Carbohydrate and glutamine supplementation modulates the Th1/Th2 balance after exercise performed at a simulated altitude of 4500 m

Objective: The aim of this study was to evaluate the effect of carbohydrate or glutamine supplementation, or a combination of the two, on the immune system and inflammatory parameters after exercise in simulated hypoxic conditions at 4500 m.Methods: Nine men underwent three sessions of exercise at 70% VO2(peak) until exhaustion as follows: 1) hypoxia with a placebo; 2) hypoxia with 8% maltodextrin (200 mL/20 min) during exercise and for 2 h after; and 3) hypoxia after 6 d of glutamine supplementation (20 g/d) and supplementation with 8% maltodextrin (200 mL/20 min) during exercise and for 2 h after. All procedures were randomized and double blind. Blood was collected at rest, immediately before exercise, after the completion of exercise, and 2 h after recovery. Glutamine, cortisol, cytokines, glucose, heat shock protein-70, and erythropoietin were measured in serum, and the cytokine production from lymphocytes was measured.Results: Erythropoietin and interleukin (IL)-6 increased after exercise in the hypoxia group compared with baseline. IL-6 was higher in the hypoxia group than pre-exercise after exercise and after 2 h recovery. Cortisol did not change, whereas glucose was elevated post-exercise in the three groups compared with baseline and pre-exercise. Glutamine increased in the hypoxia + carbohydrate + glutamine group after exercise compared with baseline. Heat shock protein-70 increased post-exercise compared with baseline and pre-exercise and after recovery compared with pre-exercise, in the hypoxia carbohydrate group. No difference was observed in IL-2 and IL-6 production from lymphocytes. IL-4 was reduced in the supplemented groups.Conclusion: Carbohydrate or glutamine supplementation shifts the T helper (Th)1/Th2 balance toward Th1 responses after exercise at a simulated altitude of 4500 m. The nutritional strategies increased in IL-6, suggesting an important anti-inflammatory effect. (C) 2014 Elsevier Inc. All rights reserved.

Projeto de um dispositivo para prensar bobinas polares de pólos salientes para hidrogeradores

The increasing demand for productivity and quality in companies has converged to a common point: reducing costs. In this context the present work aims at the development of a mechanical press which is designed for pressing polar hydrogenerators coils with salient pole in field facilitating the assembly of the poles in the plant, as well as reforms especially in hydrogenerators, reducing significantly the transport costs. With security in mind as well as reduced costs, a study was made of the materials to be used as it was applied a methodology for calculating the correct choice of safety factor to be used in the device. Through mechanical calculations were dimensioned critical items of the device as the diameter of the rods as well as the minimum thickness of the base of the device must have so that it does not break threaded shear in the region by applying the total load of traction on the risers implementation of the pressing. All compression loading device will be through the application of torque on the nuts of bolts in this way was defined by calculations the required torque for each nut so that you can reach the pressure specified in the design specifies. The modeling of the device was made using the INVENTOR™ program in conjunction with the program ANSYS ™. These programs have created designs in three dimensions, assembly and simulation of stress analysis in components of the device

Isoeritrólise neonatal eqüina

Equine neonatal isoerythrolysis is a neonatal foals’ illness. Results from the incompatibility of blood type between the foal and the mare and mediated by maternal antibody absorbed by the colostrum against foal’s red blood cells. Characterized by a type ll hypersensitivity reaction, where the exhibition of the organism to a strange antigen, that it takes the sensitization of the lymphocytes B that after the removal of the antigens by the reticule-endothelial system the production of immunoglobulin is decreased, with the formation of cellular immunological will cause the occurrence of the illness in foal of sensitized mares. The most important clinical signs are severe anemia and jaundice, and this illness should be differentiated of other as: hemolysis induced by bacterial toxins, diseases of the hepatobiliary system, disseminated intravascular coagulation and incompatibility in blood transfusions. Like the sensitization happens during the previous incompatible foal’s birth, most cases occur in foals of multiparous mares. However during the first pregnancy the mare can generate a foal with neonatal 7 isoerythrolysis if she have developed placental anomaly in the beginning of the pregnancy which blood cells in her circulation

Efeitos da adição de mananoproteínas derivadas da parede celular de leveduras sobre parâmetros imunológicos de cães adultos e idosos

Pós-graduação em Medicina Veterinária - FCAV

Mites (Arthropoda: Acari) associated with three species of the genus Jatropha (Euphorbiaceae) in Brazil, with emphasis on Jatropha curcas L.

