885 resultados para Optic neuropathy
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提出了一种新型的基于电光调制的激光光谱整形方案,该整形技术可以减轻啁啾脉冲放大系统中的增益窄化效应。傅立叶变换限的宽带种子激光脉冲通过光学展宽器线性展宽后,耦合到加载有整形电脉冲的集成波导调制器中进行整形,整形电脉冲由孔径耦合带状线电脉冲发生器产生。由于线性啁啾脉冲时间-频率的直接对应关系,在时域内对宽带种子激光脉冲整形,其光谱也得到了同样形状的整形。模拟了整形光谱形状,相应的整形电脉冲波形,分析了该整形技术的光谱整形分辨率,以及整形过程中引入的相位畸变。
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用数值方法研究了激光驱动器系统中使用光谱色散平滑单元后光束的衍射特性、模拟结果表明,光谱色散会使光束衍射光斑变大,近场空间强度均匀性改善,而远场光斑内部存在光强接近于均匀分布的区域.进一步分析了光谱色散平滑单元中相位调制器的调制深度、调制频率及光栅色散系数等主要元件参数对光束传输特性的影响,发现在一定情况下光斑内部会出现较强的强度调制。
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O diagnóstico precoce e o tratamento são imprescindíveis para o controle da hanseníase, pois visam eliminar o mais precocemente possível as fontes de transmissão. O principal critério de cura da doença é o tempo de tratamento, relacionado às doses fixas da poliquimioterapia. O tempo de tratamento dos pacientes multibacilares foi reduzido de 24 para 12 doses em até 18 meses em 1998. Os objetivos desta tese foram: avaliar a detecção de casos de hanseníase entre os contatos dos pacientes e avaliar fatores de risco associados à piora das incapacidades físicas nos pacientes após a alta do tratamento poliquimioterápico com as 12 doses mensais. Dois artigos foram elaborados. O primeiro artigo avaliou características dos pacientes com hanseníase e de seus contatos associadas ao risco de adoecimento entre os contatos. O segundo artigo avaliou fatores de risco relacionados à piora das incapacidades físicas dos pacientes com hanseníase multibacilar, submetidos ao tratamento com 12 doses fixas da poliquimioterapia. Os resultados mostraram que o risco para hanseníase, relacionado aos contatos foi o tipo de convivência com o caso índice. Entre os fatores dos casos índices, a carga bacilar foi o único associado ao adoecimento dos contatos. Além desses fatores, os contatos que apresentam relação de consangüinidade com o caso índice e os contatos dos pacientes com menor nível de escolaridade mostraram maior chance de se apresentarem doentes no momento do diagnóstico do caso índice. A cicatriz BGC e a vacina recebida após o diagnóstico do caso índice contribuíram independentemente como fatores de proteção. A neuropatia piorou em 40% dos pacientes durante o período de 10 anos após a alta do tratamento. Esta piora foi associada à presença de incapacidades físicas e ao número de lesões cutâneas no momento do diagnóstico assim como à presença de neurite durante o acompanhamento.
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Background: Type 2 diabetes mellitus is associated with a diverse range of pathologies. The aim of the study was to determine the incidence of diabetes-related complications, the prevalence of coexistent chronic conditions and to report multimorbidity in people with type 2 diabetes living in the Basque Country. Methods: Administrative databases, in four cross sections (annually from 2007 to 2011) were consulted to analyse 149,015 individual records from patients aged >= 35 years with type 2 diabetes mellitus. The data observed were: age, sex, diabetes-related complications (annual rates of acute myocardial infarction, major amputations and avoidable hospitalisations), diabetes-related pathologies (prevalence of ischaemic heart disease, renal failure, stroke, heart failure, peripheral neuropathy, foot ulcers and diabetic retinopathy) and other unrelated pathologies (44 diseases). Results: The annual incidence for each condition progressively decreased during the four-year period: acute myocardial infarction (0.47 to 0.40%), major amputations (0.10 to 0.08%), and avoidable hospitalisations (5.85 to 5.5%). The prevalence for diabetes-related chronic pathologies was: ischaemic heart disease (11.5%), renal failure (8.4%), stroke (7.0%), heart failure (4.3%), peripheral neuropathy (1.3%), foot ulcers (2.0%) and diabetic retinopathy (7.2%). The prevalence of multimorbidity was 90.4%. The highest prevalence for other chronic conditions was 73.7% for hypertension, 13.8% for dyspepsia and 12.7% for anxiety. Conclusions: In the type 2 diabetes mellitus population living in the Basque Country, incidence rates of diabetes complications are not as high as in other places. However, they present a high prevalence of diabetes related and unrelated diseases. Multimorbidity is very common in this group, and is a factor to be taken into account to ensure correct clinical management.
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报道了一种基于光时域反射计的全分布式光纤漏油传感器,该传感器能实现分布式实时监测长输油管道,及时发现小型的漏油事件.传感器沿管道铺设,利用光时域反射计实时测量光纤在长度上的损耗变化特点,及时发现并定位管道上的每一处泄漏事件.模拟实验证明了其实际操作的可行性,长期使用的稳定性和各种抗干扰性,能在15min内发现并定位漏油事件,且定位准确度为3m.
