Estratégias para administração segura de antineoplásicos

Pós-graduação em Enfermagem - FMB

Testes para avaliação das funções cognitivas de memória e aprendizado em cães

Animais idosos podem mostrar dificuldades de aprendizagem e queda no desempenho de atividades que exigem a memória. O declínio no aprendizado e na memória pode ser demonstrado em cães já aos 7 anos de idade, usando uma variedade de testes neuropsicológicos. Diferentes testes vêm sendo desenvolvidos para avaliar o aprendizado e os diferentes sistemas de memória em cães, os quais são uma medida mais objetiva e mais sensível que a avaliação do dono, já que mensuram o aprendizado e a memória ao invés de observações clínicas. Por meio do uso destas provas, muitos avanços têm sido realizados no entendimento da disfunção cognitiva em animais de companhia e no desenvolvimento de agentes terapêuticos que sejam efetivos no aperfeiçoamento do aprendizado e da memória e no tratamento da síndrome da disfunção cognitiva em cães idosos. O presente trabalho tem como objetivo dissertar acerca da execução de diferentes testes cognitivos que vêm sendo realizados em cães, o tipo de memória avaliada por estes e expor alguns resultados obtidos com experimentos prévios.

Acompanhante terapêutico: caracterização da prática profissional na perspectiva da Análise do Comportamento

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação farmacognóstica qualitativa das folhas do vegetal Bambusa textilis

Introduction: Bamboos belong to the family Graminae, Bambusoidae subfamily, represented by about 1,250 species worldwide. Originally employed in construction and power, are currently the subject of investigations related to its therapeutic properties in neoplasms. The main species used for therapeutic purposes based on popular knowledge are: Phyllostachys nigra; Bambusa breiflora; tuldoides Bambusa textilis and Bambusa. The literature on the therapeutic action of bamboo species is scarce, but recent studies report a promising effect in the treatment of cancer and other chronic diseases. Objective: This study aimed to evaluate qualitatively the phytochemical composition of plant extract obtained from the leaves of the bamboo species Bambusa textilis, comparing this composition from vegetable leaves with 18 and 24 months of age. Methodology: After collecting plant leaves with 18 or 24 months, they were identified and submitted to drying and milling. For qualitative analysis of its components were employed methods of macroscopic evaluation (mucilage), method of benzoin (resin), reaction Shinoda (flavonoids), reaction with gelatin solution (tannins), boiling and foaming (saponins) and jobs of reactive Wagner, Bertrand, Dragendorff, Mayer, picric acid and tannic acid (alkaloids) (Biavatti; MILK, 2007). Results: in the youngest leaves were found positive for alkaloids, flavonoids, resins and saponins. In the leaves of the plant with 24 months were found only alkaloids flavonoids and resins. Conclusion: the composition of vegetable substances were found associated with a significant therapeutic potential difference and the phytochemical composition in comparison with plant leaves 18 or 24 months. Additional studies are needed to quantify these components, as well as the clarification of its action in the fight against cancer and chronic diseases.

Síntese e caracterização de matrizes híbridas para aplicação em sistemas de liberação controlada

Pós-graduação em Ciência dos Materiais - FEIS

Efeitos da associação dos tratamentos de crioterapia e ultrassom terapêutico na reparação da lesão muscular de ratos wistar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Novas alternativas terapêuticas para o tratamento da Criptococose: análogos de Resveratrol e microRNAs

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo químico e biológico dos fungos endofíticos Microascus sp. e Nodulisporium sp. associados à alga vermelha Asparagopsis Taxiformis

Pós-graduação em Química - IQ

Use of music and play in pediatric nursing care in the hospital context

Objective. To identify and analyze scientific publications on the use of music and play in pediatric nursing care in the hospital context. Method. In this bibliographic study, papers were sought that were published in Portuguese or English between 2004 and 2009 and included the descriptors: hospitalized child, childhood, child recreation, nursing team, nursing, pediatric nursing, alternatives therapies, music, music therapy, play and playthings, play therapy, playing. For the review, the bibliographic databases used were MEDLINE, ScIELO and LILACS. Results. Seventeen publications were obtained, among which: 59% adopted a quantitative method; mainly nursing developed the activities (88%); per type of article, reviews on the theme and assessments of clinical changes associated with the use of music and play were frequent (59% and 18%, respectively); and the utility of this kind of therapies in nursing care is acknowledged (94%). Conclusion. Play and music are useful therapies that can be used in nursing care for pediatric patients.

Importância da segregação de materiais no gerenciamento de lixo hospitalar na área de hemoterapia

In recent years the environment and its effects on human life has been the subject of research. The scientific society organized to manage the problem of large amount of waste generated, discuss the degradation of the environment and point out possible solutions. The scarcity of references in the specific hemotherapy motivated this research. This study is an observational descriptive in order to raise the issue of hospital waste specific area of hemotherapy, presenting its latest ratings on Brazilian law also highlights the proposed Waste Management Program Health Service (PGRSS) Blood Center of Botucatu (HB) highlighting the importance of segregation of noble material in the generation of other therapeutic products using the technique of cleaner production (CP). The observational analysis of the reports shows a 20-fold increase in the amount of waste generated from 1993 to 2005, while the increase of manpower was 2.5 times. The increase in generation was due RSS hemocenter deployment of automated techniques, increased demand and improved sorting of waste. The technique implanted P + L in 2001 began using units of fresh frozen plasma, previously discarded after 12 months of storage, for the composition of new therapeutics for topical use, called bio dressing. In 10 years of implementation of this new technique, therapeutic products generated 535 patients benefited from micro-Botucatu.

Caracterização morfológica, perfil químico, atividade biológica e conservação in situ do gênero Lychnophora Mart. (Asteraceae: Vernonieae: Lychnophorinae), Brasil

Many people who live in the cerrado regions use plant species for therapeutic purposes. However, due to intensive extraction of some species, native botanical populations are at risk of disappearing or suffering a dramatic decrease, such as, for instance, individuals of the Lychnophora genus. This has 24 species distributed into the categories vulnerable, endangered, critically endangered, and possibly extinct. These individuals are known in folk medicine as “arnica” and their leaves and flowers are commonly used as anti-inflammatory, analgesic, and healing agents. The chemical profile of the genus is characterized by the presence of sesquiterpene lactones, sesquiterpenes, diterpenes, triterpenes, flavonoids, steroids, polyacetylenes, and caryophyllene derivatives which also have lignans with analgesic activity. Studies with Lychnophora species show significant results with regard to their biological activities against Leishmania amazonensis, Staphylococcus aureus, and Tripanosoma cruzi. Therefore, this study aimed to perform a survey of the morphology, chemical composition, and biological activity, as well as the use and current conservation status of the Lychnophora genus in Brazil.

Limites reais e impostos à criança com subvisão: a contribuição do design para o projeto de jogos inclusivos

Pós-graduação em Design - FAAC

Aplicação de objetos de uso cotidiano em ambiente lúdico e o impacto do design em sua adoção

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análises celulares e moleculares dos efeitos do peptídeo vasoativo angiotensina-(1-7) no processo tumoral pulmonar e a atuação do microrna 21-5P

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Inibição da metástase via transição epitélio-mesenquimal por shRNA, metformina e Y27632 em neoplasia mamária

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)