1.° Ars judiciaria secundùm novem Judices : authore anonymo. — 2.° Anonymi liber de inundatione Nili. — 3.° Anonymi liber de coloribus. — 4.° Anonymi liber de bona fortuna. — 5.° Anonymi libellus de lineis invisibilibus. — 6.° Liber de morte Aristotelis. — 7.° Liber de intelligentia Aristotelis. — 8.° Liber de causa motûs animalium. — 9.° Liber de juventute et senectute. — 10.° Liber de respiratione. — 11.° Aristotelis liber de morte et vita.

Colbertinus

1.° Anonymi tractatus de algorismo, sive de arte numerandi : praemittuntur tractatus de numerorum mysteriis, et narratio Fratris Benedicti Aretini de indulgentia loco de Portiuncula concessa ab Honorio Papa III. — 2.° Magistri Joannis de Sacrobosco tractatus de computo. — 3.° Ejusdem tractatus de sphaera. — 4.° Theorica planetarum : authore Gerardo Carmonensi. — 5.° Anonymi explicationes allegoricae quorumdam Scripturae sacrae locorum : initium desideratur. — 6.° Elementorum Euclidis libri quinque priores. — 7.° Anonymi tractatus de speculis.

Colbertinus

1.° Waztalkora, sive tractatus de utilitatibus astrolabii. — 2.° Tractatus de horologio secundùm Alchoram, id est, sphaeram rotundam ; inprimìs de horis diei. — 3.° Evangelium sancti Matthaei, cum glossis. — 4.° Anonymi quaestiones physicae. — 5.° Isidori Hispalensis etymologiarum fragmenta : praemittuntur ejusdem epistolae ad Braulionem, cum hujus responsis. — 6.° Sancti Bernardi, Abbatis Claraevallensis, epistola ad Innocentium Papam, contra Petrum Abailardum. — Hujusce codicis pars duodecimo, pars decimo tertio saeculo videtur exarata.

nuper comparatus

1.° Sextus Pompeius Festus de verborum significatione. — 2.° Anonymi tractatus de rhetorica et de dialectica. — 3.° Aristotelis epistola ad Alexandrum de secretis secretorum. — 4.° Senecae liber ad Galeotum de vita beata. — 5.° Oeconomicorum Aristotelis liber : interprete Leonardo Aretino. — 6.° Isidori, Hispalensis, synonyma. — 7.° Messalae Corvini ad Octavium Augustum de progenie sua breve compendium.

Colbertinus

1.° M. T. Ciceronis rhetoricorum ad Herennium libri quatuor. — 2.° Joannis Boni Andreae, civis Bononiensis, ars dictaminis. — 3.° Joannis Candidi, Secretarii Imperialis, liber artis novae epistolarum. — 4.° Forma appellationis Raymundi de Oppeda, Sistarciensis Episcopi. — 5.° Ars memoriae secundùm Aristotelem et S. Thomam de Aquino. — 6.° Tractatus de baculo Jacob : authore anonymo. — 7.° Exordia secundùm Cassiodorum, de pace facienda inter Imperatorem et Regem. — 8.° Petri Blesensis epistolae nonnullae. — 9.° Guidonis de Columna historiae Trojanae libri decem priores.

Colbertinus

4

Although it has long been known that genetic factors play a major role in shaping the electroencephalogram (EEG), progress on identifying the underlying genes has, until recently, been limited. Using quantitative trait loci (QTL) analyses several genomic loci affecting the sleep EEG could be mapped in the mouse. For three of these QTLs the responsible genes were identified leading to the implication of novel signaling pathways affecting EEG traits. Moreover, the insight that in the mouse the sleep-wake dependent dynamics in the expression of EEG slow waves during sleep is under strong genetic control has paved the way for candidate gene studies in humans investigating the contribution of specific polymorphism to the trait-like inter-individual differences in the susceptibility to sleep loss. Candidate gene studies in the mouse were also instrumental in establishing an alternative, noncircadian function for clock genes in the homeostatic regulation of sleep and modulating rhythmic EEG activity of thalamocortical origin. Future efforts should combine system genetics approaches in the mouse and genome-wide association studies in humans to facilitate uncovering the molecular pathways that shape brain activity.

Dengue virus type 4 in Niterói, Rio de Janeiro: the role of molecular techniques in laboratory diagnosis and entomological surveillance

In Niterói, state of Rio de Janeiro, dengue virus type 4 (DENV-4) was isolated for the first time in March 2011. We analysed the laboratory findings of the first cases and evaluated the use of molecular techniques for the detection of DENV-4 in Aedes aegypti that were field-caught. Conventional reverse transcriptase-polymerase chain reaction (RT-PCR) and SimplexaTM Dengue real-time RT-PCR confirmed DENV-4 infection in all cases. Additionally, DENV-4 was confirmed in a female Ae. aegypti with 1.08 x 10³ copies/mL of virus, as determined by quantitative real-time RT-PCR. This is the first time the SimplexaTM Dengue real-time assay has been used for the classification of cases of infection and for entomological investigations. The use of these molecular techniques was shown to be important for the surveillance of dengue in humans and vectors.