925 resultados para Auto-stimulation intracérébrale


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To validate a model for investigating the effects of analgesic drugs on mechanical, thermal and electrical stimulation testing. To investigate repeatability, sensitivity and specificity of nociceptive tests. Randomised experiment with 2 observers in 2 phases. Mechanical (M), thermal (TL) and electrical (E) stimuli were applied to the dorsal metacarpus (M-left and TL-right) and coronary band of the left thoracic limb (E) and a thoracic thermal stimulus (TT) was applied caudal to the withers in 8 horses (405 ± 43 kg). Stimuli intensities were increased until a clear avoidance response was detected without exceeding 20 N (M), 60°C (TL and TT) and 15 V (E). For each set of tests, 3 real stimuli and one sham stimulus were applied (32 per animal) using a blinded, randomised, crossover design repeated after 6 months. A distribution frequency and, for each stimulus, Chi-square and McNemar tests compared both the proportion of positive responses detected by 2 observers and the 2 study phases. The κ coefficients estimated interobserver agreement in determining endpoints. Sensitivity (384 tests) and specificity (128 tests) were evaluated for each nociceptive stimulus to assess the evaluators' accuracy in detecting real and sham stimuli. Nociceptive thresholds were 3.1 ± 2 N (M), 8.1 ± 3.8 V (E), 51.4 ± 5.5°C (TL) and 55.2 ± 5.3°C (TT). The level of agreement after all tests, M, E, TL and TT, was 90, 100, 84, 98 and 75%, respectively. Sensitivity was 89, 100, 89, 98 and 70% and specificity 92, 97, 88, 91 and 94%, respectively. The high interobserver agreement, sensitivity and specificity suggest that M, E and TL tests are valid for pain studies in horses and are suitable tools for investigating antinociceptive effects of analgesics in horses.

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Pós-graduação em Engenharia Civil - FEIS

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This work deals with the stages of the process of renewal of a Notice of Inspection of Fire Department (AVCB) set of structural measures, technical and organizational integrated to ensure the building an optimum level of protection in the security segment fire and panic according to the laws of fire safety standards. The work presented all the literature about the process, their justifications to force deploy in a company to fire safety, the benefits that this standard offers, the facilities in a company that has a AVCB and the great importance in society, presents some examples where there contained the fire safety regulations and their unhappy outcomes, difficulties encountered, examples of how to proceed, step by step and the lesson that this process requires great care, dedication, professionals with the required knowledge and severity to completion

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The objective of this study is to analyze the adoption of lean thinking practices at Brazilian auto part companies. For such, a survey was conducted at 75 sector companies. The results reveal that among all practices, the “systematic search for continuous improvement" obtained the highest implementation average. In terms of correlation, interdependence was observed among all Lean Manufacturing variables, most especially between LM5 (Kanban) and LM6 (Just-in-Time). This correlation can be explained by the importance of Kanban systems when implementing Just-inTime.

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Low adherence to physical exercise programs is a factor that contributes to the high rates of physical inactivity worldwide. In this sense, strategies to improve the affective responses during exercise are used to impact adherence, as the use of music and self-selected exercise intensity. Despite the benefits of these strategies, there are few studies involving the combination of both (self-selected intensity and music), especially in the elderly population. Thus, the aim of this study was to investigate the influence of music on performance, ratings of perceived exertion (RPE) and on affective and motivational responses of elderly during walking exercise with self-selected intensity. Eleven elderly performed walking sessions on an athletic track in three conditions: without music, with motivational music and with oudeterous music. RPE, mood states, motivation, affective responses, session RPE and attitudes related to the experience of exercise were evaluated. Results demonstrated that both motivational and oudeterous music improved affective responses and decreased RPE. However, only the motivational music condition showed an effect on distance walked, the only presenting a consistent increase in distance. Therefore, it is concluded that the use of music, particularly motivational music, besides increasing the distance walked, reduces RPE and increase pleasure of the elderly during the exercise. Such strategy, in addition to potentially impact adherence positively, can lead to greater benefits and physical adaptations related to the training in the long term

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The writings of this paper refer to several personal experiences as well as the various conflicts in the initial educational formation, where I'm reflecting about the formation intentions of this course. I do an analysis and a reflection of the pedagogical practices developed during graduation in institutional spaces, as well as the understanding of the complex context and teaching actions intrinsic to this, that are what constitute the structural dimensions which is where the formative process happens. This study is a narrative of initial formation as autobiographical. Memories and experiences are analyzed along with undergraduate education, exposing structural problems of course requiring a deeper analysis. In addition to analyse critically the institutional spaces of the (few) outreach programs, education and research that are the basis of the Brazilian University, the wellknown University quadripod. Under this perspective, the narrative brings the dichotomous design of the quadripod inside the University course, exposing the need to reflect on this fact, as it culminates in the formation of future teachers in physics. Nevertheless, the work seeks to raise awareness for the need for enhancement of teaching career at the University to address the teaching crisis which today proliferates in the educational institutions in Brazil, therefore it is necessary to the teachers to become aware of your profession and the vision as such. Only from this perspective one can discuss a proper teacher training, aiming at the integration of all activities, valuing all with the same importance

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A procriação excessiva de cães e gatos no ambiente urbano é um problema de saúde pública e de bem estar animal. Para se desenvolver campanhas de controle populacional necessita-se de protocolos cirúrgicos seguros, rápidos e de baixo custo. A abraçadeira auto-estática de náilon aparentemente se encaixa neste perfil. Objetivou-se avaliar por laparoscopia e histologia, a reação tecidual após a ligadura dos pedículos ovarianos com abraçadeira auto-estática ou mononáilon agulhado na ovariosalpingohisterectomia em 18 cadelas. Após 60 dias do procedimento cirúrgico não foi observada pela laparoscopia nenhuma aderência ou alteração macroscópica e a histologia dos fragmentos dos pedículos ovarianos demonstrou que a resposta tecidual não diferiu entre os métodos, revelando que a abraçadeira auto-estática pode ser usada como método de ligadura dos pedículos ovarianos de cadelas submetidas à ovariosalpingohisterectomia.

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This article introduces the concepts of self-organization and autonomy as presented by the thought of Michel Debrun and Edgar Morin and their relationship to the development of a bioethical conscience by means of the school educational process. The proposal aims to contribute to the development of autonomy of students and thus be conducive to their self-organization as “responsible ethical subjects”.

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The 1988 constitution makes an life is a supreme good when increased health as the fundamental condition requiring that all ill patient has the right to be treated in a public hospital (CF, art. 196). In this sense, the goal of this work is to generate a weekly forecast of hospital care by means of an advanced prediction model. It is expected that the model of self-regressivas seasonal moving averages SARIMA generate reliable and adherent to issue forecasts analyzed, thus enabling better resource allocation and more efficient hospital management