918 resultados para Boost
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Introduction. Shale gas is an unconventional form of gas1 because its extraction is more difficult or less economical than that of conventional natural gas. It has become an important item of energy policy during the last years since new processes have allowed its extraction. In the medium term, shale gas should foster a reinforcement of the gas part in the world’s energy mix. In 2011, the IEA released an influential report entitled “Are we entering a golden age of gas?” This report suggests that shale gas could help substantially boost global gas use.2 It also warns at the same time that this success could bring into question the international goal of limiting the long-term increase in the global temperature to 2° C above pre-industrial levels. In the world economy, the impact of shale gas is increasing rapidly (especially in the USA, albeit apparently not as significantly as expected3). In the EU, its perspectives remain uncertain, for many reasons. Estimates are not reliable. Shale gas exploitation remains a controversial issue due to geology, lack of infrastructure and also fears for the environment and public health. The EU institutions seem to have a favorable attitude towards shale gas development while the Member States’ attitude seems to vary from enthusiasm to hesitation or opposition. Public opinion on the issue appears quite divided everywhere. This brief paper will examine various estimations of potential resources in the EU (§ 1), the potential costs and benefits (§ 2), the initiatives taken by the EU institutions (§ 3) and the national authorities (§ 4), and finally the emerging EU framework (§ 5). The conclusion is, rather surprisingly, that whatever happens on this front, this will not modify the present structural challenges of the EU in the domains of climate and energy.4
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FOREWORD. When one looks at the present state of the CSDP, one cannot help but look on with disenchantment at the energy that appears to have abandoned both institutions and Member States. Commentators increasingly take for granted that nothing much should be expected from this field of EU policy. The reasons for this state of mind are well known: the recent economic and financial strains, which have impacted all EU action since 2008, means that most of the Member States will struggle to keep their defence budgets at their present level in the future, and we may even see reductions. Furthermore, and to put it mildly, most of the recent CSDP operations have also experienced a lack of enthusiasm. Adding to this overall trend, the EU is far from presenting a common vision of what security and defence should really mean. Many of the Member States do not want to be involved in all of today’s international turmoils, and they rarely share the strategic culture which inspires those Member States who see themselves as having special responsibilities in dealing with these crises. In the end it may be that Member States diverge fundamentally on the simple question of whether it is relevant for the EU to engage in most of the ‘hot’ crises Europe faces; many prefer to see Europe as a soft power, mostly dedicated to intervening on less dramatic fronts and more inclined to mend than to fight. For whatever reason given, it remains that if there is a lack of common understanding on what CSDP should really be about, it should not come as a surprise if this policy is presently in stalemate. As an additional blow, the Ukrainian crisis, which dragged on for the whole of last year, could only add to the downward spiral the EU has been experiencing, with a new Russia aggressively confronting Europe in a manner not too distant from the Cold War days. This attitude has triggered the natural reaction among EU Member States to seek reassurances from NATO about their own national security. Coupled with the return of France a few years ago into the integrated military command, NATO’s renewed relevance has sent a strong message to Europe about the military organisation’s credibility with regard to collective defence. Surprisingly, this overall trend was gathering momentum at the same time as other more positive developments. The European Council of December 2013 dedicated its main session to CSDP: it underlined Europe’s role as a ‘security provider’ while adopting a very ambitious road map for Europe in all possible dimensions of the security sector. Hence the impression of a genuine boost to all EU institutions, which have been invited to join efforts and give CSDP a reinvigorated efficiency. In the same way, the increasing instability in Europe’s neighbourhood has also called for more EU operations: most recently in Iraq, Libya, Northern Nigeria or South Sudan. Pressure for further EU engagement has been one of the most constant features of the discussions taking place around these crises. Moreover, a growing number of EU partners in Asia, Latin America or Eastern Europe have shown a renewed eagerness to join CSDP missions in what sounds like a vote of confidence for EU capacities. What kind of conclusion should be drawn from this contradictory situation? Probably that the EU has much more potential than it can sometimes figure out itself, if only it would be ready to adapt to the new global realities. But, more than anything else, an enhanced CSDP needs from all Member States strong political will and a clear vision of what they want this policy to be. Without this indispensable ingredient CSDP may continue to run its course, as it does today. It may even grow in efficiency but it will keep lacking the one resource that would definitely help it overcome all the present shortcomings that have prevented Europe from finding its true role and mission through the CSDP. Member States remain central to EU security and defence policy. This is why this collection of essays is so valuable for assessing in no uncertain way the long road that lies ahead for any progress to be made. Pierre VIMONT Senior Associate at Carnegie Europe Former Executive Secretary-General of the European External Action Service
