Interação entre grau de perda auditiva e o incômodo com zumbidos em trabalhadores com história de exposição ao ruído

Hearing loss and tinnitus impact the lives of workers in every instance of their lives. Aim: this paper aims to investigate the existence of a dose-response relationship between hearing loss and tinnitus by determining whether higher levels of hearing loss can be associated with increased tinnitus-related discomfort. Materials and method: this cross-sectional case study assessed 284 workers exposed to occupational noise through pure tone audiometry. Test results were categorized as defined by Merluzzi. Individuals complaining of tinnitus answered the adapted and validated Brazilian Portuguese version of the Tinnitus Handicap Inventory. A generalized linear model was adjusted for binomial data to test the interaction between these factors. Results: over 60% of the ears analyzed had hearing loss, while more than 46% of them had tinnitus. Tinnitus prevalence and risk rates increased as pure tone audiometry results got worse. The association between both, considering all hearing loss degrees, was statistically significant. Conclusion: the results point to a statistical association between hearing loss and tinnitus; the greater the hearing loss, the greater the discomfort introduced by tinnitus. 2009 © Revista Brasileira de Otorrinolaringologia.

Farmacovigilância no Brasil: A relação entre polimorfismo de fármacos, efetividade e segurança dos medicamentos

In spite of the stated Brazilian policy on medicines that their quality, effectiveness and safety should be ensured at reasonable cost, hospitals in the ANVISA Surveillance Network have been receiving notifications of technical complaints, adverse reactions and suspected therapeutic ineffectiveness (STI) of medicines. The purpose of this study was to identify the medicines notified for suspicion of therapeutic ineffectiveness, at a university hospital participating in the national Surveillance Network, and to investigate the existence of polymorphs of any of the drugs involved, by examining the literature. There were 31 notifications of STI in a period of 18 months, concerning 11 different drugs, all of which were 'similar' drugs (neither original nor licensed by originator); five of these could contain polymorphs, according to the literature. However, this does not mean that the other drugs could not contain some unknown polymorphs, more studies being needed on polymorphism, especially in the cases of reported therapeutic ineffectiveness. Therefore, tests of polymorphism should be made part of the routine quality control of the raw materials during the development of medicines and in the studies of pharmaceutical equivalence to 'reference' medicines (innovative brands). The stability test should also involve a study of polymorphism, in order to confirm the solid state stability of the drug. All these measures will assure the effectiveness of medicines, since the reproducibility in the quality of pharmaceutical products could be monitored, as well as the equivalence of each production batch with the batch selected to determine the bioequivalence with the reference brand.

Situação da agricultura irrigada no Brasil de acordo com o censo agropecuário 2006

Knowledge about irrigated agricultural area and its geographical distribution are of great importance to water resources management. Evolution of irrigated area according to the irrigation method allows an identification of rational water technologies. The aim of this work was to analyze the information presented in the agricultural census of 1995/1996 and of 2006. Brazil has an area of 4.45 million cultivated hectares with irrigation. It is noticed that according to the 1995/1996 census, the irrigated area increased 1.3 million hectares, a growth of 42%. The Southeast region surpasses the South region which had, in 1995/96, the largest irrigated area. The Northeast region is the third irrigated agricultural area with 22.12 %, while the Central-west and the Northern region together sum 14.7%. According to the agricultural census 2006 classification, sprinkler irrigation (without center pivot) method is the most used,followed by flood, center pivot, other methods, drip and furrow, representing 35.3%, 24.4%, 18.9%, 8.3%, 7.4% and 5.8%, respectively.

Aspectos físicos e sociais da geografia da disponibilidade hídrica municipal no Brasil

In managing water resources, indexes are used to simplify and quantify available information as well as report the characteristics of a region under study. These indexes may be extremely demanding concerning information required, or very simple, and the water poverty index and Falkenmark index are examples of both extreme situations, respectively. Searching for an index that considers regional and local complexities and information available in developing countries, a new index was developed to evaluate the population accessibility to water resources. This new index combines the Human Development Index and Falkenmark Index and geographic information systems. The results are presented in figures which show the situation at national level, highlighting that the Northeast and Southeast regions are the most vulnerable in Brazil.

A pintura ilusionista no meio norte de Minas Gerais - Diamantina e Serro - e em São Paulo - Mogi das Cruzes (Brasil)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

História e cinema: encontro de conhecimento em sala de aula

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo de SNPs do cromossomo Y na população do Estado do Espirito Santo, Brasil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O setor sucroenergético no Brasil: Estado, hegemonia e relações internacionais - o caso da UNICA no agribusiness internacional

Pós-graduação em Ciências Sociais - FFC

Paradoxos e desafios do ensino superior no Brasil: a experiência dos cursinhos populares

Pós-graduação em Ciências Sociais - FCLAR

A viola amplificada de Leo Canhoto e Robertinho: a trilha sonora do Brasil em transição

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A reivenção política do MST: uma análise do programa de reforma agrária do movimento dos trabalhadores rurais sem terra ao longo da sua história

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O reaproveitamento de notícias no jornalismo impresso contemporâneo: o caso do Caderno Diplô, do Le Monde Diplomatique Brasil

Pós-graduação em Comunicação - FAAC

Mangá: uma nova gênese : análise da história em quadrinhos Neon Genesis Evangelion

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A vocação auto-reflexiva da antropologia no Brasil: um retrato de sua historiografia a partir da década de oitenta

Pós-graduação em Ciências Sociais - FFC

Consórcio de exportação e a internacionalização das pequenas e médias empresas segundo a experiência italiana: um modelo para o Brasil. -

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)