μm thick. With increasing strain, the various microstructural features, e.g., the dislocation emission source, elongated microbands, dislocation cells, dislocation cell blocks, equiaxed submicro-, and nano-crystal grains etc., were successively produced. The grain subdivision into the subgrains was found to be the main mechanism responsible for grain refinement. The simultaneous evolution of high boundary misorientations was ascribed to the subgrain boundary rotation for accommodating further strains. Formed microstructures were highly nonequilibratory.  2002 Acta Materialia Inc. Published by Elsevier Science Ltd. All rights reserved.

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波浪作用下海床的稳定性分析是海洋工程地质评价的重要内容。海床的稳定性可通过计算分析其随时间变化的有效应力场来评估。建议了一个周期载荷作用下土体的本构模型,并用于计算波浪作用下海床的应力与变形。采用Biot固结理论和有限单元法,分析了海床的动态应力场与孔隙水压力场。波浪作用下两种渗透系数时有效应力的动态变化过程结果对比,反映了渗透消散作用对海床有效应力变化的影响。

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A numerical model is proposed to simulate fracture induced by the coalescence of numerous microcracks, in which the condition for coalescence between two randomly nucleated microcracks is determined in terms of a load-sharing principle. The results of the simulation show that, as the number density of nucleated microcracks increases, stochastic coalescence first occurs followed by a small fluctuation, and finally a newly nucleated microcrack triggers a cascade coalescence of microcracks resulting in catastrophic failure. The fracture profiles exhibit self-affine fractal characteristics with a universal roughness exponent, but the critical damage threshold is sensitive to details of the model. The spatiotemporal distribution of nucleated microcracks in the vicinity of critical failure follows a power-law behaviour, which implies that the microcrack system may evolve to a critical state.

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It is known that the press formability and the elongation of laser textured sheet are improved, and the service life of textured roll is longer than that of the un-textured roll due to hardening of the treated surface. One of the goals to develop high repetitive rate YAG laser-induced discharge texturing (LIDT) is to get deeper hardening zone. By observing and measuring cross-section of LIDT spots in different discharge conditions, it is found that the single-crater, which is formed by the discharge conditions of anode, which is covered by an oil film and with rectangular current waveform, has the most depth of heat affected zone (HAZ) comparing with other crater shapes when discharge energy is the same. The depth of HAZ is mainly depends on pulse duration when the discharge spot is single-crater. The results are analyzed.

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A numerical study on wave dynamic processes occurring in muzzle blast flows, which are created by a supersonic projectile released from the open-end of a shock tube into ambient air, is described in this paper. The Euler equations, assuming axisymmetric flows, are solved by using a dispersion-controlled scheme implemented with moving boundary conditions. Three test cases are simulated for examining friction effects on the muzzle flow. From numerical simulations, the wave dynamic processes, including two blast waves, two jet flows, the bow shock wave and their interactions in the muzzle blasts, are demonstrated and discussed in detail. The study shows that the major wave dynamic processes developing in the muzzle flow remain similar when the friction varies, but some wave processes, such as shock-shock interactions, shock-jet interactions and the contact surface instability, get more intensive, which result in more complex muzzle blast flows.

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A new failure mode is observed in circular brass foils induced by laser beam. The new failure is based on the following experimental facts : (1) the peripheries of the circular brass foils are fixed and the surfaces of the foils are radiated by laser beam ; (2) the laser beam used is considered to be non-Gaussian spatially, actually an approximately uniform distribution limited in a certain size spot ; (3) the pulse on time of laser beam should be 250 μs, i.e. so called long duration pulse laser. The failure process consists of three stages ; i.e. thermal bulging, localized shear deformation and perforation by plugging. The word reverse in reverse bulging and plugging mode means that bulging and plugging occur in the direction of incident laser beam. To study the newly-discovered type of failure quantitatively, analytical solutions for the axisymmetric temperature field and deflection curve are derived. The calculated results show that the newly discovered failure mode is attributed to the spatial structure effect of laser beam indeed.

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In heterogeneous brittle media, the evolution of damage is strongly influenced by the multiscale coupling effect. To better understand this effect, we perform a detailed investigation of the damage evolution, with particular attention focused on the catastrophe transition. We use an adaptive multiscale finite-element model (MFEM) to simulate the damage evolution and the catastrophic failure of heterogeneous brittle media. Both plane stress and plane strain cases are investigated for a heterogeneous medium whose initial shear strength follows the Weibull distribution. Damage is induced through the application of the Coulomb failure criterion to each element, and the element mesh is refined where the failure criterion is met. We found that as damage accumulates, there is a stronger and stronger nonlinear increase in stress and the stress redistribution distance. The coupling of the dynamic stress redistribution and the heterogeneity at different scales result in an inverse cascade of damage cluster size, which represents rapid coalescence of damage at the catastrophe transition.

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Unlike most previous studies on vortex- induced vibrations of a cylinder far from a boundary, this paper focuses On the influences of close proximity of a submarine pipeline to a rigid seabed boundary upon the dynamic responses of the pipeline in ocean currents. The effects of gap-to-diameter ratio and those of the stability parameter on the amplitude and frequency responses of a pipeline are investigated experimentally with a novel hydro-elastic facility. A comparison is made between the present experimental results Of the amplitude and frequency responses for the pipes with seabed boundary effects and those for wall-free cylinders given by Govardhan and Williamson (2000) and Anand ( 1985). The comparison shows that the close proximity of a pipeline to seabed has much influence on the vortex- induced vibrations of the pipeline. Both the width of the lock-in ranges in terms of V, and the dimensionless amplitude ratio A(max)/D become larger with the decrease of the gap-to-diameter ratio e/D. Moreover, the vibration of the pipeline becomes easier to occur and its amplitude response becomes more intensive with the decrease of the stability parameter, while the pipeline frequency responses are affected slightly by the stability parameter.

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In order to study the failure of disordered materials, the ensemble evolution of a nonlinear chain model was examined by using a stochastic slice sampling method. The following results were obtained. (1) Sample-specific behavior, i.e. evolutions are different from sample to sample in some cases under the same macroscopic conditions, is observed for various load-sharing rules except in the globally mean field theory. The evolution according to the cluster load-sharing rule, which reflects the interaction between broken clusters, cannot be predicted by a simple criterion from the initial damage pattern and even then is most complicated. (2) A binary failure probability, its transitional region, where globally stable (GS) modes and evolution-induced catastrophic (EIC) modes coexist, and the corresponding scaling laws are fundamental to the failure. There is a sensitive zone in the vicinity of the boundary between the GS and EIC regions in phase space, where a slight stochastic increment in damage can trigger a radical transition from GS to EIC. (3) The distribution of strength is obtained from the binary failure probability. This, like sample-specificity, originates from a trans-scale sensitivity linking meso-scopic and macroscopic phenomena. (4) Strong fluctuations in stress distribution different from that of GS modes may be assumed as a precursor of evolution-induced catastrophe (EIC).