Nixon's Cheshire prophencies; a new and complete edition, reprinted from the best sources, with an introductory essay on popular prophencies, and an appendix containing the legend of Alderley edge, a bibliography, & c. ...

"Nixon bibliography": p. 67-68.

Specimen philosopho-criticum continens diatriben de Bione Borysthenita /

Proefschrift Leiden.

Léonidas, tragédie en cinq actes.

Mode of access: Internet.

[Xenophōntos kyrou paideias biblia oktō]

Title vignette (port.)

Spicilegiorum historico-chronologicorum libri tres : quibus chronologia sacra origines et fata regnorum per orientem ut et Graecorum migrationes exhibentur : accedunt dissertationes duae de Ptolemao Aulete et vita Salvatoris publica et privata /

Mode of access: Internet.

Memoirs of odd adventures, strange deliverances, &c. in the captivity of John Gyles, Esq; commander of the garrison on St. George's River /

"Erratum."--p. [44].

Leonidas. A poem ...

Mode of access: Internet.

Herod and Mariamne.

Mode of access: Internet.

Shakespeare's King Henry V; with preface, glossary, &c.

"First ed. ...printed May 1895.

Les fabulistes latins depuis le siècle d'Auguste jusqu'à la fin du moyen âge.

v. 1-2: 2 éd. entièrement refondue.

Demosthenes : the first Philippic /

Includes bibliographical references.

The impact of peginterferon alfa-2a plus ribavirin combination therapy on health-related quality of life in chronic hepatitis C

Background/Aims: Peginterferon alfa-2a plus ribavirin improves sustained virological responses compared with interferon alfa-2b and ribavirin, or peginterferon alfa-2a alone in chronic hepatitis C. We examined the impact of these treatments on health related quality of life (HRQOL). Methods: Patients (n = 1121) were randomized to peginterferon alfa-2a weekly plus ribavirin or placebo, or interferon alfa-2b thrice weekly plus ribavirin. HRQOL was assessed with the SF-36 Health Survey and Fatigue Severity Scale (FSS). Results: Patients receiving peginterferon alfa-2a plus ribavirin reported better HRQOL than those receiving interferon alfa-2b plus ribavirin. These differences were statistically significant for three SF-36 domains and both FSS scores (p < = 0.05). Patients receiving peginterferon alfa-2a plus placebo had the least impairment; adding ribavirin significantly decreased five domains of the SF-36 and both FSS scores. Sustained virological response was associated with improvement at follow-up on all SF-36 and FSS scores. Conclusions: The effects of combination therapy on HRQOL and fatigue are less with peginterferon alfa-2a plus ribavirin than interferon alfa-2b plus ribavirin. Each medication in combination therapy with interferon and ribavirin, affects patients' quality of life differently. Understanding the relationship of specific therapeutic options to HRQOL may help physicians minimize the impact of therapy on HRQOL. (C) 2004 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

[Map of part of S.E. Washington D.C. now occupied by the Navy Yard and adjacent squares].

Covers area bounded by Anacostia River waterfront, 10th, L, and 5th streets S.E.

[Map of part of the Washington Canal at the eastern end of the Mall, Washington D.C.].

Shows "Present direction of the Canal" and "New canal."

Expression pattern of Oct-4, Sox2, and c-Myc in the primary culture of human dental pulp derived cells

Dental pulp cells (DPCs) have shown promising potential in dental tissue repair and regeneration. However, during in vitro culture, these cells undergo replicative senescence and result in significant alteration in cell proliferation and differentiation. Recently, the transcription factors of Oct-4, Sox2, c-Myc, and Klf4 have been reported to play a regulatory role in the stem cell self-renewal process, namely cell reprogramming. Therefore, it is interesting to know whether the replicative senescence during the culture of dental pulp cells is related to the diminishing of the expression of these transcription factors. In this study, we investigated the expression of the reprogramming markers Oct-4, Sox2, and c-Myc in the in vitro explant cultured dental pulp tissues and explant cultured dental pulp cells (DPCs) at various passages by immunofluorescence staining and real-time polymerase chain reaction analysis. Our results demonstrated that Oct-4, Sox2, and c-Myc translocated from nucleus in the first 2 passages to cytoplasm after the third passage in explant cultured DPCs. The mRNA expression of Oct-4, Sox2, and c-Myc elevated significantly over the first 2 passages, peaked at second passage (P < .05), and then decreased along the number of passages afterwards (P < .05). For the first time we demonstrated that the expression of reprogramming markers Oct-4, Sox2, and c-Myc was detectable in the early passaged DPCs, and the sequential loss of these markers in the nucleus during DPC cultures might be related to the cell fate of dental pulp derived cells during the long-term in vitro cultivation under current culture conditions.