Gastroprotective effects (in rodents) of a flavonoid rich fraction obtained from Syngonanthus macrolepsis

Objectives: Syngonanthus macrolepis, popularly known in Brazil as sempre-vivas', is a plant from the family Eriocaulaceae, it is found in the states of Minas Gerais and Bahia. The species contains a variety of constituents, including flavonoids with gastroprotective effect. In this work, a flavonoid-rich fraction (Sm-FRF) obtained from scapes of S.macrolepis was investigated for preventing gastric ulceration in mice and rats.MethodsThe activity was evaluated in models of induced gastric ulcer (absolute ethanol, stress, non-steroidal anti-inflammatory drugs and pylorus ligation). The cytoprotective mechanisms of the Sm-FRF in relation to sulfhydryl (SH) groups, nitric oxide (NO) and antioxidant enzymes were also evaluated.Key findingsThe Sm-FRF (100mg/kg, p.o.) significantly reduced gastric injury in all models, and did not alter gastric juice parameters after pylorus ligation.ConclusionsThe results indicate significant gastroprotective activity for the Sm-FRF, which probably involves the participation of both SH groups and the antioxidant system. Both are integral parts of the gastrointestinal mucosa's cytoprotective mechanisms against aggressive factors.

Crude Glycerin associated with starch or fiber-based energy ingredients at two levels of concentrate for beef cattle

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação de uma nova composição de agente clareador sobre a microdureza do esmalte: associação do trimetafosfato de sódio e fluoreto de sódio ao peróxido de hidrogênio a 10%

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Search for massive resonances in dijet systems containing jets tagged as W or Z boson decays in pp collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for massive resonances decaying into pairs of boosted bosons in semi-leptonic final states at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for the associated production of the Higgs boson with a top-quark pair

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Measurement of prompt J/psi pair production in pp collisions at root s = 7 Tev

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Study of hadronic event-shape variables in multijet final states in pp collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for neutral MSSM Higgs bosons decaying to a pair of tau leptons in pp collisions

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Measurement of the t(t)over-bar production cross section in the dilepton channel in pp collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for exclusive or semi-exclusive gamma gamma production and observation of exclusive and semi-exclusive e(+)e(-) production in pp collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Observation of a peaking structure in the J/psi phi mass spectrum from B-+/- -> J/psi phi K-+/- decays

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Measurement of the production cross section for a W boson and two b jets in pp collisions at root s=7 TeV

The production cross section for a Wboson and two b jets is measured using proton-proton collisions at v root s = 7 TeV in a data sample collected with the CMS experiment at the LHC corresponding to an integrated luminosity of 5.0 fb(-1). The W + bbevents are selected in the W..decay mode by requiring a muon with transverse momentum pT> 25GeVand pseudorapidity |eta| < 2.1, and exactly two b-tagged jets with pT> 25GeVand |eta| < 2.4. The measured W + bbproduction cross section in the fiducial region, calculated at the level of final-state particles, is s(pp. W + bb) xB(W..) = 0.53 +/- 0.05 (stat.) +/- 0.09 (syst.) +/- 0.06 (theo.) 0.01 (lum.) pb, in agreement with the standard model prediction. In addition, kinematic distributions of the W + bbsystem are in agreement with the predictions of a simulation usingMadGraphandpythia. (C) 2014 The Authors. Published by Elsevier B. V.

Measurement of the ratio B(t -> Wb)/B(t -> Wq) in pp collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Constraints on the Higgs boson width from off-shell production and decay to Z-boson pairs

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)