The physic nut (Jatropha curcas L.) (Euphorbiaceae) has emerged as a new option in cultivation aimed at biodiesel production. In order to provide information that may be useful to further develop management plans for that specific crop, samples of mites were collected from cultured and wild J. curcas plants in various regions of the country and from two other species of the same genus, Jatropha gossypiifolia L. and Jatropha mollissima (Pohl) Baill. in the northeastern region of Brazil. Altogether 31 species belonging to 10 families were recorded. The family Phytoseiidae presented the largest number of species (17). Polyphagotarsonemus latus Banks (Tarsonemidae) was the most abundant species (8,503 specimens). A dichotomous key was prepared to identify all the sampled species. At least four mite species of the samples deserve attention as showing potential for being pests in the crops of J. curcas, Brevipalpus phoenicis, Brevipalpus obovatus, Polyphagotarsonemus latus and Tetranychus bastosi, the latter two often found in great abundance.

Planejamento e controle da produção: reestruturação no layout de apertadeiras eletrônicas em uma linha de produção do ramo de autopeças

In industrial plants, there is a department responsible for planning the use of productive resources to find the best possible way to set out plans in strategic, tactical and operational levels. This department is known as PCP or PPCP, which means Planning and Production Control and Planning, Programming and Production Control, respectively. This work presents the use of some of the tools from this department, in particular the Aggregate Production Planning, to propose a new layout of electronic nutrunners for an auto parts industry output line. Through some process indicators analyzes, was identified some productivity losses. The higher loss rate occurred by the electronic nutrunners breaking, and so this work was focused in these devices. Some premises were adopted for the use of electronic nut runners, setting an ideal cycle time for the operation of the production line and making calculations to define the minimum amount of electronic nutrunners to find the production demand without damaging the equipment. With this work we observed that a relevant factor for the constant breaks of electronic nutrunners is because these are working with overload, in other words, the amount of installed equipment is not enough to supply the demand without failures

Estudo clínico longitudinal de dentes restaurados com sistemas cerâmicos livres de metal: estudo prospectivo sobre a hipersensibilidade dental pós-operatória

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Subepithelial connective tissue graft: a case report

Introduction and objective: Marginal tissue recession represents a common condition in Periodontology. Miller's Classes I and II recessions, in which the etiological factors are well diagnosed and eliminated, show great predictability of total coverage when the technique of subepithelial connective tissue graft is used. This technique success has been mainly attributed to the double blood supply for graft's nutrition, originating from the connective tissue of both the periosteum and flap. Case report and conclusion: The authors reported a clinical case in which a Miller's Class I recession was treated by the surgical technique of subepithelial connective tissue graft, obtaining total coverage, eliminating the aesthetic deficiency and the dentin hypersensitivity complained by patient.

Importância do tratamento estético periodontal na reabilitação protética

Gingival recession is a common deformity that affects a large number of people. This condition is frequently associated with esthetic complains and may lead to dental hypersensitivity. Thus, various surgical procedures have been proposed to provide root coverage. Since the 1950s, free and pedicle gingival grafts have been greatly used for treating gingival recession. However, after the 1985 Miller gingival recession classification, and with the development of other appropriated techniques that use subepithelial connective tissue grafts, gingival recession treatments have resulted in more predictable outcomes, especially with respect to Class I and II sites, i.e., in the absence of interproximal bone loss. This article reported the importance of aesthetical periodontal treatment in the prosthetic rehabilitation of a patient with a class I gingival recession with 3 mm of vertical extension in the superior canine. The treatment plan consisted of root coverage using subepithelial connective tissue graft (SCTG) associated with construction of new prosthesis.

Hipersensibilidade dentinária cervical: em busca de um tratamento eficaz

The knowledge of the etiology of any disease or condition is paramount to a safe and effective treatment. This literature review aims to show some options to treat dentine hypersensitivity (HSDC). The loss of cervical enamel and cementum exposure of tubules leads to a painful condition and patient discomfort, called HSDC. This loss of tooth structure occurs due to formation of cervical lesions in cases of gingival recession, abrasion, erosion, or abfraction by the association of two or more factors. Some treatments are not effective, but there are effective therapies, such as: application of ferric oxalate, potassium oxalate, potassium nitrate, fluoride varnish, solutions of calcium phosphate, adhesives and Bonding procedures. Therefore, the identification and removal of etiological factors is essential to successful treatment of HSDC normally associated to tubules obliterate and consequent reduction of fluid motion within the dentin.

