Innovación educativa en las redes sociales online: un estudio en la educación superior

Las redes sociales son tan antiguas como las relaciones entre los humanos, ya que las labores de cooperación siempre fueron imprescindibles en los procesos de asociación, tanto los formados por simples células hasta los constituidos por seres vivos. La sociedad está formada por una gran cantidad de situaciones que fomentan dicha colaboración. Desde la creación del Espacio Europeo de Educación Superior se ha promovido la utilización de entornos virtuales de aprendizaje que favorezcan una evaluación más transparente y objetiva. Las redes sociales online son las interfaces digitales más utilizadas por los estudiantes universitarios, por lo que son muchos los expertos que recomiendan analizar la utilidad educativa de este tipo de aplicaciones. Siguiendo estas recomendaciones se implementó una red social online, llamada Formatio, que se utilizó para apoyar el proceso de enseñanza y aprendizaje en la educación superior. El objetivo general de esta tesis doctoral fue valorar el nivel de aceptación de este entorno virtual de aprendizaje para los estudiantes universitarios que participaron en este estudio. Para evaluar el uso de la plataforma se analizaron las actividades generadas por los 172 estudiantes, seleccionados aleatoriamente, matriculados en la asignatura de Estadística y TIC en el curso 2010/2011, del Grado en Ciencias de la Actividad Física y el Deporte. Con el objetivo de estimar la utilidad educativa de las redes sociales online se diseñó y validó el instrumento de Valoración de Recursos Educativos Online (VREO), que fue aplicado a otra muestra aleatoria de 452 estudiantes de la misma facultad durante el curso 2011/2012. Los resultados confirman el éxito de este tipo de espacios virtuales gracias a la alta frecuencia de uso conseguida y a las buenas puntuaciones obtenidas por los alumnos, quienes tienen una buena opinión sobre las ventajas de usar las redes sociales online en la educación superior. De todos los recursos analizados la red social online Formatio ha sido la opción mejor valorada, seguida de Moodle y Facebook en segundo y tercer lugar, y de Twitter y YouTube, en cuarta y en quinta posición. Este estudio establece un punto de partida para futuras investigaciones encaminadas a obtener ciertos indicadores cualitativos y cuantitativos que faciliten una evaluación más justa de los actores integrantes de los sistemas educativos, que ayude a abrir las puertas de nuestra sociedad a la responsabilidad, la eficiencia, la transparencia y la objetividad. ABSTRACT Social networks are as old as human relations, since cooperative work has always been indispensable in all processes of association, from those composed of simple cells to those formed by living beings. Society is shaped by a large amount of situations that stimulate this cooperation. Since the creation of the European Higher Education Area, the use of virtual learning environments that favor more transparent and objective evaluation has been promoted. On-line social networks are the digital interfaces most widely used by university students, which is the reason why many experts recommend an analysis of the educational utility of this type of applications. Following these recommendations, an on-line social network called Formatio was created, which was used in order to support the teaching and learning process in higher education. The general objective of this doctoral dissertation was to evaluate the level of acceptance of this virtual learning environment by the university students who participated in this study. In order to evaluate the use of the platform, the activity created by 172 students chosen at random was analyzed; they were registered in the course on Statistics and Information and Communication Technology of the degree program in Sciences of Physical Activity and Sport during the academic year 2010/2011. With the goal of appraising the educational utility of on-line social networks, a tool for Evaluation of On-line Educational Resources (EOER) was designed, validated, and applied to another random sample of 452 students from the same department during the academic year 2011/2012. The results confirm the success of this type of virtual spaces, thanks to the high frequency of use achieved and the good grades obtained by the students who had a favorable opinion of the advantages of using on-line social networks in higher education. Out of all the resources analyzed, the Formatio on-line social network was the option that received the best evaluation, followed by Moodle and Facebook, which were second and third, and Twitter and YouTube, in fourth and fifth place respectively. This study establishes a starting point for future research that aims to obtain certain qualitative and quantitative indicators that will make it easier to engage in a fairer evaluation of the parties involved in education systems, which will help open the doors of our society to responsibility, efficiency, transparency, and objectivity.

