Diseñó e implementación de un frameword de persistencia

L'objectiu d'aquest PFC és realitzar un estudi complet des de l'àmbit d'allò general (què és un framework), passant per l'anàlisi de les característiques dels framework, fins arribar al detall pel que fa als framework de persistència.

XifraXat : Xat segur

XifraXat és un sistema que permet a dos usuaris gaudir d'una conversa del tot privada. Assegura la privacitat als usuaris ja que utilitza un sistema de xifra Diffie-Hellman, que com tots els sistemas de xifra pública, el xifratge el fa l'usuari a partir de les seves claus.

Diseño y desarrollo de un cliente WPS en el entorno GVSIG

Extensió per gvSIG anomenada extWPS, que permet executar processos a través de Web Processing Service (wps), el protocol promogut per l'Open Geospatial Consortium (OGC). El programari, elaborat en Java, es basa en el conjunt de llibreries de la iniciativa 52north i té llicència GPL. Fa possible, una vegada instal lat sobre gvSIG, connectar-se a un servidor wps, veure els geoprocesos disponibles a ell i executar de manera remota.

Enzyme-linked immunosorbent assay and Western blot antibody determination in sera from patients diagnosed with different helminthic infections with Anisakis simplex antigen purified by affinity chromatography

An evaluation of the sensitivity and the specificity of the Anisakis simplex antigens purified by affinity chromatography was performed using sera from patients diagnosed with Anisakis sensitisation and sera from patients previously diagnosed with different helminthic infections. Only the sera of the patients diagnosed with Schistosoma mansoni or Onchocerca volvulus parasitic infections were negative against the A. simplex antigen and its purified fractions (PAK antigen: A. simplex antigen purified using columns prepared with anti-A. simplex rabbit IgG and PAS antigen: PAK antigen purified using columns prepared with anti-Ascaris suum rabbit IgG). However all the sera were positive against the A. suum antigen. In all the sera from the patients diagnosed with Anisakis sensitisation, the antibody levels detected using the purified antigens (PAK and PAS antigens) were lower than the observed using the A. simplex crude extract with the highest diminution in the case of the IgG. When these same sera were tested against the A. simplex crude extract by Western blot, several bands of high molecular masses were observed as well as, intense bands at 60 and/or 40 kDa. A concentration of these last proteins was observed in the PAK and the PAS antigens. When the sensitivity and the specificity determinations were performed, only seven of the 38 patients diagnosed of Anisakis sensitisation were positive, as well as, the sera from the patients diagnosed with parasitisms by Echinococcus granulosus or Fasciola hepatica.

Configuración de un equipo de proyecto informático eficiente

Aquest treball se circumscriu en l'àmbit de la gestió de projectes, una activitat que fa referència a l'òptima utilització dels recursos financers, materials i humans per tal de desenvolupar un treball determinat i únic sota un confinament temporal i econòmic precís.

RDF i Web Semàntica

En aquest treball s'explica el concepte de Web Semàntica, junt amb la seva estructura i els diferents termes relacionats amb aquesta idea. A més, es fa especial atenció al paper dels sistemes gestors de bases de dades en aquest camp, tenint en compte sobretot el nivell de compatibilitat que ofereixen aquests per a tracta dades en notació RDF, basada en el llenguatge XML.

Effects of antifolates - co-trimoxazole and pyrimethamine-sulfadoxine - on gametocytes in children with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria

Antimalarial drugs including the antifolate, pyrimethamine-sulfadoxine (PS), can modulate the prevalence and intensities of gametocytaemia following treatment of acute malaria infections. They may also directly influence the transmission and spread of drug insensitivity. Little is known of the effects of co-trimoxazole (Co-T), another antifolate antimalarial, on gametocytes in children with acute malaria infections. We compared the effects of Co-T and PS on the prevalence and intensities of gametocytaemia and gametocyte sex ratios in 102 children aged 0.5-12 years presenting with acute and uncomplicated falciparum malaria. Compared to pre-treatment, both drugs significantly increased gametocyte carriage post-initiation of treatment. However, gametocyte carriage was significantly lower on day 14 in those treated with Co-T than PS. Significant increase in gametocytaemia with time occurred in PS - but not Co-T-treated children. Kaplan-Meier survival curve of the cumulative probability of remaining gametocyte-free in children who were agametocytaemic at enrolment showed that by day 7 of follow up, children treated with PS had a significantly higher propensity to have developed gametocytes than in Co-T-treated children (Log-rank statistic 5.35, df = 1, P = 0.02). Gametocyte sex ratio changes were similar following treatment with both drugs. PS and Co-T treatment of acute malaria infections in children from this endemic area is associated with significant increases in prevalence and intensities of gametocytaemia but these effects are more marked in those treated with PS than Co-T.

