Aging of intrauterine tissues in spontaneous preterm birth and preterm premature rupture of the membranes: a systematic review of the literature

Many adverse pregnancy outcomes (APOs), including spontaneous preterm birth (PTB), are associated with placental dysfunction. Recent clinical and experimental evidences suggest that premature aging of the placenta may be involved in these events. Although placental aging is a well-known concept, the mechanisms of aging during normal pregnancy and premature aging in APOs are still unclear. This review was conducted to assess the knowledge on placental aging related biochemical changes leading to placental dysfunction in PTB and/or preterm premature rupture of membranes (pPROM). We performed a systematic review of studies published over the last 50 years in two electronic databases (Pubmed and Embase) on placental aging and PTB or pPROM. The search yielded 554 citations, 30 relevant studies were selected for full-text review and three were included in the review. Only one study reported oxidative stress-related aging and degenerative changes in human placental membranes and telomere length reduction in fetal cells as part of PTB and/or pPROM mechanisms. Similarly, two animal studies reported findings of decidual senescence and referred to PTB mechanisms. Placental and fetal membrane oxidative damage and telomere reduction are linked to premature aging in PTB and pPROM but the risk factors and biomolecular pathways causing this phenomenon are not established in the literature. However, no biomarkers or clinical indicators of premature aging as a pathology of PTB and pPROM have been reported. We document major knowledge gaps and propose several areas for future research to improve our understanding of premature aging linked to placental dysfunction.

Aging voice and the laryngeal muscle atrophy

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Polymerization kinetics and polymerization stress in resin composites after accelerated aging as a function of the expiration date

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Chromatic stability of acrylic resins of artificial eyes submitted to the accelerated aging and polishing

Esthetics and durability of materials used to fabricate artificial eyes has been an important issue since artificial eyes are essential to restore esthetics and function, protect the remaining tissues and help with patients' psychological therapy. However, these materials are submitted to degrading effects of environmental agents on the physical properties of the acrylic resin. OBJECTIVE: This study assessed the color stability of acrylic resins used to fabricate sclera in three basic shades (N1, N2 and N3) when subjected to accelerated aging, mechanical and chemical polishing. MATERIAL AND METHODS: Specimens of each resin were fabricated and submitted to mechanical and chemical polishing. Chromatic analysis was performed before and after accelerated aging through ultraviolet reflection spectrophotometry. RESULTS: All specimens revealed color alteration following polishing and accelerated aging. The resins presented statistically significant chromatic alteration (p<0.01) between the periods of 252 and 1008 h. CONCLUSIONS: Both polishing methods presented no significant difference between the values of color derivatives of resins.

O papel da Universidade Aberta à Terceira Idade na educação ambiental

Population aging and environmental protection have gained special importance after the economic, demographic and social recent changes. The objective of this paper was to promote theoretical and reflective review with emphasis on convergence between sustainable development and educational activities promoted by the University of the Third Age. We conducted a literature review to give full articles from the descriptors: aged, sustainable development indicators and environmental protection, published in English, Spanish and Portuguese, between January 1994 and June 2014, in national and international journals on the basis LiIlacs, Bireme and Medline. We used systematic data collection for sample analysis. The results indicate that the University of the Third Age develops teaching, research and extension, through actions based on aging and educational assumptions. In this context, environmental education is presented as a pedagogical process capable of awakening the critical capacity of the elderly, making it active social worker and leading him to a cultural design which ensures establishment of sustainable harmonious relationship with nature. It was concluded that the University of the Third Age contributes to initiatives that emphasize the relationships between systems and economic processes or social and natural processes, generating the construction of social values, knowledge, skills, attitudes and skills aimed at the conservation of the environment.

Development of an anti aging cream with AHA/BHA and sunscreens

The skin aging is a matter of discomfort verified in the population. Thus, every day, new products are launched on the market to offer different manners to prevent the premature aging of the skin. In this context, active substances, as alpha and beta hidroxyacids (AHA/BHA), beyond the sunscreens, are considered a way of prevention and amelioration of the effects caused in the skin due to the time. The aim of this study was to develop and evaluate a cosmetic cream containing AHA/BHA and sunscreen. It was studied in relation to its physical-chemical and microbiological characteristics. According to the results, the formulation developed present a shelf life of 758 days and the preservative system was effective. Considering the parameters evaluated, the cream probably would be commercially accepted.

Development of an anti-aging cream with AHA/BHA and sunscreens

The skin aging is a matter of discomfort verified in the population. Thus, every day, new products are launched on the market to offer different manners to prevent the premature aging of the skin. In this context, active substances, as alpha and beta hidroxyacids (AHA/BHA), beyond the sunscreens, are considered a way of prevention and amelioration of the effects caused in the skin due to the time. The aim of this study was to develop and evaluate a cosmetic cream containing AHA/BHA and sunscreen. It was studied in relation to its physical-chemical and microbiological characteristics. According to the results, the formulation developed present a shelf life of 758 days and the preservative system was effective. Considering the parameters evaluated, the cream probably would be commercially accepted.

