Violations of free speech and rights of labor : Hearings before a subcommittee of the Committee on Education and Labor, United States Senate, Seventy-fourth Congress, second session[--Seventy-sixth Congress, third session] pursuant to S. Res. 266.

Robert M. LaFollette, Jr., chairman of subcommittee.

National practices for the operation and protection of school zones and crossings; an informational report by Committee on Traffic, Subcommittee on Traffic Control Devices in cooperation with Colorado Department of Highways.

Cover title.

Business under the new price laws; a study of the economic and legal problems arising out of the Robinson-Patman Act and the various fair trade and unfair practices laws,

"Table of cases": p. [441]-447.

Consular formulary : being a collection of forms and precedents for the use of Her Majesty's consular officers in the discharge of their duties under the Consular Act, the Merchantile Marine and Registration Acts, in the exercise of their notarial functions, and generally in matters connected with British shipping, trade and commerce /

Includes bibliographical references (page 249) and index.

Distinguished successful Americans of our day; containing biographies of prominent Americans now living, noteworthy as having achieved success in their chosen avocations in the various civil, military, educational, religious, industrial, commercial and other lines of human effort--men of thought and men of action who have been effective in the establishment and maintenance of our commonwealth, prominent citizens in all walks of life who are really the founders, makers and builders of our great republic as manifested in America's great institutions of finance, commerce and trade, and its unparalleled progress in education, literature, art, science, and in the development of our nation in all lines of human endeavor.

Mode of access: Internet.

Empire, trade, and armaments; an exposure.

Mode of access: Internet.

Annual statement of the trade and commerce of St. Louis

"Reported to the Merchants' Exchange." (varies)

Index to consular reports. Index to reports of ... diplomatic and consular representatives abroad on trade and subjects of general interest. (With appendix).

1886/94-1886/96 ed. by Willoughby Maycock. 1898/99-19 ed. in the Commercial Intelligence of the Board of Trade.

Ground water contamination and protection : hearings before the Subcommittee on Toxic Substances and Environmental Oversight of the Committee on Environment and Public Works, United States Senate, Ninety-ninth Congress, first session.

"October 24, November 14, and December 12, 1985"--Pt. 2.

Annual report, containing the annual report of the Wilmington Institute Free Library and the annual report of the New Castle County Free Library.

Reports for 1893/94 and 1894/95 issued under one cover, with special title-pages.

Journal of the Commissioners for trade and plantations ...Preserved in the Public Record Office ...

Title is followed by year of issue.

World trade and investment; the economics of interdependence.

Bibliography: p.565-570.

European settlements on the west coast of Africa ; with remarks on the slave trade and the supply of cotton /

Reprint of the 1862 ed.

Trade and empire. A pamphlet for the times.

Mode of access: Internet.

Measurement of free drug and clinical end-point by high-performance liquid chromatography-mass spectrometry: Applications and implications for pharmacokinetic and pharmacodynamic studies

Free drug measurement and pharmacodymanic markers provide the opportunity for a better understanding of drug efficacy and toxicity. High-performance liquid chromatography (HPLC)-mass spectrometry (MS) is a powerful analytical technique that could facilitate the measurement of free drug and these markers. Currently, there are very few published methods for the determination of free drug concentrations by HPLC-MS. The development of atmospheric pressure ionisation sources, together with on-line microdialysis or on-line equilibrium dialysis and column switching techniques have reduced sample run times and increased assay efficiency. The availability of such methods will aid in drug development and the clinical use of certain drugs, including anti-convulsants, anti-arrhythmics, immunosuppressants, local anaesthetics, anti-fungals and protease inhibitors. The history of free drug measurement and an overview of the current HPLC-MS applications for these drugs are discussed. Immunosuppressant drugs are used as an example for the application of HPLC-MS in the measurement of drug pharmacodynamics. Potential biomarkers of immunosuppression that could be measured by HPLC-MS include purine nucleoside/nucleotides, drug-protein complexes and phosphorylated peptides. At the proteomic level, two-dimensional gel electrophoresis combined with matrix-assisted laser desorption/ionisation time-of-flight (TOF) MS is a powerful tool for identifying proteins involved in the response to inflammatory mediators. (C) 2003 Elsevier Science B.V. All rights reserved.