Tratamento estético periodontal: revisão de literatura sobre alguns tipos de cirurgias

Currently, periodontal aesthetics has been prized for harmony of the smile. The clinical crown lengthening, gingival excess or altered passive eruption, is effectively corrected by periodontal surgery. The purpose of this paper is to show, through a literature review, some types of surgery on clinical crown lengthening and root coverage. Clinical crown lengthening is done to Change the size of the anterior teeth and to optimize the cosmetic result of treatment with new coronal restoration and other cosmetic dental care. In general, the treatment plan and the choice of operative technique begin with careful clinical examination. Recessions tissue can be defined as a displacement of the gingival margin toward the junction mucogingival exposing the root surface. These, when present, impacting on patient comfort by providing the occurrence of cervical dentin hypersensitivity, and the esthetic, the amendment of the gum line. Successful treatment of recessions is based on knowledge of its etiology and assessment of predictability of surgical techniques that aim to root coverage. Through literature review, we can conclude that the types of surgery most often used are: 1) to increase the clinical crown, gingivectomy, flap surgery and gingivoplasty osteotomy, and 2) for root coverage, the use will depend on the amount of gum keratinized and especially the classification of Miller.

Efecto del ácido oxálico bajo restauraciones cervicales en dientes con hipersensibilidad: ensayo clínico randomizado controlado doble ciego

To evaluate the effect of oxalic acid in cervical hypersensitivity, used under two different resin restorations one based on methacrylate and another based on silorane. Methods: 19 patients with “LCNC with hypersensitivity” were distributed into 4 groups according to treatment: G1 (n = 31): 0.5% oxalic acid (Desenssiv, SSWhite) + Z250 (3MESPE), G2 (n = 31): 0.5% oxalic acid + Filtek Silorane - P90 (3MESPE), G3 (n = 30): Distilled water + Z250; G4 (n = 30): Distilled water + Filtek Silorane - P90. Two clinical calibrated (kappa> 0.75) evaluated the sensitivity of the teeth: Before treatment, at 30, 60 and 90 days post-treatment (VAS). Results: The 4 groups at 30, 60 and 90 days reduced HS compared with the baseline (p <0.05). G1 and G2 showed less HS than G3 and G4 (p <0.05). Conclusion: The 4 restorative procedures significantly reduce the hypersensitivity, 30, 60 and 90 days compared to the baseline.

Importância do tratamento estético periodontal na reabilitação protética

Gingival recession is a common deformity that affects a large number of people. This condition is frequently associated with esthetic complains and may lead to dental hypersensitivity. Thus, various surgical procedures have been proposed to provide root coverage. Since the 1950s, free and pedicle gingival grafts have been greatly used for treating gingival recession. However, after the 1985 Miller gingival recession classification, and with the development of other appropriated techniques that use subepithelial connective tissue grafts, gingival recession treatments have resulted in more predictable outcomes, especially with respect to Class I and II sites, i.e., in the absence of interproximal bone loss. This article reported the importance of aesthetical periodontal treatment in the prosthetic rehabilitation of a patient with a class I gingival recession with 3 mm of vertical extension in the superior canine. The treatment plan consisted of root coverage using subepithelial connective tissue graft (SCTG) associated with construction of new prosthesis.

Erosive potencial of energy drinks on the dentine surface

Coordenação de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)

Recobrimento radicular para o tratamento de hipersensibilidade dentinária cervical persistente

Gingival recession has a high prevalence in the population. This alteration may promote several complications such as cervical dentinal hypersensitivity (HSDC), carious and non-carious cervical lesions, and cosmetic changes due to the increase of the clinical crown length. To treat HSDC there are several therapeutic possibilities that should aim to eliminate pain after external stimulus. Treatment of this alteration can be performed by a conventional or invasive procedure, depending on the clinical condition and patients' desires. In situations where aesthetics is not the main complaint and HSDC persists even after conservative procedures, it is possible to indicate a procedure to achieve root coverage in Miller's Class I and II recessions. The aim of this paper is to report a case where the HSDC was not eliminated by conventional methods, which was resolved only after performing a minimally invasive surgery that promoted total root coverage.