Clinical Characterization of Asymptomatic or Minimally Symptomatic Young Patients Showing Signs Compatible With Dry Eye: A Pilot Study

Purpose: To evaluate and characterize the clinical profile of young asymptomatic or minimally symptomatic patients without diagnosis of dry eye but showing signs compatible with dry eye syndrome (DES). Methods: Prospective study including a total of 50 consecutive subjects with ages ranging from 18 to 40 years that were identified as asymptomatic or minimally symptomatic by means of the Ocular Surface Disease Index (OSDI) (score of <22). In all patients, a complete battery of tests for the diagnosis of DES was performed including the evaluation of the tear film break-up time (TFBUT), the level of corneal and conjunctival staining, and the eyelid and Meibomian morphology. Results: The OSDI score was significantly higher in women than in men (median: 12.5 vs. 5.3, P=0.01). Low grades of ocular surface staining, dysfunction of Meibomian gland expression, and alteration of quality of Meibomian secretions were observed in 56%, 58%, and 84% of eyes, respectively. More eyes with some dysfunction of Meibomian gland expressibility had a TFBUT less than 5 sec (P=0.033). A statistically significant difference in the OSDI score was found between patients with and without systemic allergies (P=0.036) and between male and female (P=0.01). Likewise, the OSDI score was significantly higher in those women wearing contact lenses compared with those not wearing them (P=0.012). Conclusions: Asymptomatic or minimally symptomatic young subjects may present low grades of clinical signs compatible with DES, with a trend to more symptomatology in women and allergic patients. These outcomes should be confirmed in future studies with larger samples.

Rabbinical manuscripts of Judah Monis, ca. 1700s

This leather-bound volume contains ten handwritten Hebrew texts presumably compiled by Judah Monis in the early 18th century. The pieces range from three to 150 pages on different sized leaves and appear to be in multiple hands. The last page of the volume has the struck-through inscription, "Judah Monis' Book" and accompanies a 44-page text. The texts are unattributed and undated, but have been identified as transcriptions of cabalistic writings and include a short biography of Isaac Luria (1533-1572) and extracts from the work of Luria, Hayyim ben Joseph Vital, Jacob ben Hayyim Zemah, Abraham ben Isaac of Granada, and Naphtali Bachrach. The transcriptions appear to be unattributed and undated.

Silua de varia lection / compuesta por el Magnifico cauallero Pero Mexia.

Lugar e impresor tomados del colofón

Escritores del siglo XVI ...

t. 1. San Juan de la Cruz. Fray Pedro Malon de Chaide. Fray Hernando de Zárate.--t. 2. Obras del maestro fray Luis de Leon. Precédelas su vida, escrita por Don Gregoria Mayans y Siscar, y un extracto del proceso instruido contra el autor desde el año 1571 al 1576.

Der grössere Catechismus /

Mode of access: Internet.

The Florida of the Inca; a history of adelantado, Hernando de Soto, Governor and Captain General of the kingdom of Florida, and of other heroic Spanish and Indian cavaliers,

Translation of La Florida del Inca.

Spanish explorers in the southern United States, 1528-1543 : The narrative of Alvar Nuñez Cabeça de Vaca,

Mode of access: Internet.

Maria Stuart; ein trauerspiel,

"The text is that of the standard Cotta edition."--Pref.

Deutsche Reichstagsakten : jüngere Reihe /

Vol. 8 lacks edition statement.

Sh. u-t. ʼOhole tam : ṿe-hu ḥeleḳ 1 mi-sefer Tumat Yesharim/

Cover title: Tumat yesharim.

Maria Stuart /

Mode of access: Internet.

Maria Stuart ; ein trauerspiel, von Friedrich Schiller.

"The text is that of the standard Cotta edition."--Pref.