Feasibility and utility of population-level geospatial injury profiling : prospective, national cohort study

The Health Services Research Unit receives funding from the Chief Scientist Office of the Scottish Government Health and Social Care Directorates. The opinions expressed in this article are those of the authors alone. The GEOS study was funded by the North of Scotland Planning Group.

Multistability, chaos, and random signal generation in semiconductor superlattices

Peer reviewed

Broken symmetry and critical transport properties of random metals

Recent experimental data on the conductivity σ+(T), T → 0, on the metallic side of the metal–insulator transition in ideally random (neutron transmutation-doped) 70Ge:Ga have shown that σ+(0) ∝ (N − Nc)μ with μ = ½, confirming earlier ultra-low-temperature results for Si:P. This value is inconsistent with theoretical predictions based on diffusive classical scaling models, but it can be understood by a quantum-directed percolative filamentary amplitude model in which electronic basis states exist which have a well-defined momentum parallel but not normal to the applied electric field. The model, which is based on a new kind of broken symmetry, also explains the anomalous sign reversal of the derivative of the temperature dependence in the critical regime.

Critical transport properties of random metals in large magnetic fields

The threshold behavior of the transport properties of a random metal in the critical region near a metal–insulator transition is strongly affected by the measuring electromagnetic fields. In spite of the randomness, the electrical conductivity exhibits striking phase-coherent effects due to broken symmetry, which greatly sharpen the transition compared with the predictions of effective medium theories, as previously explained for electrical conductivities. Here broken symmetry explains the sign reversal of the T → 0 magnetoconductance of the metal–insulator transition in Si(B,P), also previously not understood by effective medium theories. Finally, the symmetry-breaking features of quantum percolation theory explain the unexpectedly very small electrical conductivity temperature exponent α = 0.22(2) recently observed in Ni(S,Se)2 alloys at the antiferromagnetic metal–insulator transition below T = 0.8 K.

Random locomotion and chemotaxis of human blood polymorphonuclear leukocytes (PMN) in the presence of EDTA: PMN in close quarters require neither leukocyte integrins nor external divalent cations

Divalent cations are thought essential for motile function of leukocytes in general, and for the function of critical adhesion molecules in particular. In the current study, under direct microscopic observation with concomitant time-lapse video recording, we examined the effects of 10 mM EDTA on locomotion of human blood polymorphonuclear leukocytes (PMN). In very thin slide preparations, EDTA did not impair either random locomotion or chemotaxis; motile behavior appeared to benefit from the close approximation of slide and coverslip (“chimneying”). In preparations twice as thick, PMN in EDTA first exhibited active deformability with little or no displacement, then rounded up and became motionless. However, on creation of a chemotactic gradient, the same cells were able to orient and make their way to the target, often, however, losing momentarily their purchase on the substrate. In either of these preparations without EDTA, specific antibodies to β2 integrins did not prevent random locomotion or chemotaxis, even when we added antibodies to β1 and αvβ3 integrins and to integrin-associated protein, and none of these antibodies added anything to the effects of EDTA. In the more turbulent environment of even more media, effects of anti-β2 integrins became evident: PMN still could locomote but adhered to substrate largely by their uropods and by uropod-associated filaments. We relate these findings to the reported independence from integrins of PMN in certain experimental and disease states. Moreover, we suggest that PMN locomotion in close quarters is not only integrin-independent, but independent of external divalent cations as well.

Identification of fission yeast nuclear markers using random polypeptide fusions with green fluorescent protein

We describe a method for identifying genes encoding proteins with stereospecific intracellular localizations in the fission yeast Schizosaccharomyces pombe. Yeast are transformed with a gene library in which S. pombe genomic sequences are fused to the gene encoding the Aequorea victoria green fluorescent protein (GFP), and intracellular localizations are subsequently identified by rapid fluorescence screening in vivo. In a model application of these methods to the fission yeast nucleus, we have identified several novel genes whose products are found in specific nuclear regions, including chromatin, the nucleolus, and the mitotic spindle, and sequence similarities between some of these genes and previously identified genes encoding nuclear proteins have validated the approach. These methods will be useful in identifying additional components of the S. pombe nucleus, and further extensions of this approach should also be applicable to a more comprehensive identification of the elements of intracellular architecture in fission yeast.