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One thing is clear: the Greek people have emphatically voted ‘No’, providing a boost to Prime Minister Alexis Tsipras and plunging Greece and the Eurozone even more into uncertainty. But it might, at the end of the day, prove to be a hollow victory for the Greek Prime Minister: the vote cannot compel the rest of the Eurozone to open their coffers and provide the funds Greece so desperately needs. It is certainly not a victory for democracy: it is highly questionable whether the Greek people could form an informed opinion, given the short time frame, the unclear question relying on a proposal no longer on the table, and the high level of misinformation on the potential consequences of the vote. This is no victory, neither for Greece nor the EU and its members: in the end, it increases the danger of Greece leaving the Eurozone – and potentially even an eventual exit from the EU –, which the people of Greece clearly do not want, as 75-80 per cent of citizens firmly want the country to stay in the euro.
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Against the background of the rapidly growing number of asylum-seekers, Daniel Gros argues in this CEPS Commentary that the EU needs to take action on two fronts. First, member countries must urgently boost their capacity to deal with asylum applications, so that they can quickly identify those who truly deserve protection. Second, the EU needs to improve burden-sharing in providing shelter for those who gain asylum. In his view, international law – and basic morality – demands nothing less.
China's ETS: A vote of confidence in carbon markets ahead of Paris. CEPS Commentary, 12 October 2015
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In this CEPS commentary, Andrei Marcu welcomes the recent announcement by President Xi Jinping that China will start a national emissions trading scheme in 2017. Calling it a "genuine game changer" in the global climate talks, Marcu describes the decision as giving a much-needed boost to carbon markets and cap-and-trade as the preferred way forward for those economies that have the capacity, the depth and the breadth for a liquid carbon market.
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When in 2012 China approached the countries of Central and Eastern Europe (CEE) with a proposal of cooperation in the ‘16+1’ formula, it declared it was willing to meet the needs of CEE countries. Beijing had been aware of the political importance of the problem of trade deficit (which has been ongoing for years) and launched cooperation with the governments of 16 CEE countries to boost imports from these states. The years 2011–2014 brought an improvement in the balance of trade between China and: Hungary, Latvia, the Czech Republic, Romania, Bulgaria and Croatia. The remaining ten CEE countries recorded an increase in their trade deficits. Changes in CEE countries’ balance of trade with China resulted only slightly from political actions. Instead, they were due to the macroeconomic situation and to a deterioration of the debt crisis in the EU which, for example, caused a decline in the import of Chinese goods in some of these countries. Multilateral trade cooperation was successfully developed in the entire region only in the agricultural and food production sector – the area of greatest interest to China. The pace of bilateral cooperation with specific countries varied, with the fastest being Poland, Latvia, Romania, Hungary and Bulgaria. Actions by governments of CEE countries resulted in Chinese market opening up to hundreds of local companies which, in turn, translated into an increase in the volume of foodstuffs sold by ‘the 16’ to China from US$ 137 million in 2011 to US$ 400 million in 2014. The success achieved in the agricultural and food production sector has demonstrated the effectiveness of trade cooperation in the ‘16+1’ formula. It is, however, insufficient to generate a significant improvement of the trade balance. At present, the sector’s share in the total volume of goods sold to China by CEE states is a mere 3.7%, and any reduction of the trade deficit would require long-term and more comprehensive solutions still to be implemented by the governments of individual CEE states.
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After Japan’s snap Lower House elections called on December 14 by old – and now new – Prime Minister Shinzo Abe, it will hopefully be the former, but probably the latter. This is the very opposite of what Abe promised would happen after his two-year tenure, which included many missed opportunities to adopt badly needed economic reforms capable of leading the country back onto a path of sustainable economic growth. While the jury is still out on whether Abe will focus this time around on economic reforms as opposed to attempts to boost the country’s defense profile and get rid of Japan’s constitutionally prescribed pacifism, his (very) nationalist and at times revisionist political track record suggests that it could be the latter yet again.