Cobertura sobre Terceira Idade na imprensa brasileira

This article intends to inventory the medias that also cover Third Age in Brazil, in view of that all the demographic pointers reveal the accented process of aging of the worldwide population, and therefore of our country. A time that the journalists cannot ignore the changes that occur in the interior of the society, in which it is the main area of performance of the journalism, we want to understand why the Brazilian media still dedicates so little space to this phenomenon of the elderly, in contrast of what occurs in other countries. We ask ourselves, then, if the change in the way of looking at the elderly one would not have to be born inside of the University, through the young who prepare for the exercise of the profession, with citizenship and social concern. In the Course of Journalism of the UNESP/Bauru a group of future journalists is searching this subject, for this they sign this article.

Jornalismo e sociedade: a Invisibilidade do idoso na imprensa brasileira

This article intends to inventory the medias that also cover Third Age in Brazil, in view of that all the demographic pointers reveal the accented process of aging of the world-wide population, and therefore of our country. A time that the journalists cannot ignore the changes that occur in the interior of the society, in which it is the main area of performance of the journalism, we want to understand why the Brazilian media still dedicates so little space to this phenomenon of the elderly, in contrast of what occurs in other countries. We ask ourselves, then, if the change in the way of looking at the elderly one would not have to be born inside of the University, through the young who prepare for the exercise of the profession, with citizenship and social concern.

Jornalismo e sociedade: a (in) visibilidade do idoso na imprensa brasileira

This article intends to inventory the medias that also cover Third Age in Brazil, in view of that all the demographic pointers reveal the accented process of aging of the world-wide population, and therefore of our country. A time that the journalists cannot ignore the changes that occur in the interior of the society, in which it is the main area of performance of the journalism, we want to understand why the Brazilian media still dedicates so little space to this phenomenon of the elderly, in contrast of what occurs in other countries. We ask ourselves, then, if the change in the way of looking at the elderly one would not have to be born inside of the University, through the young who prepare for the exercise of the profession, with citizenship and social concern. In the Course of Journalism of the UNESP/Bauru a group of future journalists is searching this subject, for this they sign this article.

Jornalismo e sociedade: a (in) visibilidade do idoso na imprensa

This article intends to inventory the medias that also cover Third Age in Brazil, in view of that all the demographic pointers reveal the accented process of aging of the world-wide population, and therefore of our country. A time that the journalists cannot ignore the changes that occur in the interior of the society, in which it is the main area of performance of the journalism, we want to understand why the Brazilian media still dedicates so little space to this phenomenon of the elderly, in contrast of what occurs in other countries. We ask ourselves, then, if the change in the way of looking at the elderly one would not have to be born inside of the University, through the young who prepare for the exercise of the profession, with citizenship and social concern. In the Course of Journalism of the UNESP/Bauru a group of future journalists is searching this subject, for this they sign this article.

Correlação entre a força muscular do assoalho pélvico e status hormonal da vagina em mulheres continentes

Pós-graduação em Bases Gerais da Cirurgia - FMB

Fatores dietéticos, antropométricos e socioeconômicos associados à sarcopenia em idosos: estudo transversal de base populacional

Pós-graduação em Saúde Coletiva - FMB

A New Birth-Interval Approach to Estimating Demographic Parameters of Humpback Whales

A demographic model is developed based on interbirth intervals and is applied to estimate the population growth rate of humpback whales (Megaptera novaeangliae) in the Gulf of Maine. Fecundity rates in this model are based on the probabilities of giving birth at time t after a previous birth and on the probabilities of giving birth first at age x. Maximum likelihood methods are used to estimate these probabilities using sighting data collected for individually identified whales. Female survival rates are estimated from these same sighting data using a modified Jolly–Seber method. The youngest age at first parturition is 5 yr, the estimated mean birth interval is 2.38 yr (SE = 0.10 yr), the estimated noncalf survival rate is 0.960 (SE = 0.008), and the estimated calf survival rate is 0.875 (SE = 0.047). The population growth rate (l) is estimated to be 1.065; its standard error is estimated as 0.012 using a Monte Carlo approach, which simulated sampling from a hypothetical population of whales. The simulation is also used to investigate the bias in estimating birth intervals by previous methods. The approach developed here is applicable to studies of other populations for which individual interbirth intervals can be measured.

Fatores dietéticos, antropométricos e socioeconômicos associados à sarcopenia em idosos: estudo transversal de base populacional

Pós-graduação em Saúde Coletiva - FMB