Gottesdienstliche Vorträge gehalten im israelitischen Bethause zu Wien im Monate Tischri 5594

von I. N. Mannheimer

Mikraʾe ḳodesh oder Fest-Reden und Fest-Vorbereitungsreden für Israeliten, auf alle Feste des Jahres

gehalten und hrsg. von Salomon Plessner

Fest-Predigten

von Leopold Löwenstein. Hrsg. aus Anlass seines 25jäehrigen Bezirksjubiläums durch die dankbaren Gemeinden seines Rabbinats-Bezirks Mosbach, Merchingen, Wertheim

Die Offenbarung : Rede, gehalten am Wochenfeste 5651

von S. Gelbhaus

Der Kampf des Lebens : ein Cyclus von Festpredigten, in Beziehung zu dem grossen Völkerkampfe der Gegenwart, gehalten am Neujahr, Versöhnungstag & Freundenfest (5631-1870) im israelitischen Betsaale Westend-Union zu Frankfurt a. M

von Leopold Stein

Miḳraʾe ḳodesh oder Fest-Reden für Israeliten auf alle Feste des Jahres

von Salomon Plessner. Hrsg. von Elias Plessner

Zur Jahreswende : sieben Predigten zum Schlusse des Jahres 5654 und zum Beginne des Jahres 5655, in der Synagoge zu Lübeck

gehalten von S. Carlebach

Reden gehalten am Neujahrsfeste und Versöhnungstage des Jahres 1893 in Frankfurt am Main

von Adolf Brüll

In stiller Stunde : Betrachtungen über das Neujahrsfest und den Versöhnungstag, zur Stärkung der religiösen Gesinnung

verfasst und herausgegeben von M. Lewinger

Festpredigten für alle Feiertage des Herrn : gehalten im neuen Israelitischen Tempel zu Hamburg

von Gotthold Salomon

Die Feste des Herrn : israelitische Predigten für alle Festtage des Jahres, gehalten in dem neuen Tempel zu Hamburg

von E. Kley

Predigten zu den hohen Feiertagen gehalten in der Synagoge zu Offenbach a. M.

von Max Dienemann

Geschichte des Volkes Israel und der Entstehung des Christenthums

von Georg Weber und Heinr. Holtzmann

Childhood cancer survivor satisfaction with characteristics of clinical care

This study investigated the characteristics of a clinic that affect how satisfied survivors of childhood cancer are with their medical care. Questionnaire and interview data from the Passport for Care: Texas Implementation project collected between January 2011 to April 2012 were analyzed. Eleven clinics in Texas participated. Questionnaire respondents were childhood cancer survivor patients who had been off therapy for at least 2 years, or their parents. Interview respondents were clinical providers or research staff at the participating clinics. The outcomes evaluated were answers to a single question on satisfaction with care and a composite Percent Satisfaction Score created from seven other questionnaire items that were correlated (Spearman Rho >0.3) with the question on satisfaction. The following characteristics were also evaluated: sex, age, race, education, and type of cancer. The following clinic indicators were evaluated: type of clinic (general vs. dedicated cancer survivor clinics), number of providers, number of survivors, ratio of survivors/providers, distribution of handouts, distribution of treatment summaries, and use of Children's Oncology Group (COG) guidelines. ^ The only demographic characteristic that affected satisfaction was race. A Kruskal-Wallis test showed a statistically significant difference (Chi-square 6.129, 2 d.f., p = 0.0467). To analyze this further, Wilcoxon Rank Sum test of pairings of the three groups were performed. A Bonferroni correction for multiple testing was applied, with p = 0.017 indicating significance at alpha = 0.05. There was no significant difference between the White and Hispanic groups or between the Hispanic and "Other" groups. For the White and "Other" groups there was a significant difference for the satisfaction item (p = 0.0123) but not for the Percent Satisfaction Score (p = 0.0289). These results suggest that race may influence satisfaction and should be evaluated further in future studies. ^ None of the clinic indicators affected the Percent Satisfaction Score. Going to a clinic that distributed patient information handouts (Wilcoxon Rank Sum p = 0.048) and going to a clinic with >=100 survivors (Wilcoxon Rank Sum p = 0.021) were associated with increased satisfaction. The population of childhood cancer survivors is a growing group of individuals with special health needs. In the future survivors will likely seek medical care in a variety of clinical settings, so it is important to investigate features to improve patient satisfaction with clinical care.^

ATXA -dependent gene expression in Bacillus anthracis

The Bacillus anthracis toxin genes, cya, lef , and pag, can be viewed as a regulon, in which transcription of all three genes is activated in trans by the same regulatory gene, atxA, in response to the same signal, CO2. I determined that several phenotypes are associated with the atxA gene. In addition to being toxin-deficient, an atxA -null mutant grows poorly on minimal media and sporulates early compared to the parent strain. Furthermore, an atxA-null mutant has an altered 2-D gel protein profile. I used a genetic approach to find additional atxA-regulated genes. Random transcriptional lacZ fusions were generated in B. anthracis using transposon Tn 917-LTV3. Transposon-insertion libraries were screened for mutants expressing increased β-galactosidase activity in 5% CO2. Introduction of an atxA-null mutation in these mutants revealed that 79% of the CO2-regulated fusions were also atxA-dependent. DNA sequence analysis of transposon insertion sites in mutants carrying CO 2/atxA-regulated fusions revealed ten mutants harboring transposon insertions in loci distinct from the toxin genes. The majority of the tcr (toxin co-regulated) loci mapped within the pXO1 pathogenicity island. These results indicate a clear association of atxA with CO2-enhanced gene expression in B. anthracis and provide evidence that atxA regulates genes other than the structural genes for the anthrax toxin proteins. ^ Characterization of one tcr locus revealed a new regulatory gene, pagR. The pagR gene (300 nt) is located downstream of pag. pagR is cotranscribed with pag and is responsible for autogenous control of the operon. pagR also represses expression of cya and lef. Repression of toxin gene expression by pagR may be mediated by atxA. The steady state level of atxA mRNA is increased in a pagR mutant. Recombinant PagR protein purified from Escherichia coli did not specifically bind the promoter regions of pagA or atxA. An unidentified factor in B. anthracis crude extracts, however, was able to bind the atxA promoter in the absence of PagR or AtxA. These investigations increase our knowledge of virulence regulation in B. anthracis and ultimately will lead to a better understanding of anthrax disease. ^