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Portugal provides a large number of factors that boost the development of the national equestrian tourism. It represents an opportunity for the qualification and differentiation of the national tourism, to stimulate rural economies, to combat seasonality and asymmetries.This study want to understand the importance, for the equestrian tourist, of the critical success factors such as the Lusitano horse, the national equestrian culture, the landscape diversity, among others. Also, how they can contribute to the differentiation of the national equestrian tourism for international destinations that are already deployed in the market.For this study is crucial to know the perspective of those involved in the various equestrian tourism activities. In this sense, a group of companies were selected and exploratory interviews were conducted that contributed to important outputs in the construction of the questionnaire.The research was attended by 110 individuals, with different profiles, motivations and types of involvement. From the analysis, it is concluded that the critical success factors are significant in motivating equestrian tourists, namely the quality of equestrian infrastructures, the Lusitano horse, the hospitality, among others. It is also possible to analyze that the equestrian tourist demonstrates a strong commitment: they are knowledgeable, read a lot about riding and belong to equestrian clubs.Finally, the factor analysis highlight the agreement between participants and a significant number of statements made in the questionnaire related to motivation and involvement. It is possible to conclude that equestrian tourists look for relaxing moments and opportunities to expand their equestrian knowledge.
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The adenylate cyclase toxoid (ACT) of Bordetella pertussis is capable of delivering its N-terminal catalytic domain into the cytosol of CD11b-expressing professional antigen-presenting cells such as myeloid dendritic cells. This allows delivery of CD8+ T-cell epitopes to the major histocompatibility complex (MHC) class I presentation pathway. Recombinant detoxified ACT containing an epitope of the Plasmodium berghei circumsporozoite protein (CSP), indeed, induced a specific CD8+ T-cell response in immunized mice after a single application, as detected by MHC multimer staining and gamma interferon (IFN-gamma) ELISPOT assay. This CSP-specific response could be significantly enhanced by prime-boost immunization with recombinant ACT in combination with anti-CTLA-4 during the boost immunization. This increased response was accompanied by complete protection in a number of mice after a challenge with P. berghei sporozoites. Transient blockade of CTLA-4 may overcome negative regulation and hence provide a strategy to enhance the efficacy of a vaccine by amplifying the number of responding T cells.
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Includes bibliographical references.
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Esta tese apresenta uma configuração em que, numa rede social regida pelo princípio da ligação preferencial, nós periféricos buscam inflacionar artificialmente seus índices de centralidade, medida pelo grau de entrada, por meio do privilégio temporário da reciprocidade de ligações com outros nós periféricos. Para construir este cenário, criou-se uma rede com as características de uma rede acadêmica de citações entre artigos, em que os nós são artigos publicados por um conjunto de periódicos, e as ligações entre eles são as citações que cada artigo faz a outros artigos existentes. Esta rede foi condensada em outra, na qual os nós são os periódicos aos quais cada artigo da primeira rede está associado, e as ligações são o total de citações que os artigos de um periódico faz aos artigos de cada outro periódico. Implementou-se um método de simulação computacional, no qual, durante alguns ciclos, foram manipulados parâmetros relacionados à quantidade total de ligações (citações) entre periódicos periféricos, de forma a induzir os efeitos desejados de reciprocidade periférica, alterando a lógica de direcionamento de citações pela atribuição de maior probabilidade para que artigos de outros periódicos periféricos recebessem ligações, afastando-se da lógica da ligação preferencial, porém sem alterar qualquer outra característica intrínseca que representasse a capacidade de um artigo ou periódico atrair novas ligações. Chamou-se esta alteração da lógica de alocação de ligações entre periódicos periféricos de Comportamento Estratégico. Observou-se que o Comportamento Estratégico é capaz de trazer benefícios de centralidade medida por grau para aqueles periódicos em que ele foi induzido, e prejuízos para os demais periódicos periféricos, porém não é suficiente para que eles saiam do quartil periférico de centralidade a que pertenciam antes da manipulação dos efeitos. Além disso, observou-se que, na ausência de elementos que alterem a capacidade intrínseca de atração de ligações de um periódico, a interrupção do Comportamento Estratégico levou aos níveis anteriores de centralidade. Também se observou que o Comportamento Estratégico acarretou em alterações de centralidade medida por autovetor estatisticamente significativas, porém não esperadas, mas que, após sua interrupção, esta retornou aos patamares anteriores à indução dos efeitos.
