Prognóstico de falhas baseado em redes neurais com estados de eco

Tese (mestrado)—Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia Mecânica, 2015.

Umberta Eco "dzieło otwarte" a Biblia

In this study the author presents the concept of the Umberto Eco’s model of "open work". The question is: if this model can be applied to Bible. Umberto Eco argued that literary texts have many fields of meaning, that they are understood as open, internally dynamic and psychologically engaged fields. We can say the same about Bible. The model of "open works" is very useful in the research of relation between Bible and a reader of Saint text. The model of "open works" does not include verification function of the community and Tradition.

Eco-eficiencia: la propuesta empresarial para el desarrollo sostenible

Quiero en primer lugar agradecer la amable invitación del ICESI y Ascolfa a participar en la décima reunión de la Asociación de Facultades de Administración. El tema central de este encuentro,la "Eco-administración", tiene una relación directa con la preocupación central y el objeto de trabajo del Cecodes: facilitar a los empresarios y a las organizqciones colombianas la incorporación del desarrollo sostenible, es decir, la visión de largo plazo y la integración de elementos sociales y ambientales en las decisiones de sus negocios.

TRANSFORMATIONS OF TASK-DEPENDENT PLASTICITY FROM A1 TO HIGHER-ORDER AUDITORY CORTEX

Everyday, humans and animals navigate complex acoustic environments, where multiple sound sources overlap. Somehow, they effortlessly perform an acoustic scene analysis and extract relevant signals from background noise. Constant updating of the behavioral relevance of ambient sounds requires the representation and integration of incoming acoustical information with internal representations such as behavioral goals, expectations and memories of previous sound-meaning associations. Rapid plasticity of auditory representations may contribute to our ability to attend and focus on relevant sounds. In order to better understand how auditory representations are transformed in the brain to incorporate behavioral contextual information, we explored task-dependent plasticity in neural responses recorded at four levels of the auditory cortical processing hierarchy of ferrets: the primary auditory cortex (A1), two higher-order auditory areas (dorsal PEG and ventral-anterior PEG) and dorso-lateral frontal cortex. In one study we explored the laminar profile of rapid-task related plasticity in A1 and found that plasticity occurred at all depths, but was greatest in supragranular layers. This result suggests that rapid task-related plasticity in A1 derives primarily from intracortical modulation of neural selectivity. In two other studies we explored task-dependent plasticity in two higher-order areas of the ferret auditory cortex that may correspond to belt (secondary) and parabelt (tertiary) auditory areas. We found that representations of behaviorally-relevant sounds are progressively enhanced during performance of auditory tasks. These selective enhancement effects became progressively larger as you ascend the auditory cortical hierarchy. We also observed neuronal responses to non-auditory, task-related information (reward timing, expectations) in the parabelt area that were very similar to responses previously described in frontal cortex. These results suggests that auditory representations in the brain are transformed from the more veridical spectrotemporal information encoded in earlier auditory stages to a more abstract representation encoding sound behavioral meaning in higher-order auditory areas and dorso-lateral frontal cortex.

I. Quantal effects in biochemical cooperativity and a proposed mechanism for the differentiation of calcium signaling in synaptic plasticity. II. Evolutionary algorithms for the optimization of methods in computational chemistry

In Part 1 of this thesis, we propose that biochemical cooperativity is a fundamentally non-ideal process. We show quantal effects underlying biochemical cooperativity and highlight apparent ergodic breaking at small volumes. The apparent ergodic breaking manifests itself in a divergence of deterministic and stochastic models. We further predict that this divergence of deterministic and stochastic results is a failure of the deterministic methods rather than an issue of stochastic simulations.

Ergodic breaking at small volumes may allow these molecular complexes to function as switches to a greater degree than has previously been shown. We propose that this ergodic breaking is a phenomenon that the synapse might exploit to differentiate Ca$^{2+}$ signaling that would lead to either the strengthening or weakening of a synapse. Techniques such as lattice-based statistics and rule-based modeling are tools that allow us to directly confront this non-ideality. A natural next step to understanding the chemical physics that underlies these processes is to consider \textit{in silico} specifically atomistic simulation methods that might augment our modeling efforts.

