External validation of the ASTRAL score to predict 3- and 12-month functional outcome in the China National Stroke Registry.

BACKGROUND AND PURPOSE: The ASTRAL score was recently introduced as a prognostic tool for acute ischemic stroke. It predicts 3-month outcome reliably in both the derivation and the validation European cohorts. We aimed to validate the ASTRAL score in a Chinese stroke population and moreover to explore its prognostic value to predict 12-month outcome. METHODS: We applied the ASTRAL score to acute ischemic stroke patients admitted to 132 study sites of the China National Stroke Registry. Unfavorable outcome was assessed as a modified Rankin Scale score >2 at 3 and 12 months. Areas under the curve were calculated to quantify the prognostic value. Calibration was assessed by comparing predicted and observed probability of unfavorable outcome using Pearson correlation coefficient. RESULTS: Among 3755 patients, 1473 (39.7%) had 3-month unfavorable outcome. Areas under the curve for 3 and 12 months were 0.82 and 0.81, respectively. There was high correlation between observed and expected probability of unfavorable 3- and 12-month outcome (Pearson correlation coefficient: 0.964 and 0.963, respectively). CONCLUSIONS: ASTRAL score is a reliable tool to predict unfavorable outcome at 3 and 12 months after acute ischemic stroke in the Chinese population. It is a useful tool that can be readily applied in clinical practice to risk-stratify acute stroke patients.

Les Comptes régionaux des branches industrielles en 1978 / Institut national de la statistique et des études économiques ; [par] Laurent Bisault

Collection : Les Collections de l'INSEE ; 426, 51

Les Comptes régionaux des branches industrielles en 1979 et 1980 / Institut national de la statistique et des études économiques ; [par] Laurent Bisault et Jean-Paul Blandinières

Collection : Les Collections de L'INSEE ; 454, 54

Comptes régionaux des branches industrielles de 1981 à 1983 / Ministère de l'économie, des finances et de la privatisation, Institut national de la statistique et des études économiques ; [réd. par] J.-C. Donnellier, J. Maliverney et E. Montlouis

Collection : Les Collections de l'INSEE ; 539, 63

L'Appareil productif régional de 1975 à 1984 : une analyse des valeurs ajoutées / Ministère de l'économie, des finances et de la privatisation, Institut national de la statistique et des études économiques ; [réd. par] Jean-Christophe Donnellier, Jacques Maliverney et Elisabeth Montlouis

Collection : Les Collections de l'INSEE ; 561, 64

Les Comptes régionaux des ménages 1981-1984 ; Les comptes régionaux des administrations publiques locales en 1982 / Institut national de la statistique et des études économiques ; [par] Jean-Christophe Donnellier [et] Patrick Blanc

Collection : Les Collections de l'INSEE ; 575, 67

Les Comptes régionaux des collectivités locales de 1962 à 1967 / Institut national de la statistique et des études économiques ; [rédigé] par Monique Gombert, Gérard Lattès et Jean-Claude Prager

Collection : Les Collections de l'Insee ; 80, 10

Les Comptes régionaux de l'agriculture : de 1962 à 1967 / Institut national de la statistique et des études économiques ; [rédigé] par Jean Ousset

Collection : Les Collections de l'Insee ; 104, 13

L'Adéquation entre la formation et l'emploi dans les régions / Ministère de l'économie et des finances, Institut national de la statistique et des études économiques ; [rédigé par] Jean-Marie Chanut

Collection : Les Collections de l'Insee ; 236, 26

Systematic review of evidence and consensus on diverticulitis: an analysis of national and international guidelines.

AIM: The study aimed to analyse the currently available national and international guidelines for areas of consensus and contrasting recommendations in the treatment of diverticulitis and thereby to design questions for future research. METHOD: MEDLINE, EMBASE and PubMed were systematically searched for guidelines on diverticular disease and diverticulitis. Inclusion was confined to papers in English and those < 10 years old. The included topics were classified as consensus or controversy between guidelines, and the highest level of evidence was scored as sufficient (Oxford Centre of Evidence-Based Medicine Level of Evidence of 3a or higher) or insufficient. RESULTS: Six guidelines were included and all topics with recommendations were compared. Overall, in 13 topics consensus was reached and 10 topics were regarded as controversial. In five topics, consensus was reached without sufficient evidence and in three topics there was no evidence and no consensus. Clinical staging, the need for intraluminal imaging, dietary restriction, duration of antibiotic treatment, the protocol for abscess treatment, the need for elective surgery in subgroups of patients, the need for surgery after abscess treatment and the level of the proximal resection margin all lack consensus or evidence. CONCLUSION: Evidence on the diagnosis and treatment of diverticular disease and diverticulitis ranged from nonexistent to strong, regardless of consensus. The most relevant research questions were identified and proposed as topics for future research.