992 resultados para Michel Marc Bouchard
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In this master s thesis I intend to carry out an interpretation of Michel Foucault s thought that points out the relations and theoretical, conceptual and thematic consequences with sociology in his work and theoretical propositions. For my argumentation and analysis I take as a base a specific part of his thought: the problem of domination in modern societies in the genealogic texts in the decade of 1970. It s about to identify how Foucault does his analysis of the relations of domination and the use of the power with the objective to suggest and point out his contribution to sociological analysis of domination. I will discuss the foucaultian program of the study of domination from four units of analysis: person constitution, knowledge, power and truth. The structure and division of the chapters will follow the specific and detailed study of each of those units of analysis, prioritizing their theoretical sense and consequences to the sociology. Thus, in the first chapter, I will highlight a little more the relations of affinity and the convergences between Foucault and the sociology in a way to offer more elements to justify the general objectives that this work intends to achieve. In the second chapter, I will analyze the subject of domination in Foucault s thought, discussing his basic presuppositions and its intrinsic relation with the heart of the foucaultian philosophical project, the person constitution. In turn, in the third and fourth chapter, I will discuss the interdependence between knowledge and power as an essential and opaque dimension of the ways of modern domination. In the fifth chapter, I will analyze the relation between domination and the truth discourse production
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The leitmotif of this dissertation research is on the relationship between two fields of questioning in the Foucauldian works that may be considered, at a first glance, irreconcilable: the understanding of subject as the result of determinations, on the one hand, and its ethical stance of seeking the creation of liberty, on the other. Since, despite this apparent inconsistency, both ideas are present with much emphasis on the work of the French thinker, to understand the way Foucault articulated these two ideas was necessary to elucidate and interrelate the way in which he thought about the concepts of subject, power and liberty. Traveling with the author his intellectual itinerary, it was revealed that his conception of subject and liberty can be reconciled (although maintaining its problematic nature) and, also, both are inextricably linked each one as a result of the other. Tracing, with the author, his intellectual itinerary, it was also possible to identify and describe the fruitful conceptual tools for thinking about our own determinations and about the possibilities we have of creating new subjectivities and liberating experiences
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This present research aims to understand the concept of homosexuality as a social creation that comes permeated by the discourses of sexuality devices. It discusses the issue of homosexuality with a focus on works of Michel Foucault, in special The History of Sexuality, where the author emphasizes that homosexuality as a social construct that manifests itself during the nineteenth century. From the Foucauldian discourse, it is proposed to understand and analyze the creation of the concept of homosexuality, which is built around the subordination of the individual as a social agent, or the creation of homosexuality does not refer to sexual intercourse between individuals of the same sex, but a social subject and the position it takes in society. So along with the birth of the homosexual individual, there is also the construction of the individual as a social subject, as being, homosexuality and homosexual subject are products of overlapping powerculture. When addressing this theme, it breaks the hegemony that seeks to characterize naturalized of sexuality and, consequently, homosexuality, born with the original speeches on medical and psychiatric couches, in which one perceives the role of power in the discourses deploying the truths aimed at sexuality. With this, there has been an argument that seeks to refute the eugenics that includes sexuality as something natural, instituting a homosexual as a guy born hostage to a bad genetic and abnormal who should be treated for their disease, and understand this individual as a product of social discourse
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Conselho Nacional do Desenvolvimento Científico e Tecnológico (CNPq)
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Dengue virus is a mosquito-borne flavivirus that has a large impact in global health. It is considered as one of the medically important arboviruses, and developing a preventive or therapeutic solution remains a top priority in the medical and scientific community. Drug discovery programs for potential dengue antivirals have increased dramatically over the last decade, largely in part to the introduction of high-throughput assays. In this study, we have developed an image-based dengue high-throughput/high-content assay (HT/HCA) using an innovative computer vision approach to screen a kinase-focused library for anti-dengue compounds. Using this dengue HT/HCA, we identified a group of compounds with a 4-(1-aminoethyl)-N-methylthiazol-2-amine as a common core structure that inhibits dengue viral infection in a human liver-derived cell line (Huh-7.5 cells). Compounds CND1201, CND1203 and CND1243 exhibited strong antiviral activities against all four dengue serotypes. Plaque reduction and time-of-addition assays suggests that these compounds interfere with the late stage of viral infection cycle. These findings demonstrate that our image-based dengue HT/HCA is a reliable tool that can be used to screen various chemical libraries for potential dengue antiviral candidates. © 2013 Cruz et al.
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Pós-graduação em Educação Escolar - FCLAR
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Engenharia Mecânica - FEG
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Pós-graduação em História - FCLAS
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Pós-graduação em Ciência da Informação - FFC