[Colección de fotografías de viajes] [ [Material gráfico]: [París, Hamburgo, Madrid y Barcelona].

[1]. Estación del Norte en Valencia, 1930 (1 fot.) – [2]. París, Manolo Orrico Vidal junto al río Sena, al fondo la Torre Eiffel, 1930 (1 fot.) – [3]. París, bifurcación del río Sena, 1930 (1 fot.) – [4]. Vista de la Torre Eiffel, 1930 (1 fot.) – [5-8]. Varias fotos en la Torre Eiffel: Manolo Orrico Vidal en la terraza de la Torre y en el paseo bajo la Torre, Francisco Roglá López sentado en un banco en la terraza de la Torre lleva paraguas y sombrero, 1930 (4 fot.) – [9]. Museo del Louvre (1 fot.) – [10]. Plaza de la Concorde (1 fot.) – [11]. Notre Dame (1 fot.) – [12]. Manolo Orrico Vidal en una terraza donde se ve una panorámica de la ciudad de Paris, en el cartel se lee Musée Grévin (1 fot.) – [13-14]. Iglesia de la Madeleine, Manolo Orrico Vidal en la escalinata de Iglesia (2 fot.) – [15]. Gran Palacio de París situado en los Campos Elíseos (1 fot.) – [16]. Palacio del Descubrimiento (1 fot.) – [17]. El Arco de Triunfo del Carrusel (1 fot.) – [18]. Palacio del Trocadero, 1930 (1 fot.) – [19]. Jardín de las Tullerias, Manolo Orrico Vidal junto a la escultura Le Nil, 1930 (1 fot.) – [20]. Plaza del Châtelet con la Fuente de la Palmera (1 fot.) – [21]. Plaza sin identificar (imagen borrosa) (1 fot.) – [22]. Manolo Orrico Vidal sentado en un banco en la plaza junto a la Torre medieval de Saint Jacques (1 fot.) – [23]. Manolo Orrico Vidal con un amigo bajo un conjunto escultórico (La Danza, de Carpeaux) a la entrada de la Ópera de París (1 fot.) – [24]. Plaza de la República con el monumento (1 fot.) – [25]. Manolo Orrico Vidal con un amigo en una plaza sin identificar (1 fot.) – [26]. Manolo Orrico Vidal junto a la fuente en el patio del Ayuntamiento de Hamburgo (1 fot.) – [27-29]. Vista de Hamburgo desde el barco con S. Michelle al fondo, Francisco Roglá López sentado en una butaca de mimbre en el barco (3 fot.) – [30]. Lieja, 1930 Fuente de la Virgen situada en rue des dominicains, erigida en 1584 y coronada por la estatua de bronce de la Virgen y el Niño, realizada en 1696 por el escultor Jean Delcour(1 fot.) – [31]. Hamburgo 1930, Denkmal Kaiser Wilhem en Rathausmarkt (1 fot.) – [32]. Manolo Orrico Vidal junto al lateral derecho del monumento al Káiser Wilhem (1 fot.) – [33-34]. Palacio Real de Madrid, durante un desfile y vista de la fachada sur, 1930 (2 pares estereoscópicos) (2 fot.) – [35-38]. Parque Güell de Barcelona, 1930 (4 pares estereoscópicos) (4 fot.)

Double-level “orthogonal” dynamic combinatorial libraries on transition metal template

Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain components to a molecular target. We present here an extension of this initial concept to dynamic libraries that consists of two levels, the first formed by the coordination of terpyridine-based ligands to the transition metal template, and the second, by the imine formation with the aldehyde substituents on the terpyridine moieties. Dialdehyde 7 has been synthesized, converted into a variety of ligands, oxime ethers L11–L33 and acyl hydrazones L44–L77, and subsequently into corresponding cobalt complexes. A typical complex, Co(L22)22+ is shown to engage in rapid exchange with a competing ligand L11 and with another complex, Co(L22)22+ in 30% acetonitrile/water at pH 7.0 and 25°C. The exchange in the corresponding Co(III) complexes is shown to be much slower. Imine exchange in the acyl hydrazone complexes (L44–L77) is strongly controlled by pH and temperature. The two types of exchange, ligand and imine, can thus be used as independent equilibrium processes controlled by different types of external intervention, i.e., via oxidation/reduction of the metal template and/or change in the pH/temperature of the medium. The resulting double-level dynamic libraries are therefore named orthogonal, in similarity with the orthogonal protecting groups in organic synthesis. Sample libraries of this type have been synthesized and showed the complete expected set of components in electrospray ionization MS.

Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice

Tissue kallikrein is a serine protease thought to be involved in the generation of bioactive peptide kinins in many organs like the kidneys, colon, salivary glands, pancreas, and blood vessels. Low renal synthesis and urinary excretion of tissue kallikrein have been repeatedly linked to hypertension in animals and humans, but the exact role of the protease in cardiovascular function has not been established largely because of the lack of specific inhibitors. This study demonstrates that mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The heart exhibits septum and posterior wall thinning and a tendency to dilatation resulting in reduced left ventricular mass. Cardiac function estimated in vivo and in vitro is decreased both under basal conditions and in response to βadrenergic stimulation. Furthermore, flow-induced vasodilatation is impaired in isolated perfused carotid arteries, which express, like the heart, low levels of the protease. These data show that tissue kallikrein is the main kinin-generating enzyme in vivo and that a functional kallikrein–kinin system is necessary for normal cardiac and arterial function in the mouse. They suggest that the kallikrein–kinin system could be involved in the development or progression of cardiovascular diseases.

North American starfishes / by Alexander Agassiz.

v.5:no.1 (1877)

Letter from Thomas Giraud to William Tudor,

One letter mentioning the French ambassador to Naples, Charles Jean-Marie Alquier. In French.

The Kansas Pacific Railway and its relations to the Union Pacific Railroad and the government of the United States.

Signed: L.H. Meyer, chairman.

Citizen volunteers in traffic safety programs: a preliminary survey. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Le tombeau : (Sonate) : [oeuvre 5, no. 6] /

Mode of access: Internet.

L'Exemplarisme divin selon Saint Bonaventure,

Issued also, in part, as thesis (Fribourg) under title: Des idées exemplaires en Dieu d'aprés Saint Bonaventure.

La préparation évangélique.

[1] Introduction génŕale. Livre I.--[2] Livres II-III.--[3] Livres IV-V, 1-17.--[4] Livres V, 18-26-VI.--[5] Livre VII.--[6] Livres VIII-IX-X.--[7] Livre XI.--[8] Livres XII-XIII.--[9] Livres XIV-XV.

Zeitschrift für Krystallographie und Mineralogie.

Mode of access: Internet.