In the second part of this thesis, we use evolutionary algorithms to optimize \textit{in silico} methods that might be used to describe biochemical processes at the subcellular and molecular levels. While we have applied evolutionary algorithms to several methods, this thesis will focus on the optimization of charge equilibration methods. Accurate charges are essential to understanding the electrostatic interactions that are involved in ligand binding, as frequently discussed in the first part of this thesis.

Influence of Acute and Chronic Exercise on Markers of Hippocampal Plasticity

Exercise and physical activity are lifestyle behaviors associated with enriched mental health. Understanding the mechanisms by which exercise and physical activity improve mental health may provide insight for novel therapeutic approaches for numerous mental health disorders. This dissertation reports the findings from three studies investigating the influence of acute and chronic exercise on behavioral and mechanistic markers of hippocampal plasticity and delves into the potential role of noradrenergic signaling in the hippocampal adaptations with exercise. The first study assessed the effects of long-term voluntary wheel running on hippocampal expression of plasticity-associated genes and proteins in adult male and female C57BL/6J mice, highlighting sex differences in the adaptations to long-term voluntary wheel running. The second study examined the influence of acute exercise intensity on AMPA receptor phosphorylation, a mechanism essential for hippocampal plasticity, plasticity- associated gene expression, spatial learning and memory, and anxiety-like behavior. The unexpected finding that acute exercise increased anxiety-like behavior encouraged investigation into the role of central noradrenergic signaling in acute exercise-induced anxiety. The third study determined how previous exposure to voluntary wheel running modulates the response to an acute bout of exercise, focusing primarily on transcription of the important plasticity-promoting gene, brain-derived neurotrophic factor. Using a pharmacological approach to compromise the locus coeruleus noradrenergic system, a system that is implicated in age-related mental health disorders such as Alzheimer’s Disease, the third study also investigated the influence and interaction of the noradrenergic system and acute exercise on expression of multiple brain-derived neurotrophic factor transcripts. Together, this dissertation reports the findings from a series of experiments that explored similarities, differences, and interactions between the effects of acute and chronic exercise on markers of hippocampal plasticity and behavior. Further, this work provides insight into the role of the noradrenergic system in exercise-induced hippocampal plasticity.

Eco habitar Odivelas

Dissertação de Mestrado para a obtenção do grau de Mestre em Arquitectura, apresentada na Faculdade de Arquitectura da Universidade Técnica de Lisboa.

Diseño de un programa de comunicación de marketing integral, para generar demanda de los servicios eco-agroturístico ofertados por el hostal y restaurante lempa mar, ubicado en comunidad la pita, municipio de Tecoluca, departamento de San Vicente.

El Grupo Bajo Lempa, fue creado después de la firma de los acuerdos de paz, gracias a la cooperación de CORDES (Asociación para la Cooperación y el Desarrollo Comunal de El Salvador), el grupo está conformado por 50 comunidades en la costa del Océano Pacífico entre los departamentos de La Paz y San Vicente. Precisamente en éste último está ubicado el municipio de Tecoluca, ahí se encuentra ubicada la comunidad La Pita, comunidad que antes de los acuerdo de paz sus historias no eran más que de tristeza y mucho sacrificio. La Asociación Lempa Mar, surge del Grupo Bajo Lempa, con la iniciativa de aprovechar el potencial turístico de la zona; pero es hasta el año 2001, que comienzan a gestionarse proyectos para la construcción de cabañas que servirían de alojamiento y la búsqueda de un lugar que serviría para la construcción de un restaurante, esto dió paso al surgimiento del Hostal y Restaurante Lempa Mar. En la actualidad el Hostal y Restaurante Lempa Mar, recibe unos 200 visitantes por mes a los cuales se le ofrecen servicios de alojamiento y alimentación, así como actividades relacionadas con el eco-agroturismo. Sin embargo a pesar del trabajo realizado en estos años no se ha concretado un plan encaminado, a la captación de nuevos visitantes, por lo que la demanda de los servicios que se ofrecen es muy irregular, por esta razón se ha propuesto un Programa de Comunicación de Marketing Integral, para generar demanda de los servicios que allí se ofrecen. Para realizar la investigación se utilizó el método científico específicamente el método descriptivo, ya que su propósito es describir situaciones y variables para explicar cómo se manifiesta el fenómeno de interés. Para la recolección de datos se utilizaron encuestas, entrevistas así como también la observación directa, una vez recolectada la información se procedió al análisis de los datos, obteniendo así las fortalezas, oportunidades, debilidades y amenazas a las cuales se enfrenta el Hostal. A través del diagnóstico realizado se determinaron las causas que provocan la falta de demanda, tales como la falta de un adecuado plan de promoción, la explotación inadecuada de los recursos naturales de la zona; otro aspecto es la falta de utilización de publicidad no pagada. En función de los resultados de la investigación se diseñó un Programa de Comunicación de Marketing integral, que propone el desarrollo de estrategias creativas a corto plazo, que conlleven a lograr un posicionamiento y una ventaja diferencial. Finalmente se establece la forma de implementación, evaluación y control del programa.

