Fiscal Update, April 10, 2006

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 18, 2006

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 5, 2007

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 12, 2007

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 18, 2007

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 26, 2007

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 8, 2008

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Fiscal Update, April 15, 2008

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

BAFF, APRIL and their receptors: structure, function and signaling.

BAFF, APRIL and their receptors play important immunological roles, especially in the B cell arm of the immune system. A number of splice isoforms have been described for both ligands and receptors in this subfamily, some of which are conserved between mouse and human, while others are species-specific. Structural and mutational analyses have revealed key determinants of receptor-ligand specificity. BAFF-R has a strong selectivity for BAFF; BCMA has a higher affinity for APRIL than for BAFF, while TACI binds both ligands equally well. The molecular signaling events downstream of BAFF-R, BCMA and TACI are still incompletely characterized. Survival appears to be mediated by upregulation of Bcl-2 family members through NF-kappaB activation, degradation of the pro-apototic Bim protein, and control of subcellular localization of PCKdelta. Very little is known about other signaling events associated with receptor engagement by BAFF and APRIL that lead for example to B cell activation or to CD40L-independent Ig switch.

1974 Survey of Dentists

This 1974 Survey of Dentists shows the number of dentists actively practicing in Iowa by county, age group, and type of practice.

Secure and Prepared Newsletter, April 19, 2007, Vol. 3, no. 6

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Secure and Prepared Newsletter, April 1, 2008, Vol. 4, no. 7

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Secure and Prepared Newsletter, April 24, 2008, Vol. 4, no. 8

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Secure and Prepared Newsletter, April 9, 2009, Vol. 5, no. 7

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management