933 resultados para Intermediation in development


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Small non coding RNAs emerged as important characters in several biology aspects. Among then, the most studied are microRNAs (miRNAs) and short interfering RNAs (siRNAs), that regulate their target gene post-transcriptionally in plants, animals and RNAi pathway intermediates, respectively. Both of classes have similar biogenesis being processed by Dicer enzymes and subsequent association with Argonaute enzymes. In plants, miRNAs and siRNAs have important functions in development, genome integrity and biotic and abiotic stress responses. The advances in high-throughtput sequencing and in silico analisys provide the uncover of new small non coding RNAs classes, many of them with unknown functions and biogenesis. tRNA derived small RNAs (tRFs) are a small non coding RNA class, that have as precursor a tRNA molecule. These were uncovers in the last decade in many organisms and, recently, in plants. Recent works detected tRFs from different sizes, with different source portions of the mature tRNA molecule (5’ end; 3’ end, anti-codon loop) and some from the tRNA precursor (pre-tRNA), suggesting that may be a novel class of small RNA and not random degradation products. Works in humans showed that some tRFs are processed by the Dicer enzymes, have association with the Argonaute enzymes and cell differentiation, tumor appearance and gene silencing related functions. Works in Arabidopsis and pumpkin (Cucurbita maxima) showed, respectively, that the tRFs have nutritional stress response possible functions and long distance signaling function between source and drain tissues, and may affect the translation. The tRFs biogenesis in plants are, until now an unknown, absence information about it in the literature and its possible biological functions are few studied yet, making then interesting target for studies among the small non coding RNAs in plants

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This work aims the design and analysis of a thrust frame system for a liquid fuel rocket engine. The project was developed following the design requirements established by the Division of Space Propulsion of the Institute of Aeronautics and Space. The layout of the structure was developed with the aid of a software of 3D modeling and static and dynamic analysis were performed by using a finite element package. The results of the analyzes helped in defining the layout of the structure which met all design requirements. The safety factor and the mass achieved were comfortably low, which may be useful in the future because the liquid fuel rocket engine is still in development

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Matemática Universitária - IGCE

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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This paper aims to trigger a reflection on inclusive education in early childhood education, considering education as an inclusive educational model endorsed by public policies, but still far from school reality. The reflection aims to think about necessary changes since early childhood education,because this is the first stage of basic education and it is a critical period in development and learning process of children with disabilities. The construction of the inclusive school since early childhood education involves thinking about its space, time, professional, educational resources etc..,turning to the possible access, retention and development to students with disabilities, students that, because of their particular characteristics, have a special educational necessity. The text discusses, among other things, the necessity to rethink pedagogical practice as a key of school inclusion in early childhood education. The inclusive pedagogical practice should be constituted by the junction of the acquired knowledge by the teacher throughout his career and by the availability to seek new ways to do it considering students diversity and their individual characteristics.

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This paper presents methodological considerations related to the study of the plant lexicon of the Juruna ethnic group, an indigenous people of the Xingu Indigenous Park, Mato Grosso State, Brazil. The language of this ethnic group, along with that spoken by the Xipaya, belongs to the Juruna family of the Tupi stock. It is a tonal language with SOV syntactic structure (Fargetti 1992, 2007), and presents interesting processes of reduplication (Fargetti 1997). Part of our broader research project on the lexicology and lexicography of the language, research on the Juruna plant lexicon is still in development, together with studies of other semantic fields such as birds, material culture, and kinship relations. However, it is already possible to see interesting linguistic issues involving word formation, as well as issues of the relationship between language and culture (especially those related to “perspectivism”). These issues are presented in this paper.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Agronomia (Produção Vegetal) - FCAV

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Pós-graduação em Ciência da Informação - FFC

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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In this paper we present two studies, the first one completed and the second one in development, which are based in teaching approaches that propose the qualitative study of mathematical models as a strategy for the teaching and learning of mathematical concepts. These teaching approaches focus on subjects from Higher Education such as Introduction to Ordinary Differential Equations and Topics of Differential and Integral Calculus. We denominate this common aspect of the teaching approaches as Model Analysis and in a preliminary level we relate it with Mathematical Modeling. Furthermore, we discuss some questions related with the choice of the theme and the role of Digital Technologies when Model Analysis is applied.