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New residential scale photovoltaic (PV) arrays are commonly connected to the grid by a single dc-ac inverter connected to a series string of pv panels, or many small dc-ac inverters which connect one or two panels directly to the ac grid. This paper proposes an alternative topology of nonisolated per-panel dc-dc converters connected in series to create a high voltage string connected to a simplified dc-ac inverter. This offers the advantages of a converter-per-panel approach without the cost or efficiency penalties of individual dc-ac grid connected inverters. Buck, boost, buck-boost, and Cuk converters are considered as possible dc-dc converters that can be cascaded. Matlab simulations are used to compare the efficiency of each topology as well as evaluating the benefits of increasing cost and complexity. The buck and then boost converters are shown to be the most efficient topologies for a given cost, with the buck best suited for long strings and the boost for short strings. While flexible in voltage ranges, buck-boost, and Cuk converters are always at an efficiency or alternatively cost disadvantage.
Theory-of-mind development in oral deaf children with cochlear implants or conventional hearing aids
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Background: In the context of the established finding that theory-of-mind (ToM) growth is seriously delayed in late-signing deaf children, and some evidence of equivalent delays in those learning speech with conventional hearing aids, this study's novel contribution was to explore ToM development in deaf children with cochlear implants. Implants can substantially boost auditory acuity and rates of language growth. Despite the implant, there are often problems socialising with hearing peers and some language difficulties, lending special theoretical interest to the present comparative design. Methods: A total of 52 children aged 4 to 12 years took a battery of false belief tests of ToM. There were 26 oral deaf children, half with implants and half with hearing aids, evenly divided between oral-only versus sign-plus-oral schools. Comparison groups of age-matched high-functioning children with autism and younger hearing children were also included. Results: No significant ToM differences emerged between deaf children with implants and those with hearing aids, nor between those in oral-only versus sign-plus-oral schools. Nor did the deaf children perform any better on the ToM tasks than their age peers with autism. Hearing preschoolers scored significantly higher than all other groups. For the deaf and the autistic children, as well as the preschoolers, rate of language development and verbal maturity significantly predicted variability in ToM, over and above chronological age. Conclusions: The finding that deaf children with cochlear implants are as delayed in ToM development as children with autism and their deaf peers with hearing aids or late sign language highlights the likely significance of peer interaction and early fluent communication with peers and family, whether in sign or in speech, in order to optimally facilitate the growth of social cognition and language.
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Conotoxins (CTXs), with their exquisite specificity and potency, have recently created much excitement as drug leads. However, like most peptides, their beneficial activities may potentially be undermined by susceptibility to proteolysis in vivo. By cyclizing the alpha-CTX MII by using a range of linkers, we have engineered peptides that preserve their full activity but have greatly improved resistance to proteolytic degradation. The cyclic MII analogue containing a seven-residue linker joining the N and C termini was as active and selective as the native peptide for native and recombinant neuronal nicotinic acetylcholine receptor subtypes present in bovine chromaffin cells and expressed in Xerl oocytes, respectively. Furthermore, its resistance to proteolysis against a specific protease and in human plasma was significantly improved. More generally, to our knowledge, this report is the first on the cyclization of disulfide-rich toxins. Cyclization strategies represent an approach for stabilizing bioactive peptides while keeping their full potencies and should boost applications of peptide-based drugs in human medicine.
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We show how to communicate Heisenberg-limited continuous (quantum) variables between Alice and Bob in the case where they occupy two inertial reference frames that differ by an unknown Lorentz boost. There are two effects that need to be overcome: the Doppler shift and the absence of synchronized clocks. Furthermore, we show how Alice and Bob can share Doppler-invariant entanglement, and we demonstrate that the protocol is robust under photon loss.