Reabilitação eco-sustentável do património dos faróis

Dissertação para obtenção do grau de Mestre em Arquitectura, apresentada na Universidade de Lisboa - Faculdade de Arquitectura.

Viver em espaços pequenos, pré-fabricados e eco-sustentáveis

Dissertação para obtenção do grau de Mestre em Arquitectura com Especialização em Arquitectura, apresentada na Universidade de Lisboa - Faculdade de Arquitectura.

Parque agroindustrial eco-cota

Bogotá (Colombia): Universidad de La Salle. Facultad de Ciencias del Hábitat. Programa de Arquitectura

Molecularidad eco-agrícola en pro del desarrollo comunitario

Bogotá (Colombia): Universidad de La Salle. Facultad de Ciencias del Hábitat. Programa de Arquitectura

El eco de otra Alina. Intertextualidades en «Lejana» de Julio Cortazar

Se aborda el asunto de la intertextualidad y las voces de otras literaturas, desde Las mil y una noches hasta «La Cenicienta» en el cuento «Lejana» de Julio Cortázar.

Plasticity in leaf-level water relations of tropical rainforest trees in response to experimental drought.

The tropics are predicted to become warmer and drier, and understanding the sensitivity of tree species to drought is important for characterizing the risk to forests of climate change. This study makes use of a long-term drought experiment in the Amazon rainforest to evaluate the role of leaf-level water relations, leaf anatomy and their plasticity in response to drought in six tree genera. The variables (osmotic potential at full turgor, turgor loss point, capacitance, elastic modulus, relative water content and saturated water content) were compared between seasons and between plots (control and through-fall exclusion) enabling a comparison between short- and long-term plasticity in traits. Leaf anatomical traits were correlated with water relation parameters to determine whether water relations differed among tissues. The key findings were: osmotic adjustment occurred in response to the long-term drought treatment; species resistant to drought stress showed less osmotic adjustment than drought-sensitive species; and water relation traits were correlated with tissue properties, especially the thickness of the abaxial epidermis and the spongy mesophyll. These findings demonstrate that cell-level water relation traits can acclimate to long-term water stress, and highlight the limitations of extrapolating the results of short-term studies to temporal scales associated with climate change.

Objetivo fundamental de la universidad sostenible; educar al eco-ciudadano

Resumen No se puede hablar de desarrollo sostenible, si por desarrollo se entiende el modelo actualmente imperante en la sociedad de consumo del siglo  XXI. Para que sea sostenible se necesita situar esta sostenibilidad en un modelo ecológico de desarrollo humano. ¿En qué consiste este último tipo de desarrollo?¿En qué cosmovisión se soporta? Es la primera pregunta que se pretende contestar en el presente artículo. Para ello nos fijamos en siete puntos: quiénes son los autores que han contribuido al nacimiento del nuevo pensamiento; por qué es necesaria otra metanarrativa; qué cosmovisiones se han sucedido en la historia; cuál es la finalidad de la cosmovisión ecológica y de la moderna; principios fundamentales de ambas cosmologías; cuáles son las raíces físicas y astrofísicas de la cosmovisión ecológica y de la mecanicista o clásica; y qué consecuencias filosóficas se derivan de esos referentes.