946 resultados para Biochemical engineering
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Resumo:
El presente documento analiza las características de liderazgo de los gerentes “baby boomers” de la empresa transnacional Global Engineering S.A., que tiene oficinas en España, Cuba, Venezuela y Ecuador. Esta investigación se realiza sobre la premisa que los Gerentes de las cuatro oficinas pertenecen a la generación de los baby boomers, por lo se presenta la hipótesis de que, al pertenecer a una misma generación las características de liderazgo son similares. Los objetivos de la presente investigación, fueron el identificar las características de liderazgo de los gerentes, analizarlas, verificar si son eficaces, identificar las oportunidades de mejora y presentar un plan de mejora para la organización. Al presente estudio se lo define como exploratorio, descriptivo y correlacional, se utiliza como herramienta principal para la investigación el MLQ 5X versión corta creado por Bass y Avolio y adaptado por Vega y Zabala, se lo aplica a las cuatro oficinas de la empresa tanto a los gerentes como a los seguidores. Para la comprobación de la hipótesis, se utilizó la prueba t de Student, para establecer valores máximos y mínimos de los promedios de las características de liderazgo, para de esa manera conocer si los Gerentes de cada oficina tienen las mismas características, también se promediaron los valores resultantes de cada estilo de liderazgo para conocer si son eficaces para la realidad de la organización. Como herramienta para la mejora de toma de decisiones estratégica, se presenta el Cuadro de Mando integral, se establecen los objetivos principales para las perspectivas y se señalan los pasos de cómo debe ser el proceso de implementación del plan de coaching gerencial para la organización. De la investigación realizada se concluye que las características de liderazgo de los gerentes de la organización no se relacionan directamente con la generación a la que pertenecen, sino, dependen más del entorno, la situación y de los seguidores. Se recomienda la implementación del Cuadro de Mando Integral para mejorar la toma de decisiones estratégicas, haciendo énfasis en la propuesta de valor de implementar un plan de coaching gerencial para los gerentes de las distintas oficinas para así mejorar la eficacia de la organización.
Resumo:
In all biological processes, protein molecules and other small molecules interact to function and form transient macromolecular complexes. This interaction of two or more molecules can be described by a docking event. Docking is an important phase for structure-based drug design strategies, as it can be used as a method to simulate protein-ligand interactions. Various docking programs exist that allow automated docking, but most of them have limited visualization and user interaction. It would be advantageous if scientists could visualize the molecules participating in the docking process, manipulate their structures and manually dock them before submitting the new conformations to an automated docking process in an immersive environment, which can help stimulate the design/docking process. This also could greatly reduce docking time and resources. To achieve this, we propose a new virtual modelling/docking program, whereby the advantages of virtual modelling programs and the efficiency of the algorithms in existing docking programs will be merged.
Resumo:
Perchlorate-reducing bacteria fractionate chlorine stable isotopes giving a powerful approach to monitor the extent of microbial consumption of perchlorate in contaminated sites undergoing remediation or natural perchlorate containing sites. This study reports the full experimental data and methodology used to re-evaluate the chlorine isotope fractionation of perchlorate reduction in duplicate culture experiments of Azospira suillum strain PS at 37 degrees C (Delta Cl-37(Cr)--ClO4-) previously reported, without a supporting data set by Coleman et al. [Coleman, M.L., Ader, M., Chaudhuri, S., Coates,J.D., 2003. Microbial Isotopic Fractionation of Perchlorate Chlorine. Appl. Environ. Microbiol. 69, 4997-5000] in a reconnaissance study, with the goal of increasing the accuracy and precision of the isotopic fractionation determination. The method fully described here for the first time, allows the determination of a higher precision Delta Cl-37(Cl)--ClO4- value, either from accumulated chloride content and isotopic composition or from the residual perchlorate content and isotopic composition. The result sets agree perfectly, within error, giving average Delta Cl-37(Cl)--ClO4- = -14.94 +/- 0.15%omicron. Complementary use of chloride and perchlorate data allowed the identification and rejection of poor quality data by applying mass and isotopic balance checks. This precise Delta Cl-37(Cl)--ClO4-, value can serve as a reference point for comparison with future in situ or microcosm studies but we also note its similarity to the theoretical equilibrium isotopic fractionation between a hypothetical chlorine species of redox state +6 and perchlorate at 37 degrees C and suggest that the first electron transfer during perchlorate reduction may occur at isotopic equilibrium between art enzyme-bound chlorine and perchlorate. (C) 2008 Elsevier B.V. All rights reserved.
Resumo:
The aim of this study was to examine interrelationships between functional biochemical and microbial indicators of soil quality, and their suitability to differentiate areas under contrasting agricultural management regimes. The study included five 0.8 ha areas on a sandy-loam soil which had received contrasting fertility and cropping regimes over a 5 year period. These were organically managed vegetable, vegetable -cereal and arable rotations, an organically managed grass clover ley, and a conventional cereal rotation. The organic areas had been converted from conventional cereal production 5 years prior to the start of the study. All of the biochemical analyses, including light fraction organic matter (LFOM) C and N, labile organic N (LON), dissolved organic N and water-soluble carbohydrates showed significant differences between the areas, although the nature of the relationships between the areas varied between the different parameters, and were not related to differences in total soil organic matter content. The clearest differences were seen in LFOM C and N and LON, which were higher in the organic arable area relative to the other areas. In the case of the biological parameters, there were differences between the areas for biomass-N, ATP, chitin content, and the ratios of ATP: biomass and basal respiration: biomass. For these parameters, the precise relationships between the areas varied. However, relative to the conventionally managed area, areas under organic management generally had lower biomass-N and higher ATP contents. Arbuscular mycorrhizal fungus colonization potential was extremely low in the conventional area relative to the organic areas. Further, metabolic diversity and microbial community level physiological profiles, determined by analysis of microbial community metabolism using Biolog GN plates and the activities of eight key nutrient cycling enzymes, grouped the organic areas together, but separated them from the conventional area. We conclude that microbial parameters are more effective and consistent indicators of management induced changes to soil quality than biochemical parameters, and that a variety of biochemical and microbial analyses should be used when considering the impact of management on soil quality. (C) 2004 Elsevier Ltd. All rights reserved.