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采用面泵浦的CAMIL结构,我们研究了970 nm泵浦的Yb:YAG/YAG复合陶瓷薄片激光器,获得了连续和调Q的激光输出。在连续运转情况下,获得了最高1.05 W的激光输出,中心波长为1031 nm,后腔输出镜透射率为2%。我们同时获得了声光调Q的脉冲输出,重复频率从1 kHz到30 kHz,脉宽分别从166 ns到700 ns。
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报道了半导体激光器端面抽运不同结构的声光调Q的双包层光纤激光器的脉冲输出特性.对前向、后向不同抽运方式的掺镱调Q双包层光纤激光器在输出平均功率,调Q脉冲宽度及脉冲稳定性进行了对比及讨论;其中后向抽运的光纤激光器,在10kHz重复频率调制下,获得了斜效率为60%的平均功率输出,其脉冲宽度为52ns,单脉冲能量为0·3mJ.最后利用不同抽运方式下的速率方程,理论分析调Q脉冲的特性,分析结果与实验相符.
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报道了全固态激光器连续抽运高重复率电光调Q的实验和理论分析结果。用LGS(La3Ga5SiO14)晶体作电光调Q元件,在激光二极管(LD)端面抽运Nd:YVO4激光器中实现了较高重复率的电光调Q输出。实验中在10^4Hz重复率下,抽运功率为28w时,平均功率超过5W,脉冲宽度为7ns,峰值功率为70kW,并对不同重复率时的脉冲输出进行了比较,在低重复率下,脉宽〈6.5ns,峰值功率超过100kW。在理论上,通过对连续抽运时的电光调Q速率方程进行修正,并考虑放大自发辐射(ASE)的影响,对调Q激光器的储能过
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报道了利用声光振幅调制锁模的方法,在激光二极管端面抽运Nd:YVO4激光器上获得320MHz高重复频率脉冲列的实验结果。实验采用平一平腔结构,腔长452mm,耦合输出镜透过率为3.6%。所用声光介质为熔融石英晶体,以铌酸锂作换能器,在驱动功率4.5W时,对1064nm波长衍射效率为50,相应的调制深度为0.31。在最佳锁模状态下,激光二极管抽运功率为3.5W,此时激光平均输出功率为15mw。示波器记录脉冲宽度680ps,实测光束质量因子M^2小于1.5。并在实验基础上对激光器工作的稳定性进行了分析,结果表
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为了有效地补偿激光二极管(LD)侧向抽运1000 Hz重复率电光调Q Nd:YAG激光器棒状增益介质内存在的热致双折射损耗,设计了一种新颖的双调Q晶体开关复合谐振腔结构。实验结果表明,设计的双调Q晶体开关结构Nd:YAG激光器输出激光脉冲能量比单调Q晶体开关结构的非补偿腔输出能量提高了56%,当侧面抽运半导体激光器输出功率达到450 W时,激光输出达到30 mJ/pulse,输出光束偏振度优于10:1,激光脉冲宽度约14 ns。并获得6.7%的光-光转换效率。通过对双调Q开光激光谐振腔进行建模,并用求解速
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为了同时补偿固体增益介质的热致双折射及热透镜效应,进一步提高重复频率1 kHz激光二极管(LD)侧向抽运高平均功率电光调Q Nd:YAG激光器的输出功率,设计了一种完全消除热退偏损耗的双调Q开关谐振腔结构,此结构在传统调Q谐振腔的基础上沿着偏振片的退偏方向增加了一个调Q谐振支路,并使得激光从增益介质方向输出。实验结果表明,此激光器的单脉冲能量比单Q开关结构的非补偿腔输出能量高出74.7%。当侧面抽运的激光二极管输出脉冲能量达到307 mJ时,激光输出能量达到26.2 mJ,光-光转换效率为8.5%,光束发
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高重复频率、窄脉宽的全固态激光器种子源级联光纤放大器是获得高功率脉冲激光输出的有效手段.短上能态寿命的Nd∶YVO4晶体在连续抽运、高重复频率Q开关工作时容易得到接近连续性能的平均输出功率.理论分析了声光(AO)调Q器件中影响输出能量和脉宽大小的主要因素,优化配置了腔型参数.利用激光二极管(LD)光纤耦合模块端面抽运Nd∶YVO4晶体,实现了声-光调Q重复频率100 kHz以上,脉宽20 ns以下,波长1064 nm的激光输出.在抽运功率5.7 W时,得到了脉宽15.3 ns,重复频率150 kHz的种子光输出,在级联单级光纤放大器后,得到了20 W的输出.
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实验报道采用我国自行设计的大模场掺镱双包层光纤,利用简单声光调Q装置,成功实现调Q运转;在1-50kHz调制频率下获得了百纳秒的调Q脉冲,其输出光束质量因子大约为2。当重复频率为1kHz时,获得了脉冲宽度为132ns,能量0.93mJ。同时实验中观察到的调Q脉冲常出现一点锁模现象,针对这一现象进行了讨论。
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根据激光多普勒测振技术进行声光通信的工作原理,设计一种新型、小型激光多普勒测振信号鉴频电路。该电路根据外差探测原理,本地振荡器输出信号与探测信号混频得到一路信号,经90°移相后的本地振荡器输出信号再与探测信号混频得到另一路信号,利用这两路信号得到了多普勒频移量和声源振动的频率。利用扬声器激发的水面模拟振源进行实验,表明该电路可有效测量的振动频率范围为300 Hz~10 kHz,证明可用于水下光声通信。
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The zirconia-titania-ORMOSIL waveguide thin films with considerable optical quality were prepared by the sol-gel process. The refractive index (n) and the extinction coefficient (k) were determined by a scanning ellipsometer. Wavelength tunable output of distributed feedback waveguide lasing was demonstrated in Rhodamine 6G doped ZrO2 TiO2-ORMOSIL thin films by varying the temperature, and about 5.5 nm wavelength tuning range was achieved around the emission wavelength of 599 nm. The thermal-optic coefficient (dn/dT) of the active ZrO2-TiO2-ORMOSIL films was deduced. (c) 2005 Elsevier B.V. All rights reserved.