Properties of debris flow deposits and source materials compared: implications for debris flow characterization

In the Alps, debris flow deposits generally contain < 5% clay-size particles, and the role of the surface-charged < 2 mu m particles is often neglected, although these particles may have a significant impact on the rheological properties of the interstitial fluid. The objective of this study was to compare debris flow deposits and parent materials from two neighbouring catchments of the Swiss Alps, with special emphasis on the colloidal constituents. The catchments are small in area (4 km(2)), 2.5 km long, similar in morphology, but different in geology. The average slopes are 35-40%. The catchments were monitored for debris flow events and mapped for surface aspect and erosion activity. Debris flow deposits and parent materials were sampled, the clay and silt fractions extracted and the bulk density, < 2 mm fraction bulk density, particle size distribution, chemical composition, cation exchange capacity (CEC) and mineralogy analysed. The results show that the deposits are similar to the parent screes in terms of chemical composition, but differ in terms of: (i) particle size distribution; and (ii) mineralogy, reactivity and density of the < 2 mm fraction. In this fraction, compared with the parent materials the deposits show dense materials enriched in coarse monocrystalline particles, of which the smallest and more reactive particles were leached. The results suggest that deposit samples should not be considered as representative of source or flow materials, particularly with respect to their physical properties.

Generation of a tightly regulated all-cis beta cell-specific tetracycline-inducible vector.

Ability to induce protein expression at will in a cell is a powerful strategy used by scientists to better understand the function of a protein of interest. Various inducible systems have been designed in eukaryotic cells to achieve this goal. Most of them rely on two distinct vectors, one encoding a protein that can regulate transcription by binding a compound X, and one hosting the cDNA encoding the protein of interest placed downstream of promoter sequences that can bind the protein regulated by compound X (e.g., tetracycline, ecdysone). The commercially available systems are not designed to allow cell- or tissue-specific regulated expression. Additionally, although these systems can be used to generate stable clones that can be induced to express a given protein, extensive screening is often required to eliminate the clones that display poor induction or high basal levels. In the present report, we aimed to design a pancreatic beta cell-specific tetracycline-inducible system. Since the classical two-vector based tetracycline-inducible system proved to be unsatisfactory in our hands, a single vector was eventually designed that allowed tight beta cell-specific tetracycline induction in unselected cell populations.

Vehicular Traffic Flow Map, 1988

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 1990

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 1992

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 1994

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 1996

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 1998

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 2000

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 2002

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 2004

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 2006

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Vehicular Traffic Flow Map, 2008

Traffic volumes represented on this map are annual average daily traffic volumes between major traffic generators: highway junctions and cities.

Interstate Route Flow Map, 1992

Interstate Route Flow represented on this map are annual average daily traffic volumes between major traffic.

Interstate Route Flow Map, 1994

Interstate Route Flow represented on this map are annual average daily traffic volumes between major traffic.