Connectome alterations in schizophrenia

Introduction : DTI has proven to be an exquisite biomarker of tissue microstructure integrity. This technique has been successfully applied to schizophrenia in showing that fractional anisotropy (FA, a marker of white matter integrity) is diminished in several areas of the brain (Kyriakopoulos M et al (2008)). New ways of representing diffusion data emerged recently and achieved to create structural connectivity maps in healthy brains (Hagmann P et al. (2008)). These maps have the capacity to study alterations over the entire brain at the connection and network level. This is of high interest in complex disconnection diseases like schizophrenia. We report on the specific network alterations of schizophrenic patients. Methods : 13 patients with chronic schizophrenia were recruited from in-patient, day treatment, out-patient clinics. Comparison subjects were recruited and group-matched to patients on age, sex, handedness, and parental social economic-status. This study was approved by the local IRB and subjects had to give informed written consent. They were scanned with a 3T clinical MRI scanner. DTI and high-resolution anatomical T1w imaging were performed during the same session. The path from diffusion MRI to a multi-resolution structural connection matrices of the entire brain is a five steps process that was performed in a similar way as described in Hagmann P et al. (2008). (1) DTI and T1w MRI of the brain, (2) segmentation of white and gray matter, (3) white matter tractography, (4) segmentation of the cortex into 242 ROIs of equal surface area covering the entire cortex (Fig 1), (5) the connection network was constructed by measuring for each ROI to ROI connection the related average FA along the corresponding tract. Results : For every connection between 2 ROIs of the network we tested the hypothesis H0: "average FA along fiber pathway is larger or equal in patients than in controls". H0 was rejected for connections where average FA in a connection was significantly lower in patients than in controls. Threshold p-value was 0.01 corrected for multiple comparisons with false discovery rate. We identified consistently that temporal, occipito-temporal, precuneo-temporal as well as frontal inferior and precuneo-cingulate connections were altered (Fig 2: significant connections in yellow). This is in agreement with the known literature, which showed across several studies that FA is diminished in several areas of the brain. More precisely, abnormalities were reported in the prefrontal and temporal white matter and to some extent also in the parietal and occipital regions. The alterations reported in the literature specifically included the corpus callosum, the arcuate fasciculus and the cingulum bundle, which was the case here as well. In addition small world indexes are significantly reduced in patients (p<0.01) (Fig. 3). Conclusions : Using connectome mapping to characterize differences in structural connectivity between healthy and diseased subjects we were able to show widespread connectional alterations in schizophrenia patients and systematic small worldness decrease, which is a marker of network desorganization. More generally, we described a method that has the capacity to sensitively identify structure alterations in complex disconnection syndromes where lesions are widespread throughout the connectional network.

SENDCRYPT

Aplicació universal per qualsevol telèfon mòbil que compleixi uns mínims requisits que permeti a l'usuari enviar i rebre missatges SMS (Short Message Service) encriptats i així poder mantenir la privacitat d'aquests de la mateixa manera que ho fa un usuari de PGP (Pretty Good Privacy) o OpenPGP.

Usabilitat dels gestors de contingutscom a espai per a la relació-comunicació professor alumne dins la web d'un centre de secundària

Aquest treball fa una incursió en els Gestors de Continguts del mercat especialitzats en entorns educatius i es divideix en dues parts: En la primera es fa una comparativa entre els gestors de continguts Moodle, Atutor i Aula Wiki a través de la seva Avaluació Heurística basada en els principis de Jakob Nielsen.En la segona part, a partir del gestor de continguts que ha obtingut millor puntuació en la Avaluació Heurística, es realitza un Test d'Usuaris amb professors d'ensenyament secundari de diverses Àrees.

Bases de dades XML natives per gestionar documents MPEG-7

Aquest projecte estudia fonamentalment el llenguatge XML i l'ús que se'n fa com a mitjà per a compartir informació entre sistemes i aplicacions diferents, gràcies a la utilització del format text com a base de creació.

Esquema criptogràfic per a gestionar de forma segura els historials mèdics dels pacients a través d'una xarxa de comunicacions.

Aquest projecte forma part de l'àrea de seguretat informàtica. Fa una implementació d'un esquema criptogràfic per gestionar de forma segura els historials mèdics dels pacients a través d'una xarxa de comunicacions.

Analitzador del tràfic de Xarxa per entorn Linux 'Sniff All'

L'objectiu d'aquest treball de final de carrera és clar pel que fa a la funcionalitat: es tracta de fer un analitzador de xarxa (vulgarment conegut com a detector) que funcioni en entorns Linux i amb interfícies d'usuari gràfiques.

XML / XQuery Languages : estado del arte

Aquest treball fa un recull d'informació de l'estàndard XML i dels llenguatges de consultes XQuery, que són llenguatges de consultes dissenyats per a fer accessos a aquest tipus de dades.

Aplicació web per a la gestió de comandes amb J2EE

La present memòria descriu els passos necessaris per fer l'anàlisi, el disseny i la implementació de un gestor de comandes per un empresa mitjançant l'entorn web. El projecte ha estat realitzat en llenguatge Java, ja que és un llenguatge orientat a l'objecte molt reutilitzable i que té una plataforma que és la J2EE, que la fa ideal per l'unió de pàgines web amb bases de dades.