Exterior view of the Boehm family hat factory; Novy Jicin, Czech Republic Businesses

Tovarna na Klobouky Fv. Boehm

Reproduction of photograph of Kaufman and Rosenberg family portrait on the occasion of the wedding of Ludwig Rosenberg and Paula Rosenberg nee Joseph (left); Hamburg.

Includes Ludwig Rosenberg and Paula Rosenberg nee Joseph (left), Thekla (Tekie) Joseph (standing center), Karl Kaufman and Else Kaufman (right)

G-protein beta3 subunit gene (GNB3) variant in causation of essential hypertension

-Essential hypertensives display enhanced signal transduction through pertussis toxin-sensitive G proteins. The T allele of a C825T variant in exon 10 of the G protein beta3 subunit gene (GNB3) induces formation of a splice variant (Gbeta3-s) with enhanced activity. The T allele of GNB3 was shown recently to be associated with hypertension in unselected German patients (frequency=0.31 versus 0.25 in control). To confirm and extend this finding in a different setting, we performed an association study in Australian white hypertensives. This involved an extensively examined cohort of 110 hypertensives, each of whom were the offspring of 2 hypertensive parents, and 189 normotensives whose parents were both normotensive beyond age 50 years. Genotyping was performed by polymerase chain reaction and digestion with BseDI, which either cut (C allele) or did not cut (T allele) the 268-bp polymerase chain reaction product. T allele frequency in the hypertensive group was 0.43 compared with 0.25 in the normotensive group (chi2=22; P=0.00002; odds ratio=2.3; 95% CI=1.7 to 3.3). The T allele tracked with higher pretreatment blood pressure: diastolic=105+/-7, 109+/-16, and 128+/-28 mm Hg (mean+/-SD) for CC, CT, and TT, respectively (P=0.001 by 1-way ANOVA). Blood pressures were higher in female hypertensives with a T allele (P=0.006 for systolic and 0.0003 for diastolic by ANOVA) than they were in male hypertensives. In conclusion, the present study of a group with strong family history supports a role for a genetically determined, physiologically active splice variant of the G protein beta3 subunit gene in the causation of essential hypertension.

Herz? family studio portrait.

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Family portrait of siblings Wladimir, Rosa, Lena and Georg Eliasberg; New York Portraits Family

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Rieser family portrait on the steps of an unidentified building Portraits Family

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Portrait of a family and their dog sitting in a park Portraits Family

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Portrait of brother, mother and sister of Max Rieser seated outdoors; Franzensbad Portraits Family

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Theoretical study of a 16-µm CO2 downstream-mixing gasdynamic laser: A two-dimensional approach

A 16-µm CO2-N2 downstream-mixing gasdynamic laser, where a cold CO2 stream is mixed with a vibrationally excited N2 stream at the exit of the nozzle, is studied theoretically. The flow field is analyzed using a two-dimensional, unsteady, laminar and viscous flow model including appropriate finite-rate vibrational kinetic equations. The analysis showed that local small-signal gain up to 21.75 m−1 can be obtained for a N2 reservoir temperature of 2000 K and a velocity ratio of 1:1 between the CO2 and N2 mixing streams. Applied Physics Letters is copyrighted by The American Institute of Physics.

Saalfeld Family Collection

Xerox copy of chapter on Saalfeld family (includes family tree); photos of family paintings of Jettchen Gebert.

Feibelmann Family Collection 1796-1958

Family history and genealogy of Feibelmann family.

Levor Family 1763-1974

Photocopy of family tree of Levor and related families.

Mauerberger Family 1823-1957

Photocopy of family tree of Mauerberger and related families.

Philipp-Coppel Family 1781-1908

Photocopy of family history (Chronik) of Philipp and Coppel family.