Recent advances in engineering topography mediated antibacterial surfaces

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria-material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces.

Peptide delta-Turn: Literature Survey and Recent Progress

Among the various types of a-peptide folding motifs, delta-turn, which requires a central cis-amide disposition, has been one of the least extensively investigated. In particular, this main-chain reversal topology has been studied in-depth neither in linear/cyclic peptides nor in proteins. This Minireview article assembles and critically analyzes relevant data from a literature survey on the d-turn conformation in those compounds. Unpublished results from recent conformational energy calculations and a preliminary solution-state analysis on a small model peptide, currently ongoing in our laboratories, are also briefly outlined.

Large Eddy Simulation of Complex Turbulent Flows: Physical Aspects and Research Trends

In the current paper, we have primarily addressed one powerful simulation tool developed during the last decades-Large Eddy Simulation (LES), which is most suitable for unsteady three-dimensional complex turbulent flows in industry and natural environment. The main point in LES is that the large-scale motion is resolved while the small-scale motion is modeled or, in geophysical terminology, parameterized. With a view to devising a subgrid-scale(SGS) model of high quality, we have highlighted analyzing physical aspects in scale interaction and-energy transfer such as dissipation, backscatter, local and non-local interaction, anisotropy and resolution requirement. They are the factors responsible for where the advantages and disadvantages in existing SGS models come from. A case study on LES of turbulence in vegetative canopy is presented to illustrate that LES model is more based on physical arguments. Then, varieties of challenging complex turbulent flows in both industry and geophysical fields in the near future-are presented. In conclusion; we may say with confidence that new century shall see the flourish in the research of turbulence with the aid of LES combined with other approaches.

An overview of air-sea interface process studies

Recent progress in the study of air-sea interface processes for momentum, heat, moisture and mass transfer are reviewed in the present article. Except for turbulent structure, we have analysed the other physical mechanisms occurring in the wave boundary layer, such as the roles of the sea surface state, droplets and bubbles due to wave breaking, which at least partly account for the existing discrepancies between theory and observations. The experiments, both over the ocean and in the laboratory, are described briefly. In conclusion, a few perspective trends in this area are suggested for further investigation.

The MBA-LBA I period in the Kourion region : new evidences from Erimi- Laonin tou Porakou (Lemesos, Cyprus)

The evidence from Erimi-Laonin tou Porakou within the Kouris valley settlement system can offer further new data to outline a picture of the development trends from MBA to LBA I periods in the Kourion region. As to this area, such a “transitional” phase could be particularly relevant to better understand the development process of the mature LBA II–III urban centers (in Alassa as well as the most recent discovered in Erimi-Pitharka). In 2008–2009 a focus investigation (an intensive survey, geoperspections and excavations) within the Kouris Valley Project has been addressed to the site of Erimi-Laonin tou Porakou, which lies on one of the highest hilltops facing southward the Kouris dam. The excavations evidenced a double circuit wall which surrounds the top mound and the lower terrace. The top mound (Area A) has been widely occupied by a complex workshop, directly linked with a storage area. The natural limestone bedrock has been worked out to arrange a system of carved deep basins connected each other by a series of flow channels. Southward from the workshop, a large storage area has been cleared, with a relevant assemblage of big pithoi and storage devices. The first lower terrace area (Area B) has been possibly occupied by a domestic quarter; a cemetery area (Area E) has been also evidenced outside the external circuit wall, where a series of five rock-cut tombs (Tombs 228– 232) with single chamber and small incoming dromoi has been excavated.

Pool Boiling In Microgravity: Recent Results And Perspectives For The Project Depa-Sj10

Two research projects on pool boiling in microgravity have been conducted aboard the Chinese recoverable satellites. Ground-based experiments have also been performed both in normal gravity and in short-term microgravity in the Drop Tower Beijing. Steady boiling of R113 on thin platinum wires was studied with a temperature-controlled heating method, while quasi-steady boiling of FC-72 on a plane plate was investigated with an exponentially increasing heating voltage. In the first case, slight enhancement of heat transfer is observed in microgravity, while diminution is evident for high heat flux in the second one. Lateral motions of bubbles on the heaters are observed before their departure in microgravity. The surface oscillation of the merged bubbles due to lateral coalescence between adjacent bubbles drives it to detach from the heaters. The Marangoni effect on the bubble behavior is also discussed. The perspectives for a new project DEPA-SJ10, which has been planned to be flown aboard the Chinese recoverable satellite SJ-10 in the future, are also presented.

Research Progress On Thermal Protection Materials And Structures Of Hypersonic Vehicles

Hypersonic vehicles represent future trends of military equipments and play an important role in future war. Thermal protection materials and structures, which relate to the safety of hypersonic vehicles, are one of the most key techniques in design and manufacture of hypersonic vehicles. Among these materials and structures, such as metallic temperature protection structure, the temperature ceramics and carbon/carbon composites are usually adopted in design. The recent progresses of research and application of ultra-high temperature materials in preparation, oxidation resistance, mechanical and physical characterization are summarized.

De los grandes relatos a los estudios de “pequeña escala” : algunas notas acerca de la historiografía del primer peronismo

Resumen: Existen varias posibilidades a la hora de analizar las distintas corrientes en la historiografía reciente del peronismo; sin embargo, en líneas generales, se puede decir que a lo largo de los años el foco del debate se ha trasladado de los sociólogos a los historiadores, de las perspectivas macro a las micro y de lo político a lo social. El énfasis inicial acerca de la supuesta ruptura y anomalía que representaba el peronismo ha prácticamente desaparecido a favor de la continuidad y de su contextualización en el proceso histórico argentino. La imagen homogénea ha sido reemplazada por un cuadro complejo y heterogéneo. Desde la perspectiva de los estudios de género, las investigaciones sobre el peronismo han producido no solamente trabajos sobre el Partido Peronista Femenino, sino otros que también han explorado temas como la reproducción, la maternidad, la infancia y las dinámicas familiares. Asimismo, la dimensión nacional, basada en la experiencia de la Capital Federal y sus alrededores, es decir la óptica metropolitana, ha dado lugar a distintas miradas provinciales, regionales y locales. Con cierta exageración se podría hablar de un desplazamiento de los grandes relatos y los modelos teóricos a los estudios de pequeña escala de la vida cotidiana bajo el peronismo.