Shape anisotropy of a single random-walk polymer

Random walks have been used to describe a wide variety of systems ranging from cell colonies to polymers. Sixty-five years ago, Kuhn [Kuhn, W. (1934) Kolloid-Z. 68, 2–11] made the prediction, backed later by computer simulations, that the overall shape of a random-walk polymer is aspherical, yet no experimental work has directly tested Kuhn's general idea and subsequent computer simulations. By using fluorescence microscopy, we monitored the conformation of individual, long, random-walk polymers (fluorescently labeled DNA molecules) at equilibrium. We found that a polymer most frequently adopts highly extended, nonfractal structures with a strongly anisotropic shape. The ensemble-average ratio of the lengths of the long and short axes of the best-fit ellipse of the polymer was much larger than unity.

Random allocation or allocation at random? Patients’ perspectives of participation in a randomised controlled trial

Objectives To explore trial participants’ understandings of randomisation.

Identification of two short internal ribosome entry sites selected from libraries of random oligonucleotides

Sequences that control translation of mRNA may play critical roles in regulating protein levels. One such element is the internal ribosome entry site (IRES). We previously showed that a 9-nt segment in the 5′ leader sequence of the mRNA encoding Gtx homeodomain protein could function as an IRES. To identify other short sequences with similar properties, we designed a selection procedure that uses a retroviral vector to express dicistronic mRNAs encoding enhanced green and cyan fluorescent proteins as the first and second cistrons, respectively. Expression of the second cistron was dependent upon the intercistronic sequences and was indicative of IRES activity. B104 cells were infected with two retroviral libraries that contained random sequences of 9 or 18 nt in the intercistronic region. Cells expressing both cistrons were sorted, and sequences recovered from selected cells were reassayed for IRES activity in a dual luciferase dicistronic mRNA. Two novel IRESes were identified by this procedure, and both contained segments with complementarity to 18S rRNA. When multiple copies of either segment were linked together, IRES activities were dramatically enhanced. Moreover, these synthetic IRESes were differentially active in various cell types. These properties are similar to those of the previously identified 9-nt IRES module from Gtx mRNA. These results provide further evidence that short nucleotide sequences can function as IRESes and support the idea that some cellular IRESes may be composed of shorter functional modules. The ability to identify IRES modules with specific expression properties may be useful in the design of vectors for biotechnology and gene therapy.

A genomic approach to gene fusion technology

Gene expression profiling provides powerful analyses of transcriptional responses to cellular perturbation. In contrast to DNA array-based methods, reporter gene technology has been underused for this application. Here we describe a genomewide, genome-registered collection of Escherichia coli bioluminescent reporter gene fusions. DNA sequences from plasmid-borne, random fusions of E. coli chromosomal DNA to a Photorhabdus luminescens luxCDABE reporter allowed precise mapping of each fusion. The utility of this collection covering about 30% of the transcriptional units was tested by analyzing individual fusions representative of heat shock, SOS, OxyR, SoxRS, and cya/crp stress-responsive regulons. Each fusion strain responded as anticipated to environmental conditions known to activate the corresponding regulatory circuit. Thus, the collection mirrors E. coli's transcriptional wiring diagram. This genomewide collection of gene fusions provides an independent test of results from other gene expression analyses. Accordingly, a DNA microarray-based analysis of mitomycin C-treated E. coli indicated elevated expression of expected and unanticipated genes. Selected luxCDABE fusions corresponding to these up-regulated genes were used to confirm or contradict the DNA microarray results. The power of partnering gene fusion and DNA microarray technology to discover promoters and define operons was demonstrated when data from both suggested that a cluster of 20 genes encoding production of type I extracellular polysaccharide in E. coli form a single operon.