Executive Order Number Forty Two, July 1991

Invokes across-the-board budget reductions as determinded by the Governor.

Executive Order Number Forty Three, April 30, 1992

Invokes further budget cuts as determinded by the Governor.

Executive Order Number Forty Four, April 30, 1992

Rescinds Executive Order #46 and recommits efforts of the Executive branch and all department directors, member of governing boards and commissions, and other public officers affirmative action, discriminatory harrassment prevention, and cultural diversity.

Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning.

DP1, a dimerization partner protein of the transcription factor E2F, is known to inhibit Wnt/β-catenin signalling along with E2F, although the function of DP1 itself was not well characterized. Here, we present a novel dual regulatory mechanism of Wnt/β-catenin signalling by DP1 independent from E2F. DP1 negatively regulates Wnt/β-catenin signalling by inhibiting Dvl-Axin interaction and by enhancing poly-ubiquitination of β-catenin. In contrast, DP1 positively modulates the signalling upon Wnt stimulation, via increasing cytosolic β-catenin and antagonizing the kinase activity of NLK. In Xenopus embryos, DP1 exerts both positive and negative roles in Wnt/β-catenin signalling during anteroposterior neural patterning. From subcellular localization analyses, we suggest that the dual roles of DP1 in Wnt/β-catenin signalling are endowed by differential nucleocytoplasmic localizations. We propose that these dual functions of DP1 can promote and stabilize biphasic Wnt-on and Wnt-off states in response to a gradual gradient of Wnt/β-catenin signalling to determine differential cell fates.

Executive Order Number Forty Five, August 27, 1992

Orders the Department of Econmic Development to work with the Regional Coordinating Council.

Executive Order Number Forty Six, January 5, 1993

Establish the TIM Council (Telecommunication and Informational Management)

Executive Order Number Forty Seven, March 29, 1993

Accepts offer of assignment of concurrent jurisdiction.

Executive Order Number Forty Eight, February 1994

Establish the Iowa Commission for National and Community Service

Executive Order Number Forty Nine, March 4, 1994

Establish the Telemedicine Advisory Council.

Executive Order Number Fifty, May 2, 1994

Establishs the Iowa Health Reform Transition Team. Rescinded by Executive Order #60.

Executive Order Number Sixty Eight, November 23, 1998

Prohabits use of all tobacco products in the areas of buildings under Governor's control in the State Capital Complex and all offices occupied by state government.

Executive Order Number Fifty Two, July 1, 1994

Replaces and rescinds Executive Order #35.

Executive Order Number Fifty Three, July 29, 1994

Eastablish an Iowa Workforce Development Council.

Executive Order Number Fifty Four, December 23, 1994

Replaces and rescinds Iowa Workforce Executive Order #39. Rescinded by Exectuive Order #62.

Executive Order Number Fifty Five, June 22, 1995

Appoints the Des Moines resident-in-charge for the U.S. Drug Enforcement Adminstration as a nonvoting ex-officio member of the Iowa Law Enforcement Academy Council.