992 resultados para Order-parameter


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Amend Executive Order #15 establishing a code of fair pratices.

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To establish the iowa Literacy council.

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Order that each department in the Executive branch undertake a comprehensive review of its supervisory span of control and report to the Inspector General.

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Set the maximum percentage of federal funds allotted to Iowa that may be spent on municipal Wastewater treatment works at 20%.

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Create an Iowa Economic Development Coordinating Committee.

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Establish the Iowa Governor's Council on Physical Fitness and Sports and meet certain objectives.

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Create an Iowa Partnership for Economic Progress.

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Create a Telecommunication and Information Management Council.

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Order a 3.85% reduction in appropriations.

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Declare that a state of economic emergency exists.

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Rename Iowa Refugee Service Center as Bureau of Refugee Programs and place it administratively in the Department of Human Services.

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Provide a method of allocating the total amount of bonds which may be issued with the State in any calender year among the various polictical subdivisions an issuing agencies and authorities of the State.

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BACKGROUND: Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations are associated with failure of prophylaxis with sulfa drugs. This retrospective study sought to better understand the geographical variation in the prevalence of these mutations. METHODS: DHPS polymorphisms in 394 clinical specimens from immunosuppressed patients who received a diagnosis of P. jirovecii pneumonia and who were hospitalized in 3 European cities were examined using polymerase chain reaction (PCR) single-strand conformation polymorphism. Demographic and clinical characteristics were obtained from patients' medical charts. RESULTS: Of the 394 patients, 79 (20%) were infected with a P. jirovecii strain harboring one or both of the previously reported DHPS mutations. The prevalence of DHPS mutations was significantly higher in Lyon than in Switzerland (33.0% vs 7.5%; P < .001). The proportion of patients with no evidence of sulfa exposure who harbored a mutant P. jirovecii DHPS genotype was significantly higher in Lyon than in Switzerland (29.7% vs 3.0%; P < .001). During the study period in Lyon, in contrast to the Swiss hospitals, measures to prevent dissemination of P. jirovecii from patients with P. jirovecii pneumonia were generally not implemented, and most patients received suboptimal prophylaxis, the failure of which was strictly associated with mutated P. jirovecii. Thus, nosocomial interhuman transmission of mutated strains directly or indirectly from other individuals in whom selection of mutants occurred may explain the high proportion of mutations without sulfa exposure in Lyon. CONCLUSIONS: Interhuman transmission of P. jirovecii, rather than selection pressure by sulfa prophylaxis, may play a predominant role in the geographical variation in the prevalence in the P. jirovecii DHPS mutations.

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Desingation of the State Department of Public Safety as the State Highway Safety Agency and the Commissinoer of Public Safety as the Governor's representative for Highway Safety.

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Delegate to the Department of Economic Development the aithority and responsibility vested in the Governor under the JTPA, and create the State Job Training Coordinating Council.